鼻黏膜温度变化与鼻气流感知之间的相关性研究进展

高翔; 武骏; 魏洪政; 徐文; 韩德民

doi:10.13201/j.issn.2096-7993.2022.05.017

鼻黏膜温度变化与鼻气流感知之间的相关性研究进展

- 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科耳鼻咽喉头颈科学教育部重点实验室(首都医科大学)(北京，100730)
基金项目:
国家自然科学基金(No：81970866)

详细信息

通讯作者: 韩德民，E-mail：enthandm@126.com

中图分类号: R765

收稿日期: 2021-07-30

刊出日期: 2022-05-03

Correlation between nasal mucosal temperature change and nasal airflow perception

- Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital and Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing, 100730, China

More Information

Corresponding author: HAN Demin, E-mail: enthandm@126.com

Received Date: 30 July 2021

Publish Date: 03 May 2022

摘要

摘要: 关于鼻气流感知的机制仍知之甚少，目前认为产生鼻腔通畅感的主要机制是激活鼻黏膜温度感受器瞬态受体电位M型家族成员8。计算流体力学研究表明，鼻腔增加的热流量与患者主观气流感知相关。同样，使用温度探头对鼻腔进行的物理测量显示较低的鼻黏膜温度与更好的气流感知之间存在相关性。三叉神经功能检测也间接证实了这一点。本研究旨在综述鼻黏膜温度变化在鼻腔通畅感知中的作用及其量化方法。
- 鼻气流感知 /
- 黏膜冷却 /
- 瞬态受体电位M型家族成员8 /
- 三叉神经
Abstract: The mechanism of nasal airflow perception remains little known. It is currently believed that the main mechanism for perceiving nasal patency is to activate transient receptor potential melastatin subtype 8. Computer fluent dynamics show that increased airflow and heat flux are associated with higher subjective scores. Similarly, physical measurements of the nasal cavity using a temperature probe show a correlation between the lower nasal mucosa temperature and better results. Trigeminal function detection also indirectly confirms this. This literature review aimed to explore the role of nasal mucosal temperature change in the subjective perception of nasal patency and the secondary aim was to appraise the relevant evidence about the mechanism.
- nasal flow perception /
- mucosal cooling /
- transient receptor potential melastatin subtype 8 /
- trigeminal nerve

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参考文献(50)

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