Quality of life survey of patients with allergic rhinitis caused by airborne pollen in Inner Mongolia
-
摘要: 目的 研究内蒙古地区气传花粉所致变应性鼻炎(AR)患者的生活质量水平,为今后对AR患者实施整体健康干预提供参考依据。方法 将268例AR患者根据病情严重程度分为轻度组和中重度组,采用一般状况调查表、标准化鼻结膜炎生存质量调查问卷(RQLQ)、生活质量核心简表(QOL-C30)评估AR患者的生活质量;同时选取90例无鼻症状的健康志愿者(均衡性别、年龄)作为对照组。结果 AR患者中重度组RQLQ问卷总评分及7个因子评分均较轻度组增高(均P < 0.05)。中重度组QOL-C30评估的4个维度得分与对照组比较均普遍降低(均P < 0.05);轻度组与对照组比较,躯体功能和心理功能得分降低明显(P < 0.05);中重度组与轻度组比较,躯体功能、心理功能和物质生活得分降低明显(P < 0.05)。结论 花粉作为气传变应原是内蒙古地区AR发病的主要诱因,AR会严重影响患者的身心健康,使生活质量下降。临床应注重为AR患者提供标准化治疗干预和良好健康教育从而改善生活质量。Abstract: Objective To study the quality of life of patients with allergic rhinitis(AR) caused by airborne pollen in Inner Mongolia, and provide reference for overall health intervention for AR patients.Method According to the severity of disease, 268 cases of patients was divided into mild and moderate to severe group. The patients general condition questionnaire, standardized rhinoconjunctivitis quality of life questionnaire(RQLQ), quality of life questionare-core30(QOL-C30) were used to assess the quality of life of AR patients. At the same time 90 healthy volunteers with no symptoms of nasal(balanced gender, age) were recruited as control group.Result In the intra-group comparison of the RQLQ questionnaire for AR patients, the total score of the RQLQ questionnaire and the 7 factor scores in the moderate to severe groups were significantly higher than those in the mild group(all P < 0.05). The QOL-C30 survey showed that the scores of the four dimensions of QOL-C30 assessment in the moderate to severe group of AR patients were generally lower than those in the control group(all P < 0.05). Compared with the control group, the score of physical function and psychological function in mild group decreased significantly(P < 0.05). Compared with the mild group, the moderate to severe groups showed significant decreases in physical function, psychological function and material life score(P < 0.05).Conclusion Pollen, as a airborne allergen, is the main inducement of AR in Inner Mongolia. AR can seriously affect the physical and mental health of patients and reduce the quality of life. Clinical practice should focus on providing standardized treatment interventions and good health education for AR patients to improve quality of life.
-
Key words:
- rhinitis, allergic /
- airborne pollen /
- quality of life
-
表 1 不同病情严重程度AR患者RQLQ评分比较
分,x±s RQLQ评分项目 轻度组
(n=104)中重度组
(n=164)日常活动 3.40±1.19 3.80±1.371) 睡眠 2.18±1.27 2.41±1.251) 非鼻/眼症状 1.92±1.45 2.35±1.571) 鼻炎相关行为 3.58±1.75 4.12±1.801) 鼻部症状 3.87±1.33 4.26±1.541) 眼部症状 2.76±1.25 3.27±1.181) 情感反应 2.04±1.26 2.57±1.461) 总评分 2.82±1.13 3.24±1.091) 与轻度组比较,1)P < 0.05。 表 2 AR组与对照组QOL-C30评分比较
分,x±s 组别 例数 QOL-C30评分 躯体功能 心理功能 社会功能 物质生活 轻度组 104 28.45±3.151) 21.92±2.571) 23.52±2.36 21.30±1.94 中重度组 164 22.32±2.141)2) 18.30±2.701)2) 22.41±2.391) 18.12±1.871)2) 对照组 90 35.67±3.57 29.41±3.26 24.76±2.19 22.81±2.44 与对照组比较,1)P < 0.05;与轻度组比较,2)P < 0.05。 -
[1] 韩娟. 变应性鼻炎患者心理状况及其与生活质量的相关性研究[J]. 中国耳鼻咽喉头颈外科, 2018, 25(4): 189-191. https://www.cnki.com.cn/Article/CJFDTOTAL-EBYT201804008.htm
[2] 何霞, 冯彦, 王斌全, 等. 变应性鼻炎健康相关生存质量测定常用量表简析[J]. 临床耳鼻咽喉头颈外科杂志, 2017, 31(1): 23-26. https://www.cnki.com.cn/Article/CJFDTOTAL-LCEH201701008.htm
[3] 靳彬, 詹引, 牟岚, 等. 健康质量测评方法研究[J]. 中国卫生质量管理, 2015, 22(3): 71-73. https://www.cnki.com.cn/Article/CJFDTOTAL-WSJG201503032.htm
[4] 王晓艳, 宁慧宇, 韩班布拉, 等. 草原地区气传花粉可诱发应变性鼻炎[J]. 基因组学与应用生物学, 2017, 36(7): 2793-2798. https://www.cnki.com.cn/Article/CJFDTOTAL-GXNB201707035.htm
[5] 李科琼, 李静, 张玲玲, 等. 变应性鼻炎患儿生存质量调查及其影响因素分析[J]. 中国全科医学, 2018, 21(18): 2216-2222. doi: 10.3969/j.issn.1007-9572.2018.00.161
[6] Kang IG, Ju YH, Jung JH, et al. The effect of PM10 on allergy symptoms in allergic rhinitis patientsduring spring season[J]. Int J Environ Res Public Health, 2015, 12(1): 735-745. doi: 10.3390/ijerph120100735
[7] Kim DH, Han K, Kim SW. Relationship Between Allergic Rhinitis and Mental Health in the General Korean Adult Population[J]. Allergy Asthma Immunol Res, 2016, 8(1): 49-54. doi: 10.4168/aair.2016.8.1.49
[8] Nathan RA. The burden of allergic rhinitis[J]. Allergy Asthma Proc, 2007, 28(1): 3-9. doi: 10.2500/aap.2007.28.2934
[9] 龙冬秋, 刘振, 程方祝. 持续性、中重度变应性鼻炎脱敏治疗前后的生活质量评估[J]. 中国医药指南, 2013, 11(17): 659-659. doi: 10.3969/j.issn.1671-8194.2013.17.506
[10] Sansone RA, Sansone LA. Allergic rhinitis: relationships with anxiety and mood syndromes[J]. Innov Clin Neurosci, 2011, 8(7): 12-17.
[11] 章娜娜, 陶泽璋, 邓玉琴, 等. 不同过敏原对变应性鼻炎患者症状及生活质量影响的比较[J]. 中华临床免疫和变态反应杂志, 2012, 6(1): 47-51. https://www.cnki.com.cn/Article/CJFDTOTAL-OZHL201201011.htm
[12] 刘萍, 郭杰峰, 吴郁丽, 等. 变应性鼻炎儿童的智力结构与个性特征分析[J]. 四川精神卫生, 2016, 29(2): 172-175. https://www.cnki.com.cn/Article/CJFDTOTAL-WANT201602023.htm