颅底骨髓炎的诊断治疗进展

田俊

doi:10.13201/j.issn.2096-7993.2023.07.015

颅底骨髓炎的诊断治疗进展

田俊^1, ,

- 首都医科大学附属北京友谊医院耳鼻咽喉头颈外科(北京，100050)

详细信息

通讯作者: 田俊，E-mail：zguotian@126.com

中图分类号: R765.5

收稿日期: 2022-07-05

刊出日期: 2023-07-03

Current diagnosis and treatment of skull base osteomyelitis

TIAN Jun^1, ,

- Department Otorhinolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China

More Information

Corresponding author: TIAN Jun, E-mail: zguotian@126.com

Received Date: 05 July 2022

Publish Date: 03 July 2023

摘要

摘要: 颅底骨髓炎是罕见且难治的致死性疾病，其主要病因为耳源性和鼻源性感染，有时与恶性肿瘤不易区分。随着抗生素的应用，诊断方法和颅底外科手术技术的进步，死亡率较之前明显改善。然而，该病的成功诊治仍然充满挑战，其诊断易延误，治疗周期长、易反复，且缺乏相应指南。本文旨在系统地综述颅底骨髓炎的诊断治疗进展。
- 骨髓炎 /
- 颅底骨髓炎 /
- 恶性外耳道炎 /
- 坏死性外耳道炎
Abstract: Skull base osteomyelitis is a rare, refractory, and potentially fatal disease primarily caused by otogenic and sino rhinogenic infections. At times, it can mimic neoplasia complicating the diagnosis. With the use of antibiotics, advancements in diagnostic methods, and skull base surgical techniques, the mortality rate has significantly improved. However, the successful diagnosis and treatment of the disease is still challenging due to delayed diagnosis, lengthy treatment course, a tendency for relapse and lack of guidelines. Therefore, this article aims to review the progress in the diagnosis and treatment of skull base osteomyelitis.
- osteomyelitis /
- skull base osteomyelitis /
- malignant otitis externa /
- necrotizing otitis externa

HTML全文

表 1 骨髓炎Cierny-Mader分期系统

病变解剖范围	患者健康状态分级
①骨髓质	A正常
②骨表面	Bs患者健康系统性受损
③局部的(全层的)	Bl患者健康局部减弱
④广泛的(渗透性的，环周的)	Bls患者健康系统性和局部受损 C治疗本身比疾病更有害
注：临床分期=病变解剖范围+健康状态分级

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