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摘要: 目的:通过检测鼻塞患者血小板平均体积(MPV),探讨鼻塞与MPV的相关性。方法:以40例行鼻腔手术的鼻塞患者为实验组,30例健康人为对照组,比较2组外周血中血小板计数(PLT)、MPV、血小板分布宽度(PDW)的水平。实验组患者行解除鼻塞手术3个月后再次检测MPV水平,比较术前及术后的差异。结果:PLT、MPV、PDW实验组与对照组分别为(215.0±47.5)×109/L、 (10.7±0.9)fL、(12.9±2.0)%及(237.8±46.2)×109/L、(10.3±0.8)fL、(12.0±1.3)%,2组比较均差异有统计学意义(均P<0.05)。实验组MPV术前[(10.7±0.7)fL]与术后[(10.4±0.6)fL]比较差异有统计学意义(P<0.05)。结论:鼻塞患者的MPV水平升高,解除鼻塞手术能使MPV水平降低。Abstract: Objective:High mean platelet volume (MPV) values are a risk factor for cardiovascular diseases. Our aim was to investigate the association between nasal obstructive disease and MPV value.Method:This study included 40 patients with nasal obstructive disease and 30 age-and sex-matched healthy subjects as controls.The levels of the number of platelets, MPV, platelet distribution width (PDW) were evaluated and compared in the two groups. Then the MPV was compared in the patients before and after operation in the study group.Result:Platelet count is significantly lower in the study group than the control group[(215.0±47.5)×109/L versus (237.8±46.2)×109/L]; MPV and PDW is significantly higher in the study group[(10.7±0.7)fL versus (10.3±0.8) fL];[(12.9±2.0)% versus (12.0±1.3)%].Comparing to preoperation, MPV values of the study group is significantly decreased after nasal obstructive operations[(10.7±0.7) fL versus (10.4±0.6)fL].Conclusion:MPV levels are elevated in patients with nasal obstructive disease,and can be decreased by nasal obstructive operation.
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Key words:
- nasal obstruction /
- mean platelet volume /
- treatment
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