再生医学之鼻软骨组织工程研究进展

李雪盛; 孙建军

doi:10.13201/j.issn.1001-1781.2019.12.027

再生医学之鼻软骨组织工程研究进展

李雪盛,
孙建军^,

- 解放军总医院第六医学中心全军耳鼻咽喉头颈外科中心(北京, 100048)

详细信息

通讯作者: 孙建军,E-mail:jjsun85@sina.com

中图分类号: R765

收稿日期: 2019-08-23

Regenerative medicine: the research progress of cartilage tissue engineering in rhinology

More Information

Corresponding author: , E-mail: jjsun85@sina.com

Received Date: 23 August 2019

摘要

摘要: 组织工程技术是再生医学的重要分支,它是采用生物相容性支架和特定种子细胞,来恢复或重建受损组织器官的正常功能^[1]。生物支架材料除了为组织细胞提供适宜的生长环境外,还是多种生长因子的载体,营造适合细胞生长和分化的微环境。理想的组织工程支架材料应具有生物相容性、生物可降解性以及适当的力学特性,并易于获得、适用于临床。1鼻软骨组织工程应用范围该技术可用于多种鼻科疾病的治疗,包括先天性和后天性软骨缺损,如先天性唇腭裂引起的鼻畸
- 软骨 /
- 组织工程 /
- 鼻科学 /
- 再生医学
Abstract: In recent years, the cartilage tissue engineering technology has rapid development, and shows a bright prospect in the field of cartilage defect and repair. In this paper, the field of rhinology cartilage tissue engineering research progress were reviewed, with the purpose to understand the status quo, and determine the next step research direction. From the research in recent years, we found that although cartilage tissue engineering technique could play an important role in the field of rhinology, but the progress to date was still lagging behind. In the published literature, there were few basic and applied research about cartilage tissue engineering techniques for nasal diseases. There have a small amount of applied research report, mainly concentrated in the animal experiments. There are still quite a distance from a wide range of clinical application. Based on the existing research results, cartilage tissue engineering technique in nasal plastic and reconstruction surgery has great potential in clinic application and needs more further research.
- cartilage /
- tissue engineering /
- rhinology /
- regenerative medicine

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参考文献(23)

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