喉非鳞状细胞癌恶性肿瘤的临床特点分析

谢华顺; 闫燕; 刘仲奇; 马芙蓉

doi:10.13201/j.issn.1001-1781.2015.17.009

喉非鳞状细胞癌恶性肿瘤的临床特点分析

- 北京大学第三医院耳鼻咽喉头颈外科(北京, 100191)

详细信息

通讯作者: 闫燕,E-mail:wzyyer34@163.com

中图分类号: R739.6

收稿日期: 2015-06-29

Clinical profile analysis of laryngeal nonsquamous cell malignancies

- Department of Otolaryngology-Head and Neck Surgery, the Third Hospital of Peking University, Beijing, 100191, China

More Information

Corresponding author: YAN Yan, E-mail: wzyyer34@163.com

Received Date: 29 June 2015

摘要

摘要: 目的:回顾性分析15例喉非鳞状细胞恶性肿瘤的临床特点,探讨该类疾病的诊断及治疗方法。方法:收集15例经病理确诊为喉非鳞状细胞恶性肿瘤患者的临床资料,分析其病理学、CT、治疗、随访结果等特点。结果:患者男女比例为4∶1;声门上型占53.33%(8/15)。 15例患者中,1例单纯行气管切开术缓解呼吸困难症状,放弃其他治疗;3例明确诊断后行放疗或化疗;其余患者根据病情行不同方式的手术切除,术后辅助放疗和(或)化疗。随访结果提示,1、3、5年生存率分别为79.4%、57.8%、27.5%,中位生存时间为42个月。结论:男性患者易罹患喉非鳞状细胞恶性肿瘤,其中以声门上型多见;其临床特点与喉鳞状细胞癌有差异,容易复发或转移;5年生存率不高,预后较差。
- 喉肿瘤 /
- 非鳞状细胞癌 /
- 治疗 /
- 预后
Abstract: Objective: To observe clinical characteristics of 15 cases of laryngeal nonsquamous malignancies.Method: The clinical data of 15 patients with laryngeal nonsquamous malignancies were collected. Details about pathology, CT, treatment and follow-up results were carefully taken into account.Result: There were more male patients than females while the sex ratio was 4:1. Supraglottic malignancies accounting for 53.33% seemed to be the most common type. In all the 15 patients, 1 patient gave up other treatment except tracheotomy to relieve laryngeal obstruction. Three patients took radiotherapy and chemotherapy. The rest patients underwent surgical procedure after strict endoscopic, radiologic staging. Radiotherapy and (or) chemotherapy were chosen after operation. The follow-up results show that 1 year survival rate was 79.4% and the 3 year survival rate was 57.8%, 5 year survival rate was 27.5% which was not optimistic.Conclusion: Being a kind of rare type laryngeal nonsquamous malignancies have difference clinical characteristics with laryngeal squamous cell carcinoma. Laryngeal nonsquamous cell carcinoma have much lower 5 year survival rate and are easier to suffer recurrence and metastasis compared with laryngeal squamous cell carcinoma.
- laryngeal neoplasms /
- nonsquamous cell carcinoma /
- therapy /
- prognosis

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参考文献(6)

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