鼻窦低分化神经内分泌癌6例临床分析

徐丽; 关兵; 彭新; 徐英; 王莹; 吴晶涛

doi:10.13201/j.issn.1001-1781.2013.05.008

鼻窦低分化神经内分泌癌6例临床分析

- 1 扬州大学临床医学院耳鼻咽喉-头颈外科(江苏扬州, 225001);
- 2 扬州大学临床医学院医学影像科

详细信息

通讯作者: 关兵,E-mail:aliceguan0685@sina.com

中图分类号: R739.6

收稿日期: 2012-10-06

Analysis on 6 cases with nasal neuroendocrine carcinoma

- 1 Department of Otorhinolaryngology-Head and Neck Surgery, Clinical College of Yangzhou University, Yangzhou, 225001, China;
- 2 Department of Medical Imaging, Clinical College of Yangzhou University

More Information

Corresponding author: GUAN Bing, E-mail: aliceguan0685@sina.com

Received Date: 06 October 2012

摘要

摘要: 目的: 探讨鼻窦低分化神经内分泌癌的临床特点,CT、MRI表现及治疗方法。方法: 回顾性分析6例鼻窦低分化神经内分泌癌患者的资料,术前常规行CT、MRI检查。1例筛窦大细胞癌患者病变累及颅内,直接转入肿瘤科放化疗;余5例患者均在全身麻醉下行鼻内镜下肿瘤切除术,术后行放化疗。结果: 病理报告示2例为大细胞型低分化神经内分泌癌,其余4例为小细胞型低分化神经内分泌癌。1例在肿瘤科治疗的患者现带瘤生存2个月,随访中。行手术治疗的5例患者中1例术后4个月复发死亡,1例失访,其余3例目前均未复发。结论: 鼻窦低分化神经内分泌癌虽表现为恶性,但早发现、早诊断及综合治疗是改善该病预后的重要方法及手段。病变范围较局限的鼻窦低分化神经内分泌癌鼻内镜下手术有效、安全、微创。
- 神经内分泌肿瘤 /
- 鼻窦 /
- 内镜术
Abstract: Objective: To investigate the clinical features,the CT, MRI features and therapeutic strategy of nasal neuroendocrine carcinoma(NEC).Method: A restrospective study was carried out on 6 cases of NEC. 2 were female and 4 were male. Routine preoperative CT and MRI examination were performed.In one case,the tumor had invaded the brain and then was treated in department of oncology. Five cases were undertaken tumor resection under nasal endoscope, and combined with postoperative chemoradiation therapy.Result: The postoperative pathological report of 1 cases was large cell type, the remaining 4 cases were small cell type. One case treated in department of oncology had lived for 2 month with tumor in his body.One cases relapsed and died at 4 month after postoperation,1 case was lost and 3 case did not relaps till now.Conclusion: NEC of paranasal sinuses is malignant, but early detection, early diagnosis and treatment can improve the prognosis of this disease.For limited lesion of NEC, nasal endoscopic operation is an effective, safe and minimally injury method.
- neuroendocrine carcinoma /
- nasal sinuses /
- endoscopy

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