Tinnitus and depression after cochlear implantation in adult sensorineural deafness
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摘要: 目的 探讨成人重度、极重度耳聋患者耳蜗植入术(CI)后耳鸣和抑郁状态的变化及其相关性。方法 回顾性选择166例行CI的成人患者作为研究对象，所有患者手术前后均接受中文版耳鸣残疾评估量表(THI-C)调查和贝克抑郁量表第2版中文版(BDI-Ⅱ-C)调查，观察患者术后耳鸣改善情况、手术前后THI-C和BDI-Ⅱ-C得分情况以及两者之间的相关性。结果 CI术后6个月复查，患者手术前后耳鸣残疾评估等级显著下降(Z=-9.478，P < 0.001)，THI-C评分(t=69.128，P < 0.001)、BDI-Ⅱ-C评分(t=58.531，P < 0.01)均显著降低。Spearman相关性分析显示，手术前、后THI-C和BDI-Ⅱ-C评分之间以及THI-C评分改善程度和BDI-Ⅱ-C评分改善程度之间均具有显著正相关性(r术前=0.763、r术后=0.741、r差值=0.741，均P < 0.001)。结论 CI能显著改善成人感音神经性聋患者的耳鸣和抑郁程度。随着耳鸣程度的改善，患者抑郁状态也得以相应缓解。
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关键词:
- 听觉丧失，感音神经性 /
- 耳蜗植入术 /
- 耳鸣 /
- 抑郁
Abstract: Objective The aim of this study is to investigate the changes and correlation of tinnitus and depression in adult patients with severe deafness after cochlear implantation.Methods A total of 166 adult patients who underwent cochlear implantation(CI) were retrospectively selected as the research objects. All patients were investigated by Chinese Version of the Tinnitus Handicap Inventory(THI-C) and Chinese Version of the Beck Depression Inventory-Ⅱ(BDI-Ⅱ-C) before and after operation, and the improvement of tinnitus after operation was observed THI-C and BDI-Ⅱ-C scores before and after operation and the correlation between them.Results Re-examination at 6 months after CI showed that the evaluation grade of tinnitus disability before and after the operation decreased significantly(Z=-9.478, P < 0.001), and the THI-C score (t=69.128, P < 0.001), and BDI-Ⅱ-C score (t=58.531, P < 0.01)were significantly reduced. Spearman correlation analysis showed that there was a significant positive correlation between THI-C and BDI-Ⅱ-C scores before and after operation, aswell as the improvement of THI-C score and BDI-Ⅱ-C score(rpreoperative=0.763, rpostoperative=0.741, rdifference=0.741, all P < 0.001).Conclusion Cochlear implantation can significantly improve tinnitus and depression in adult patients with sensorineural hearing loss. With the improvement of tinnitus, the depressive state of patients can be alleviated accordingly.-
Key words:
- hearing loss, sensorineural /
- cochlear implantation /
- tinnitus /
- depression
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表 1 CI手术前后患者耳鸣等级、评分及抑郁评分情况
时间 THI-C等级 THI-C评分 BDI-Ⅱ-C评分 1级 2级 3级 4级 术前(n=166) 8 62 85 21 63.5±16.5 26.5±7.0 术后(n=166) 115 29 15 7 35.6±11.3 10.6±3.5 Z/t值 -9.478 69.128 58.531 P值 < 0.001 < 0.001 < 0.001 
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