鱼尾葵花粉过敏的变应性鼻炎患者中血清总IgE及特异性IgE结果的分析

姚敏; 孟光

doi:10.13201/j.issn.1001-1781.2013.02.012

鱼尾葵花粉过敏的变应性鼻炎患者中血清总IgE及特异性IgE结果的分析

姚敏^1, ,,
孟光²

- 1. 海口市人民医院检验科(海口, 570208);
- 2. 海口市人民医院耳鼻咽喉科
基金项目:
国家自然基金地区科学基金资助项目(No:81160129)

详细信息

通讯作者: 姚敏,E-mail:yaoruan@sina.com

中图分类号: R765.21

收稿日期: 2012-05-29

Analysis of total and specific IgE in serum of carvota mitis pollen-induced allergic rhinitis patients

YAO Min^1, ,,
MENG Guang²

- 1. Department of Laboratory Medicine, Haikou People′s Hospital, Haikou, 570208, China;
- 2. Department of Otorhinolaryngology, Haikou People′s Hospital

More Information

Corresponding author: YAO Min, E-mail: yaoruan@sina.com

Received Date: 29 May 2012

摘要

摘要: 目的:探讨鱼尾葵花粉过敏的变应性鼻炎(AR)患者中血清总IgE、特异性IgE和变应原皮肤试验之间的关系。方法:选择429例对鱼尾葵花粉过敏的AR患者为实验组,243例健康体检者为对照组。实验组进行皮肤试验和特异性IgE水平检测,鱼尾葵花粉特异性IgE采用BSA-ELISA法;所有个体均检测血清总IgE水平。结果:实验组血清总IgE的阳性率明显高于对照组的阳性率(分别为66.2%和15.6%,P<0.01);实验组皮肤试验与血清特异性IgE之间差异无统计学意义(χ²=0.758 8,P>0.05);实验组血清特异性IgE和总IgE之间差异有统计学意义(χ2=50.639,P<0.01);海口长居患者与来海南旅游过客血清特异性IgE之间、总IgE之间差异均无统计学意义(P>0.05)。结论:变应原皮肤试验与检测鱼尾葵花粉特异性IgE 2种方法在诊断鱼尾葵花粉过敏的AR中有重要作用,检测血清总IgE对鱼尾葵花粉过敏的AR患者的诊断有参考价值,鱼尾葵花粉过敏的AR患者IgE的阳性率与接触时间之间的关系,有待进一步研究。
- 鱼尾葵花粉 /
- 鼻炎 /
- 变应性 /
- 皮肤试验 /
- IgE
Abstract: Objective:Exploring the relationship between total and specific IgE in serum and allergen skin test of carvota mitis pollen-induced allergic rhinitis patients.Method:Four hundred and twenty-nine carvota mitis pollen-induced allergic rhinitis patients and 243 healthy control subjects were recruited.The experimental group carried out skin tests.and pollen-specific IgE were also examined by BSA-ELISA method.Total IgE in serum of all of the subjects were determined by ELISA.Result:The positive rate of the total IgE level of the patients were much higher than those of the controls(66.2% vs.15.6%,P<0.01).No statistically significance was found between the positivity of skin test and serum specific IgE of the experimental group(χ²=0.758 8,P>0.05).The difference between serum-specific IgE and total IgE was statistically significant(χ²=50.639,P<0.01).There was no statistical significance of specific IgE and the total IgE in serum between long term residents in Haikou and Hainan Tourisms(P>0.05).Conclusion:Allergen skin test and carvota mitis pollen-specific IgE are two effective methods for the diagnosis of carvota mitis pollen-induced allergic rhinitis.The detection of total IgE in serum of carvota mitis pollen-induced allergic rhinitis provides a reference value for diagnosis.The relationship between concentration of IgE in serum of the carvota mitis pollen-induced allergic rhinitis and allergen contact duration is waiting for further study.
- carvota mitis polen /
- rhinitis /
- allergic /
- skin tests /
- IgE

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