The working principle and prototype construction of the Chinese vestibular prosthesis
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摘要: 目的 完成具有自主知识产权的国产人工前庭工作原理设计及原型机构建，并验证其工作性能，为人工前庭临床推广应用奠定基础。方法 在既往研究的基础上，以前庭神经系统信息编码原则为核心，构建国产多通道人工前庭的工作原理，并依据该原理进行电路设计；选择合适电子元器件以及软件系统，构建国产多通道人工前庭原型机；通过性能测试，验证该原型机的输入、输出特性。结果 成功设计了国产多通道人工前庭工作原理框图，并依据此框图进行了工作原理的详细阐明；依据工作原理，设计并绘制了国产多通道人工前庭电路图，并依据电路图布局将所选的电子元器件以及软件系统有机组合起来，完成国产多通道人工前庭原型机的构建；性能测试实验表明，国产多通道人工前庭原型机各个刺激电极能够输出双相脉冲电流，能够感知空间旋转运动并且依据旋转运动数据输入调制输出的脉冲电流频率。结论 国产多通道人工前庭工作原理及电路设计合理；国产多通道人工前庭原型机构建成功，空间旋转运动感知输入及调制脉冲电流输出稳定且可靠。Abstract: Objective To complete the working principle design and prototype construction of the Chinese multichannel vestibular prosthesis (CMVP) with independent intellectual property rights, and verify its working performance, so as to lay the foundation for the clinical promotion and application of CMVP.Methods On the basis of previous research, the working principle of CMVP was constructed based on the information encoding principle of vestibular nervous system, and the circuit was designed according to the principle. Then, appropriate electronic components and software systems were selected to construct a CMVP prototype according to the design. Finally, the input and output characteristics of the CMVP prototype were verified through the performance test.Results In the present study, a block diagram of the working principle of the CMVP was successfully designed and drawn, and the working principle was explained in detail according to the block diagram. Further, the circuit diagram of the CMVP was designed and drawn based on the working principle, then the selected electronic components and software systems were combined one by one to complete the construction of a prototype. Finally, the performance test for the prototype was completed, which showed that all stimulus electrodes of the prototype could output biphasic pulse current, and the frequency of biphasic pulse current was modulated by the spatial rotation data input sensed by a motion sensor.Conclusion The working principle and circuit design of the CMVP are reasonable; the CMVP prototype in China has been successfully constructed; the spatial rotation motion sensing input and the modulated pulse current output are stable and reliable.
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