The application value of video head impulse test, caloric test and dizziness handicap inventory in the diagnosis of acoustic neuroma
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摘要: 目的 探讨视频头脉冲试验(vHIT)、冷热试验(CT)和眩晕障碍程度评定量表(DHI)诊断听神经瘤(AN)的价值，分析vHIT和CT的相关性，并评估肿瘤大小与vHIT、CT和DHI评分的相关性。方法 回顾分析2019年1月—2022年1月接受手术治疗的24例AN患者临床资料，包括颅脑MRI、vHIT、CT及DHI评分，所有数据采用GraphPad Prism 9.0进行统计学分析。结果 CT的同侧半规管轻瘫(UW)值和vHIT的前庭眼反射(VOR)增益之间存在显著负相关(P < 0.01，r=-0.62)。肿瘤大小与CT的UW值增加呈显著相关(P < 0.01，r=0.69)，与vHIT的VOR增益减少存在相关性(P < 0.01，r=-0.53)。平均DHI评分为(8.9±16.2)分，与肿瘤大小差异无统计学意义(P>0.05)。结论 vHIT和CT均能有效评估AN患者的前庭功能，且具有互补性，均与肿瘤大小相关，对AN的诊断具有一定价值。Abstract: Objective To explore the application value of video head impulse test(vHIT), caloric test(CT) and the dizziness handicap inventory(DHI) in the diagnosis of acoustic neuroma(AN), to analyze the correlation between vHIT and CT, and to determine the correlationsof tumor size, vHIT, CT and DHI score.Methods The clinical data of 24 patients with AN who underwent surgery in our department from January 2019 to January 2022 were analyzed retrospectively, including craniocerebral MRI, vHIT, caloric test and DHI score. All the data were statistically analyzed by GraphPadPrism9.0.Results There was a significant negative correlation between the UW value of CT and the vestibular eye reflex gain of vHIT(P < 0.01, r=-0.62). The tumor size was significantly correlated with the increase of UW value of CT(P < 0.01, r=0.69), and with the decrease of vestibulo-ocular reflex gain of vHIT(P < 0.01, r=-0.53). The average Dizziness Handicap Inventory score was 8.9±16.2, which was not correlated with tumor size(P>0.05).Conclusion Both vHIT and CT can effectively evaluate the vestibular function of patients with AN(and they are complementary), and they are related to the size of the tumor and have certain value in the diagnosis of acoustic neuroma.
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Key words:
- acoustic neuroma /
- video head impulse test /
- caloric test /
- magnetic resonance imaging
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表 1 24例患者的临床资料
X ±S 临床资料 全部(24例) 肿瘤侧别 左侧 右侧 P值 男性/例(%) 12(50.0) 6(50.0) 6(50.0) > 0.99 年龄/岁 46.6±11.6 44.4±15.1 48.5±7.8 0.42 半规管轻瘫值/% 63.1±24.1 64.1±18.5 62.3±28.3 0.86 vHIT增益下降/例(%) 14(58.3) 6(54.5) 8(61.5) > 0.99 肿瘤大小/mm 22.7±1.0 21.8±8.4 23.4±11.5 0.7 DHI评分 8.9±16.2 7.5±11.8 10.2±19.6 0.69 
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