Study on the relationship between benign paroxysmal positional vertigo and sleep disturbance
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摘要: 目的 通过对主客观睡眠情况的分析, 探讨良性阵发性位置性眩晕(BPPV)与睡眠障碍之间的关系。方法 选取符合纳入标准及排除标准的BPPV患者45例、对照组50例, 分别进行匹兹堡睡眠质量指数量表(PSQI)问卷调查及PSG监测, 并采用SPSS 23.0对结果进行对比分析。结果 相比对照组, BPPV患者的睡眠结构改变、AHI高、主观睡眠质量明显下降(P < 0.05), 且BPPV患者在治疗前后的PQSI分数也存在明显差异(P < 0.05)。对BPPV和AHI进行二元Logistic回归分析后发现, AHI指数每升高1, 患BPPV的概率将增加1.8倍(OR=2.80, 95%CI=2.25~3.66)。将AHI分组后再行回归分析发现, AHI≥5的患者患BPPV的风险是AHI < 5患者的3.94倍(OR=3.94, 95%CI=1.63~9.48)。结论 BPPV患者睡眠质量下降, 睡眠结构改变, AHI可能是BPPV发病的一项危险指标。Abstract: Objective To explore the relationship between benign paroxysmal positional vertigo (BPPV) and sleep disorders through the analysis of subjective and objective sleep conditions.Methods Forty-five patients with BPPV and fifty controls who met the inclusion and exclusion criteria were selected for Pittsburgh sleep quality index (PSQI) questionnaire survey and polysomnography (PSG) check, and SPSS 23.0 was used to compare and analyze the results.Results Compared with the control group, patients with BPPV had changes in sleep structure, high apnea hypopnea index (AHI) and significantly decreased subjective sleep quality (P < 0.05), and there were significant differences in the PQSI scores of patients with BPPV before and after treatment (P < 0.05).Binary logistic regression analysis of BPPV and AHI showed that for every 1 increase in AHI index, the probability of BPPV increased by 1.8 times (OR=2.80, 95%CI=2.25-3.66).After grouping AHI and performing regression analysis, it was found that the risk of BPPV in patients with AHI≥5 was 3.94 times that of patients with AHI < 5(OR=3.94, 95%CI=1.63-9.48).Conclusion Patients with BPPV have decreased sleep quality and altered sleep structure, and in this study, AHI is found to be a risk indicator for BPPV.
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Key words:
- vertigo /
- sleep disorders /
- sleep quality index scale /
- polysomnography
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表 1 BPPV组和对照组AHI构成比及回归分析
例(%) 组别 AHI < 5 AHI≥5 OR(95%CI) χ2 BPPV组 11(24.0) 34(76.0) 3.94(1.63~9.48) 9.75 对照组 28(55.0) 22(45.0) 
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