-
摘要: 眩晕是临床上常见的主观症状,其客观表现为平衡失调,具体临床表现纷繁复杂。近年来,眩晕疾病的研究得到多学科的关注,先后完善了一系列常见眩晕疾病如BPPV、前庭性偏头痛、梅尼埃病以及持续性姿势-知觉性头晕综合征的指南或共识,这对眩晕的临床工作有着重要的指导作用。但是目前对眩晕疾病的病因、发病机制、治疗等尚未完全明晰,临床中常常遇到伴有睡眠障碍的眩晕患者,其关系也有相关研究,现从两者的流行病学、可能机制、相关临床研究以及治疗方法的选择几个方面进行综述。Abstract: Sleep disorders are commonly encountered in patients with vertigo. Comorbid of them is a major clinical challenge as the outcomes of both conditions are worsened by each other. The sleep and vertigo issues that are covered in this review are epidemiology, possible mechanisms and pathogenesis, and most recent clinical studies. In addition, treatment recommendations on vertigo patients with sleep disorders are discussed briefly. The multiple interactions between vertigo and sleep disorders underscore the need for improving the ability to deal with comorbidity.
-
Key words:
- dizziness /
- vertigo /
- sleep disorders
-
-
[1] NEUHAUSER H K.The epidemiology of dizziness and vertigo[J].Handb Clin Neurol,2016,137:67-82.
[2] CIORBA A,BIANCHINI C,SCANELLI G,et al.The impact of dizziness on quality-of-life in the elderly[J].Eur Arch Otorhinolaryngol,2017,274:1245-1250.
[3] KROENKE K,HOFFMAN R M,EINSTADTER D.How Common Are Various Causes of Dizziness?A Critical Review[J].South Med J,2000,93:160-167.
[4] ARYA A K,NUNEZ D A.What proportion of patients referred to an otolaryngology vertigo clinic have an otological cause for their symptoms?[J].J Laryngol Otol,2008,122:145-149.
[5] GOTO F,TSUTUMI T,ARAI M,et al.Somatic symptoms in those hospitalized for dizziness or vertigo[J].Nihon Jibiinkoka Gakkai Kaiho,2010,113:742-750.
[6] MINER B,KRYGER M H.Sleep in the Aging Population[J].Sleep Med Clin,2017,12:31-38.
[7] DOI Y,MINOWA M,OKAWA M,et al.Prevalence of sleep disturbance and hypnotic medication use in relation to sociodemographic factors in the general Japanese adult population[J].J Epidemiol,2000,10:79-86.
[8] MURAKAMI D M,ERKMAN L,HERMANSON O,et al.Evidence for vestibular regulation of autonomic functions in a mouse genetic model[J].Proc Natl Acad Sci U S A,2002,99:17078-17082.
[9] FULLER P M,JONES T A,JONES S M,et al.Evidence for macular gravity receptor modulation of hypothalamic,limbic and autonomic nuclei[J].Neuroscience,2004,129:461-471.
[10] MARTIN T,MAUVIEUX B,BULLA J,et al.Vestibular loss disrupts daily rhythm in rats[J].J Appl Physiol,2015,118:310-318.
[11] HOROWITZ S S,BLANCHARD J H,MORIN L P.Intergeniculate leaflet and ventral lateral geniculate nucleus afferent connections:An anatomical substrate for functional input from the vestibulo-visuomotor system[J].J Comp Neurol,2004,474:227-245.
[12] DRUMMOND S P A,GILLIN J C,BROWN G G.Increased cerebral response during a divided attention task following sleep deprivation[J].J Sleep Res,2001,10:85-92.
[13] MARTIN T,MOUSSAY,SÉBASTIEN,BULLA I,et al.Exploration of Circadian Rhythms in Patients with Bilateral Vestibular Loss[J].PLoS One,2016,11:e0155067.
[14] AITKEN P,BENOIT A,ZHENG Y,et al.Hippocampal and striatal M1-muscarinic acetylcholine receptors are down-regulated following bilateral vestibular loss in rats[J].Hippocampus,2016,26:1509-1514.
[15] BALABHADRAPATRUNI S,ZHENG Y,NAPPER R,et al.Basal dendritic length is reduced in the rat hippocampus following bilateral vestibular deafferentation[J].Neurobiol Learn Mem,2016,131:56-60.
[16] SOWERBY L J,ROTENBERG B,BRINE M,et al.Sleep apnea,daytime somnolence,and idiopathic dizziness—a novelassociation[J].Laryngoscope,2010,120:1274-1278.
[17] KONOMI U,SUZUKI M,OGAWA Y,et al.Assessment of sleep disturbance using the Pittsburgh Sleep Quality Index in patients with dizziness[J].Equilibrium Res,2014,73:502-511.
[18] SUGAYA N,ARAI M,GOTO F.The effect of sleep disturbance in patients with chronic dizziness[J].Acta Otolaryngol,2017,137:47-52.
[19] KIM S K,KIM J H,JEON S S,et al.Relationship between sleep quality and dizziness[J].PLoS One,2018,13:e0192705.
[20] ALBATHI M,AGRAWAL Y.Vestibular vertigo is associated with abnormal sleep duration[J].J Vestib Res,2017,27:127-135.
[21] LIN B Y,YOUNG Y H.Effect of short-duration sleep deprivation on the vestibulo-ocular reflex system evaluated by ocular vestibular-evoked myogenic potential test[J].Acta Otolaryngol,2014,134:698-703.
[22] KAYABASI S,IRIZ A,CAYONU M,et al.Vestibular functions were found to be impaired in patients with moderate-to-severe obstructive sleep apnea[J].Laryngoscope,2015,125:1244-1248.
[23] GALLINA S,DISPENZA F,KULAMARVA G,et al.Obstructive sleep apnoea syndrome(OSAS):effects on the vestibular system[J].Acta Otorhinolaryngol Ital,2010,30:281-284.
[24] NAKAYAMA M,SUZUKI M,INAGAKI A,et al.Impaired quality of sleep in Meniere's disease patients[J].J Clin Sleep Med,2010,6:445-449.
[25] NAKAYAMA M,KABAYA K.Obstructive sleep apnea syndrome as a novel cause for Meniere's disease[J].Curr Opin Otolaryngol Head Neck Surg,2013,21:503-508.
[26] 朱思翔,彭本刚.睡眠障碍对良性阵发性位置性眩晕治疗效果的影响[J].中华耳科学杂志,2016,14(4):549-550.
[27] ICHIJO H.Onset time of benign paroxysmal positional vertigo[J].Acta Otolaryngol,2017,137:144-148.
[28] SUGAYA N,ARAI M,GOTO F.The effect of vestibular rehabilitation on sleep disturbance in patients with chronic dizziness[J].Acta Otolaryngol,2017,137:275-278.
[29] EDELMAN S,MAHONEY A E,CREMER P D.Cognitive behavior therapy for chronic subjective dizziness:a randomized,controlled trial[J].Am J Otolaryngol,2012,33:395-401.
[30] TRAUER J M,QIAN M Y,DOYLE J S,et al.Cognitive Behavioral Therapy for Chronic Insomnia:A Systematic Review and Meta-analysis[J].Ann Intern Med,2015,163:191-204.
[31] CIPRIANI G,LUCETTI C,DANTI S,et al.Sleep disturbances and dementia[J].Psychogeriatrics,2015,15:65-74.
[32] 王晶,李晓燕,吴飞凤,等.持续正压通气治疗头晕的临床疗效分析[J].临床耳鼻咽喉头颈外科杂志,2016,30(8):609-612.
[33] SPENCE D W,KAYUMOV L,CHEN A,et al.Acupuncture increases nocturnal melatonin secretion and reduces insomnia and anxiety:a preliminary report[J].J Neuropsychiatry Clin Neurosci,2004,16:19-28.
[34] YIN X,GOU M,XU J,et al.Efficacy and safety of acupuncture treatment on primary insomnia:a randomized controlled trial[J].Sleep Med,2017,37:193-200.
[35] HOU Z,XU S,LI Q,et al.The Efficacy of Acupuncture for the Treatment of Cervical Vertigo:A Systematic Review and Meta-Analysis[J].Evid Based Complement Alternat Med,2017,2017:7597363.
-
计量
- 文章访问数: 1743
- PDF下载数: 995
- 施引文献: 0