儿童迟发型先天性中枢性低通气综合征2例

仇书要; 杨李强; 钟建文; 罗向前; 刘大波

doi:10.13201/j.issn.2096-7993.2023.08.011

儿童迟发型先天性中枢性低通气综合征2例

- 南方医科大学深圳医院儿童耳鼻咽喉科(广东深圳，518000)

详细信息

通讯作者: 刘大波，E-mail：daboliu@126.com

中图分类号: R725.6

收稿日期: 2023-06-07

刊出日期: 2023-08-03

Two children with late-onset congenital central hypoventilation syndrome

- Pediatric Otolaryngology Department of Shenzhen Hospital, Southern Medical University, Shenzhen, 518000, China

More Information

Corresponding author: LIU Dabo, E-mail: daboliu@126.com

Received Date: 07 June 2023

Publish Date: 03 August 2023

摘要

摘要: 报道2例确诊为迟发型先天性中枢性低通气综合征患儿，其中1例为男性，出生后无异常，1岁6个月时出现呼吸衰竭表现，住院后予吸氧和无创辅助通气治疗，CO₂潴留不能纠正，气管插管呼吸机通气1个月，未能成功拔管，逐行气管切开术，患儿睡眠时需要呼吸机辅助呼吸，清醒时经气管套管自主呼吸。另1例为女性，出生后无异常，11个月时出现呼吸衰竭表现，患儿睡眠时需要经鼻面罩无创辅助通气，白天自主呼吸，活动正常。2例患儿随访2年后生长发育正常。
- 中枢性低通气 /
- 先天性 /
- 儿童, 无创辅助通气 /
Abstract: Two children with late-onset congenital central hypoventilation syndrome were reported, one of whom was male and had no abnormal manifestations after birth, respiratory failure occurs at the age of 1 year and 6 months. After being hospitalized, he was treated with oxygen inhalation and non-invasive ventilation, but carbon dioxide retention could not be corrected. After one month of tracheal intubation, he was failure to wean from ventilator, so tracheostomy was performed. He needs a ventilator to help breath while sleeping, and can breath autonomously during the day without ventilator. The other case was a female, with no abnormalities after birth. At the age of 11 months, she developed respiratory failure. During sleep, the child needs non-invasive assisted ventilation through a nasal mask, and during the day, she breathed autonomously.Two patients were followed up forever 2 years and their growth and development were normal.
- central hypoventilation /
- congenital /
- children /
- non-invasive ventilation

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参考文献(17)

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