慢性鼻窦炎中金黄色葡萄球菌药敏结果分析

刘洋; 范立; 汤燕琴; 张志远

doi:10.13201/j.issn.1001-1781.2018.11.016

慢性鼻窦炎中金黄色葡萄球菌药敏结果分析

- 1. 抚州市第一人民医院耳鼻喉口腔科(江西抚州, 344000);
- 2. 南昌大学第一附属医院耳鼻咽喉头颈外科

详细信息

通讯作者: 张志远,E-mail:zzyent@126.com

中图分类号: R765.4

收稿日期: 2017-12-19

Analysis of drug sensitivity of Staphylococcus aureus in patients with chronic sinusitis

- 1. Department of ENT and Stomatology, First People's Hospital of Fuzhou, Fuzhou, 344000, China;
- 2. Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Nanchang University

More Information

Corresponding author: ZHANG Zhiyuan, E-mail: zzyent@126.com

Received Date: 19 December 2017

摘要

摘要: 目的：了解慢性鼻窦炎（CRS）及健康对照者鼻腔金黄色葡萄球菌感染情况及药物敏感性。方法：对71例CRS患者（实验组）和103例健康对照者（对照组）中鼻道分泌物行细菌培养和药敏试验，分析金黄色葡萄球菌感染情况及药物敏感性。结果：实验组71例患者中，分离出金黄色葡萄球菌29株，阳性率为40.85%；103例对照组中，分离出12株，阳性率为11.65%。菌株对氨基糖苷类、糖肽类药物敏感性较高，实验组与对照组耐药率无差异。共检出13株耐甲氧西林金黄色葡萄球菌，未出现对喹诺酮类、氨基糖苷类和万古霉素耐药的菌株。结论：部分CRS患者发病可能与金黄色葡萄球菌感染有关，使用抗生素治疗CRS，应根据鼻腔分泌物的细菌培养和药敏结果选择药物。
- 鼻窦炎 /
- 细菌培养 /
- 抗生素类
Abstract: Objective: To investigate the prevalence and drug sensitivity of nasal Staphylococcus aureus infection in patients with chronic sinusitis and healthy controls. Method: Bacterial culture and drug sensitivity test were performed in 71 patients with CRS (experimental group) and 103 healthy controls (control group). The infection rate of Staphylococcus aureus and the sensitivity of the drug were analyzed based on these results. Result: Twenty-nine Staphylococcus aureus strains were isolated from 71 cases of patients in the experimental group, and the positive rate was 40.85%; 12 Staphylococcus aureus strains were isolated from 103 cases of patients in the control group, and the positive rate was 11.65%. There was no significant difference between the experimental group and the control group in the sensitivity of the strains to aminoglycosides and glycopeptides. A total of 13 strains of methicillin-resistant Staphylococcus aureus (MRSA) were detected, and there was no strains which had resistance to quinolones, aminoglycosides and vancomycin. Conclusion: The incidence of CRS may be related to the infection of Staphylococcus aureus. The use of antibiotics in the treatment of CRS should be based on the results of bacterial culture and drug sensitivity test.
- sinusitis /
- bacterial culture /
- antibiotics

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