原发性甲状旁腺功能亢进症致高钙危象及术后骨饥饿综合征1例

张梦棣; 曾奕斐; 王蕾; 孙贻安; 李静蔚

doi:10.13201/j.issn.2096-7993.2023.05.014

原发性甲状旁腺功能亢进症致高钙危象及术后骨饥饿综合征1例

- 1.
  山东中医药大学(济南，250000)
- 2.
  山东中医药大学附属医院乳腺甲状腺外科
基金项目:
山东省医药卫生科技发展计划面上项目(No：202016001022)

详细信息

通讯作者: 李静蔚，E-mail：71000395@sdutcm.edu.cn

中图分类号: R582.1

收稿日期: 2021-09-01

修回日期: 2023-02-01

刊出日期: 2023-05-03

Hypercalcium crisis and postoperative hungry bone syndrome caused by primary hyperparathyroidism: a case report

- 1.
  Shandong University of Traditional Chinese Medicine, Ji'nan, 250000, China
- 2.
  Department of Breast and Thyroid Surgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine

More Information

Corresponding author: LI Jingwei, E-mail: 71000395@sdutcm.edu.cn

Received Date: 01 September 2021

Revised Date: 01 February 2023

Publish Date: 03 May 2023

摘要

摘要: 回顾1例原发性甲状旁腺功能亢进症(primary hyperparathyroidism，PHPT)所致高钙血症危象患者的诊疗过程以及骨饥饿综合征的预防性治疗。患者，男，32岁，高钙血症，主要临床表现为食欲不振、恶心、多尿、烦渴、乏力及嗜睡等。甲状旁腺激素和血清钙升高，甲状腺功能正常；甲状腺彩超、颈部MRI显示右甲状腺后方占位，放射性核素检查显示右甲状旁腺区显像剂浓度异常；有病理性骨折病史。临床上诊断为PHPT继发高钙血症危象。
- 原发性甲状旁腺功能亢进症 /
- 骨饥饿综合征 /
- 高钙危象
Abstract: To review the diagnosis and treatment of a case of hypercalcium crisis caused by primary hyperparathyroidism(PHPT) and prophylactic treatment of hungry bone syndrome. In a 32-year-old male with hypercalcemia, the main manifestations were loss of appetite, nausea, polyuria, polydipsia, fatigue, lethargy, etc. parathyroid hormone, serum calcium increased, thyroid function was normal, thyroid color ultrasound and MRI showed space-occupying behind the right thyroid, radionuclide examination showed abnormal imaging agent concentration in the right parathyroid area, there was a history of pathological fracture. Clinically diagnosed as hypercalcemia crisis secondary to PHPT.
- primary hyperparathyroidism /
- hungry bone syndrome /
- hypercalcium crisis

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图 1 放射性核素检查

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图 2 常规病理结果

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图 3 血钙变化曲线图

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图 4 PTH变化曲线图

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图 5 静脉补钙变化曲线图

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