咽喉反流性疾病诊断量表的应用进展

韩悦; 张森; 皇甫辉; 刘晨阳; 严晨旭

doi:10.13201/j.issn.2096-7993.2023.04.016

咽喉反流性疾病诊断量表的应用进展

- 山西医科大学第一临床医学院山西医科大学第一医院耳鼻咽喉头颈外科(太原，030001)
基金项目:
山西医科大学博士启动基金资助项目(No: 03201628); 山西省基础研究计划自然科学基金(No: 20210302123250)

详细信息

通讯作者: 张森，E-mail：cccsl@sxmu.edu.cn

中图分类号: R766.5

收稿日期: 2022-04-28

刊出日期: 2023-04-03

The application progress on diagnostic scales of laryngopharyngeal reflux disease

- The First Clinical College of Shanxi Medical University; Department of Otorhinolaryngology Head and Neck Surgery, the First Hospital of Shanxi Medical University, Taiyuan, 030001, China

More Information

Corresponding author: ZHANG Sen, E-mail: cccsl@sxmu.edu.cn

Received Date: 28 April 2022

Publish Date: 03 April 2023

摘要

摘要: 目前对于咽喉反流性疾病(LPRD)的诊断缺乏微创、有效且经济的客观检测方法，诊断量表因其廉价、无创、易于操作等优势，在世界范围内得到广泛应用。临床应用最广泛的量表为反流症状指数(RSI)及反流体征评分(RFS)量表。近年来，RSI、RFS量表在应用中尚存在争议，对医务工作者诊断LPRD造成诸多困扰。因此，本文综述了RSI、RFS量表临床应用中的问题，并对其展开讨论，为医务工作者及相关研究人员准确诊断LPRD提供参考。
- 咽喉反流性疾病 /
- 诊断 /
- 反流症状指数 /
- 反流体征评分
Abstract: At present, objective methods for diagnosing laryngopharyngeal reflux disease(LPRD) are not minimally invasive, effective, and economical. Diagnostic scales are widely used worldwide due to the advantages of inexpensive, non-invasive, and easy to operate. The reflux symptom index(RSI) and the reflux finding score(RFS) are preferred to use in clinical diagnosis. However, many controversies have appeared in the application of RSI and RFS in recent years, causing many troubles to clinical diagnosis. Therefore, this review briefly discusses the problems of RSI and RFS in clinical applications to provide reference for diagnosing LPRD accurately.
- laryngopharyngeal reflux disease /
- diagnosis /
- reflux symptom index /
- reflux finding score

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参考文献(41)

[1]	李进让, 肖水芳, 李湘平, 等. 咽喉反流性疾病诊断与治疗专家共识(2015年)[J]. 中华耳鼻咽喉头颈外科杂志, 2016, 51(5): 324-326. doi: 10.3760/cma.j.issn.1673-0860.2016.05.002
[2]	Xiao S, Li J, Zheng H, et al. An epidemiological survey of laryngopharyngeal reflux disease at the otorhinolaryngology-head and neck surgery clinics in China[J]. Eur Arch Otorhinolaryngol, 2020, 277(10): 2829-2838. doi: 10.1007/s00405-020-06045-0
[3]	Belafsky PC, Postma GN, Koufman JA. The validity and reliability of the reflux finding score(RFS)[J]. Laryngoscope, 2001, 111(8): 1313-1317. doi: 10.1097/00005537-200108000-00001
[4]	Belafsky PC, Postma GN, Koufman JA. Validity and reliability of the reflux symptom index(RSI)[J]. J Voice, 2002, 16(2): 274-277. doi: 10.1016/S0892-1997(02)00097-8
[5]	李进让, Peter C. Belafsky, 张立红. 中国喉科医师应用反流体征评分量表的信度研究[J]. 中国耳鼻咽喉头颈外科, 2012, 19(7): 388-390. doi: 10.16066/j.1672-7002.2012.07.017
[6]	郑杰元, 张立红, 李晶兢, 等. 咽喉反流症状指数量表中文版的信度及效度评价[J]. 中华耳鼻咽喉头颈外科杂志, 2012(11): 894-898. doi: 10.3760/cma.j.issn.1673-0860.2012.11.004
[7]	Li J, Zhang L, Zhang C, et al. Linguistic Adaptation, Reliability, Validation, and Responsivity of the Chinese Version of Reflux Symptom Index[J]. J Voice, 2016, 30(1): 104-108. doi: 10.1016/j.jvoice.2013.12.006
[8]	Wang JY, Peng T, Zhao LL, et al. Poor consistency between reflux symptom index and laryngopharyngeal pH monitoring in laryngopharyngeal reflux diagnosis in Chinese population[J]. Ann Transl Med, 2021, 9(1): 25. doi: 10.21037/atm-20-4783
[9]	Chang BA, MacNeil SD, Morrison MD, et al. The Reliability of the Reflux Finding Score Among General Otolaryngologists[J]. J Voice, 2015, 29(5): 572-577. doi: 10.1016/j.jvoice.2014.10.009
[10]	彭雨婷, 徐丹, 刘雪莱, 等. 重庆地区耳鼻咽喉头颈外科门诊咽喉反流性疾病的流行病学调查[J]. 临床耳鼻咽喉头颈外科杂志, 2021, 35(4): 351-354. doi: 10.13201/j.issn.2096-7993.2021.04.015 https://lceh.whuhzzs.com/article/doi/10.13201/j.issn.2096-7993.2021.04.015
[11]	Nacci A, Bastiani L, Barillari MR, et al. Assessment and Diagnostic Accuracy Evaluation of the Reflux Symptom Index(RSI)Scale: Psychometric Properties using Optimal Scaling Techniques[J]. Ann Otol Rhinol Laryngol, 2020, 129(10): 1020-1029. doi: 10.1177/0003489420930034
[12]	Lechien JR, Mouawad F, Bobin F, et al. Review of management of laryngopharyngeal reflux disease[J]. Eur Ann Otorhinolaryngol Head Neck Dis, 2021, 138(4): 257-267. doi: 10.1016/j.anorl.2020.11.002
[13]	Vance D, Alnouri G, Shah P, et al. The Validity and Reliability of the Reflux Finding Score[J]. J Voice, 2023, 37(1): 92-96. doi: 10.1016/j.jvoice.2020.11.008
[14]	Nayak A, Kumar S, Arora R, et al. Image analysis of interarytenoid area to detect cases of Laryngopharyngeal Reflux: An objective method[J]. Am J Otolaryngol, 2018, 39(2): 171-174. doi: 10.1016/j.amjoto.2017.11.012
[15]	Chen M, Hou C, Chen T, et al. Reflux symptom index and reflux finding score in 91 asymptomatic volunteers[J]. Acta Otolaryngol, 2018, 138(7): 659-663. doi: 10.1080/00016489.2018.1436768
[16]	Włodarczyk E, Miaśkiewicz B, Raj-Koziak D, et al. The application of 24-hour pharyngeal pH-monitoring and Reflux Finding Score and Reflux Symptom Index questionnaires in the diagnostics of laryngopharyngeal reflux[J]. Prz Gastroenterol, 2019, 14(4): 274-282.
[17]	Venkatesan NN, Pine HS, Underbrink M. Laryngopharyngeal reflux disease in children[J]. Pediatr Clin North Am, 2013, 60(4): 865-878. doi: 10.1016/j.pcl.2013.04.011
[18]	Simons JP, Rosen CA, Casselbrant ML, et al. Comparison of Pediatric Voice Outcome Survey, Reflux Symptom Index, Reflux Finding Score, and esophageal biopsy results[J]. Arch Otolaryngol Head Neck Surg, 2008, 134(8): 837-841. doi: 10.1001/archotol.134.8.837
[19]	何畅. RSI及RFS评分表在学龄前儿童咽喉反流性疾病诊断中的意义的初步探讨[D]. 中国医科大学, 2018.
[20]	van der Pol RJ, Singendonk MM, König AM, et al. Development of the reflux finding score for infants and its observer agreement[J]. J Pediatr, 2014, 165(3): 479-484. doi: 10.1016/j.jpeds.2014.05.022
[21]	张军梅, 沈蓓. 咽喉反流性疾病在儿童的诊断与治疗[J]. 中国中西医结合耳鼻咽喉科杂志, 2022, 30(1): 73-76. https://www.cnki.com.cn/Article/CJFDTOTAL-XYJH202201018.htm
[22]	Lechien JR, Huet K, Khalife M, et al. Gender differences in the presentation of dysphonia related to laryngopharyngeal reflux disease: a case-control study[J]. Eur Arch Otorhinolaryngol, 2018, 275(6): 1513-1524. doi: 10.1007/s00405-018-4951-2
[23]	Lechien JR, Finck C, Huet K, et al. Voice Quality as Therapeutic Outcome in Laryngopharyngeal Reflux Disease: A Prospective Cohort Study[J]. J Voice, 2020, 34(1): 112-120. doi: 10.1016/j.jvoice.2018.08.018
[24]	王丽萍, 高远, 杨静, 等. 老年喉形态学改变与嗓音变化之间的关系[J]. 中华耳鼻咽喉头颈外科杂志, 2006, 41(9): 657-660. doi: 10.3760/j.issn:1673-0860.2006.09.005
[25]	Calvo-Henríquez C, Ruano-Ravina A, Vaamonde P, et al. Translation and Validation of the Reflux Symptom Index to Spanish[J]. J Voice, 2019, 33(5): 807. e1-807. e5.
[26]	Cervera-Paz FJ, Jordano-Cabrera M. Characterisation of laryngo-pharyngeal reflux disease in old and ageing patients[J]. Acta Otorrinolaringol Esp(Engl Ed), 2019, 70(3): 151-157. doi: 10.1016/j.otorri.2018.05.002
[27]	齐智伟, 张宇丽, 苏锐锋, 等. 年龄对反流症状指数量表和反流体征指数量表评分诊断咽喉反流的影响[J]. 临床耳鼻咽喉头颈外科杂志, 2020, 34(2): 170-172. doi: 10.13201/j.issn.1001-1781.2020.02.017 https://lceh.whuhzzs.com/article/doi/10.13201/j.issn.1001-1781.2020.02.017
[28]	Yamauchi A, Yokonishi H, Imagawa H, et al. Age-and gender-related difference of vocal fold vibration and glottal configuration in normal speakers: analysis with glottal area waveform[J]. J Voice, 2014, 28(5): 525-531. doi: 10.1016/j.jvoice.2014.01.016
[29]	Zhukhovitskaya A, Battaglia D, Khosla SM, et al. Gender and age in benign vocal fold lesions[J]. Laryngoscope, 2015, 125(1): 191-196. doi: 10.1002/lary.24911
[30]	Gao CK, Li YF, Wang L, et al. Different cutoffs of the reflux finding score for diagnosing laryngopharyngeal reflux disease should be used for different genders[J]. Acta Otolaryngol, 2018, 138(9): 848-854. doi: 10.1080/00016489.2018.1473642
[31]	Hutnik R, Zlatopolsky A, Mehraban-Far S, et al. Laryngopharyngeal reflux: Comparing improvements in reflux symptom index with reflux finding score[J]. Am J Otolaryngol, 2020, 41(6): 102730. doi: 10.1016/j.amjoto.2020.102730
[32]	Kavookjian H, Irwin T, Garnett JD, et al. The Reflux Symptom Index and Symptom Overlap in Dysphonic Patients[J]. Laryngoscope, 2020, 130(11): 2631-2636. doi: 10.1002/lary.28506
[33]	张青青, 谢萌, 郭瑞昕, 等. 质子泵抑制剂对咽喉反流患者唾液胃蛋白酶浓度的影响[J]. 临床耳鼻咽喉头颈外科杂志, 2021, 35(11): 965-970. doi: 10.13201/j.issn.2096-7993.2021.11.002 https://lceh.whuhzzs.com/article/doi/10.13201/j.issn.2096-7993.2021.11.002
[34]	王刚, 吴玮, 王磊, 等. Ryan指数与反流症状指数量表、反流体征量表在咽喉反流性疾病诊断中的相关性分析[J]. 山东大学耳鼻喉眼学报, 2018, 32(4): 48-52. https://www.cnki.com.cn/Article/CJFDTOTAL-SDYU201804011.htm
[35]	Lechien JR, Rodriguez Ruiz A, Dequanter D, et al. Validity and Reliability of the Reflux Sign Assessment[J]. Ann Otol Rhinol Laryngol, 2020, 129(4): 313-325. doi: 10.1177/0003489419888947
[36]	Lechien JR, Saussez S, Schindler A, et al. Clinical outcomes of laryngopharyngeal reflux treatment: A systematic review and meta-analysis[J]. Laryngoscope, 2019, 129(5): 1174-1187. doi: 10.1002/lary.27591
[37]	Lechien JR, Schindler A, Hamdan AL, et al. The development of new clinical instruments in laryngopharyngeal reflux disease: The international project of young otolaryngologists of the International Federation of Oto-rhino-laryngological Societies[J]. Eur Ann Otorhinolaryngol Head Neck Dis, 2018, 135(5S): S85-S91. https://www.sciencedirect.com/science/article/pii/S1879729618301236
[38]	Lechien J R, Bobin F, Muls V, et al. Validity and reliability of the reflux symptom score[J]. Laryngoscope, 2020, 130(3): E98-E107.
[39]	Min HK, Jeon SY, Lechien JR, et al. Translation and validation of the Korean Version of the Reflux Symptom Score[J]. J Voice, 2021.
[40]	Lin WJ, Wang CC, Chen SH, et al. Reflux Symptom Score and Quality of Life: Response to the Paper by Lechien JR et al[J]. Laryngoscope, 2021, 131(1): E203.
[41]	Lechien JR, Bobin F, Rodriguez A, et al. Development and Validation of the Short Version of the Reflux Symptom Score: Reflux Symptom Score-12[J]. Otolaryngol Head Neck Surg, 2021, 164(1): 166-174.