安徽芜湖地区变应性鼻炎患儿家居环境尘螨变应原的分布特征及影响因素分析

纪东; 桂晓钟; 江万进; 王琴

doi:10.13201/j.issn.1001-1781.2015.05.007

安徽芜湖地区变应性鼻炎患儿家居环境尘螨变应原的分布特征及影响因素分析

- 1. 芜湖市第二人民医院耳鼻咽喉-头颈外科(安徽芜湖, 241000);
- 2. 皖南医学院

详细信息

通讯作者: 桂晓钟,E-mail:324916465@qq.com

中图分类号: R765.21

收稿日期: 2014-12-15

Distribution characteristics and influencing factors of children with allergic rhinitis in a domestic dust mites allergens content distribution characteristics and influencing factors

- 1 Department of Otolaryngology-Head and Neck Surgery, the Second People's Hospital of Wuhu, Wuhu, 241000, China;
- 2 Wannan Medical College

More Information

Corresponding author: GUI Xiaozhong, E-mail: 324916465@qq.com

Received Date: 15 December 2014

摘要

摘要: 目的: 研究安徽芜湖地区尘螨变应性鼻炎(AR)患儿家居环境内尘螨变应原的分布特征及影响因素。方法: 选取102例AR患儿为研究对象。采集患儿家中卧室及客厅地板、床垫、枕头、沙发等处表面灰尘,应用酶联免疫吸附法测定灰尘样本中粉尘螨第1组分变应原(Der f1)和屋尘螨第1组分变应原(Der p1)的含量,以中位数(最小值,最大值)表示尘螨变应原含量。结果: 采集的102份尘样中,患儿家内尘螨样本中Der f1和Der p1含量分别是2.66(0.03,26.63),3.48(0.03,33.68),Der f1含量显著少于Der p1,差异有统计学意义(P<0.05)。采集样本按市区及乡镇分类,分别有68例、34例,患儿家内尘螨样本中Der f1含量分别是2.91(0.31,26.63)和2.40(0.08,16.02),Der p1含量分别是4.28(0.03,20.77)、3.88(0.14,33.68),市区尘螨含量显著多于乡镇,差异有统计学意义(P<0.05)。采集样本按性别分类,男孩与女孩家中尘螨变应原含量差异无统计学意义(P>0.05)。结论: 安徽芜湖地区AR患儿家居环境中尘螨以Der p1为主,市区尘螨含量显著多于乡镇,加强尘螨变应原的健康教育,控制居室内尘螨变应原污染,尤其是市区,对于防治儿童AR等过敏性疾病有重要意义。
- 鼻炎 /
- 变应性 /
- 尘螨变应原
Abstract: Objective: To observe the household environment dust mites allergens content distribution characteristics and influence factors of children with allergic rhinitis to dust mites in Wuhu.Method: Collect the surface dust in bedroom and living room floor, mattresses, pillows, sofa of 102 children with allergic rhinitis families. Dust mite allergen components 1 (Der f1) and house dust mites allergens 1 components (Der p1) of the dust samples were determined by enzyme-linked immunosorbent assay (ELISA).Result: One hundred and twenty samples were collected. In a domestic dust mites samples, with a median of M (Min and Max) said dust mite allergen levels, Der f1 and Der p1 content was 2.66 (0.03, 26.63), 3.48 (0,03,33.68), respectively. Der f1 was significantly less than Der p1,and the difference was statistically significant (P<0.05). According to the classification of urban and township, there were 68 cases and 34 cases. Der f1 content in the samples was 2.91 (0.31, 26.63), 2.40 (0.08, 16.02),respectively. Der p1 content was 4.28 (0.03, 20.77), 3.88(0.14, 33.68), respectively. The dust mites content of urban was significantly more than that of villages and towns, the difference was statistically significant (P<0.05). Samples were also classified by gender.The dust mites allergens content in either boy's or girl's family were similar, there was no statistically significant difference (P> 0.05).Conclusion: The household dust mites of children allergic rhinitisin Wuhu area is given priority to with Der p1, and urban dust mites are significantly more than village's and town's. Enhancing health education, controlling dust mites allergens contamination inside the bedroom,especially urban areas, are positive differences for the prevention and treatment of allergic diseases such as allergic rhinitis in children.
- rhinitis /
- allergic /
- dust mites allergens

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