甲状旁腺激素水平在预测双侧甲状腺全切术后低血钙中的应用价值

张守鹏

doi:10.13201/j.issn.1001-1781.2016.01.011

甲状旁腺激素水平在预测双侧甲状腺全切术后低血钙中的应用价值

张守鹏^,

- 华中科技大学同济医学院附属协和医院乳腺甲状腺外科(武汉, 430022)

详细信息

通讯作者: 张守鹏,E-mail:zspzhangshoupeng@126.com

中图分类号: R582

收稿日期: 2015-09-11

The application value of parathyroid hormone level in predicting post-operative hypocalcemia after total thyroidectomy

ZHANG Shoupeng^,

- Department of Mammary Gland Thyroid Surgery, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

More Information

Corresponding author: ZHANG Shoupeng, E-mail: zspzhangshoupeng@126.com

Received Date: 11 September 2015

摘要

摘要: 目的:探讨甲状旁腺激素(PTH)水平在预测双侧甲状腺全切术后低血钙中的应用价值。方法:选择207例甲状腺全切患者,测定术后第1天晨血清PTH和电解质,根据术后低血钙定义分为无术后低血钙组和有术后低血钙组,并结合临床资料进行受试者工作曲线分析。结果:术前组间PTH均值差异无统计学意义(P>0.05);术后第1天,有术后低血钙组PTH均值均显著低于无术后低血钙组(P<0.01)。术后第1天受试者工作曲线下面积为0.886,PTH最佳诊断值为16.8 pg/ml。结论:术后24 h内PTH水平是判断甲状腺全切术后低血钙的重要指标。
- 甲状腺切除术 /
- 甲状旁腺激素 /
- 受试者工作曲线 /
- 低钙血症
Abstract: Objective:To investigate the application value of parathyroid hormone (PTH) within 24 hours in predicting post-operative hypocalcemia after total thyroidectomy.Method:In this study, we selected 207 consecutive patients, performed total thyroidectomy in our hospital, measured the serum PTH and electrolyte, divided them into subgroups according to the definition of post-operative hypocalcemia, and made the ROC curves analysis combining with clinical data.Result:The mean value of pre-operative PTHs between groups show no significant difference (P>0.05); in the first day after surgery, the post-operative hypocalcemia group have a significant lower average PTHs (P<0.01). ROC area under the curve (AUC) of day-1 is 0.886, with the PTH cutoff value 16.8 pg/ml.Conclusion:The PTH within 24 hours is an important indicator to judging post-operative hypocalcemia after total thyroidectomy.
- thyroidectomy /
- parathyroid hormone /
- receiver operating characteristic /
- hypocalcemia

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