红细胞分布宽度在阻塞性睡眠呼吸暂停低通气综合征患者病情评估中的价值及其意义

刘宁; 李浩; 刘火旺; 王忠巧; 郑艳

doi:10.13201/j.issn.1001-1781.2019.06.018

红细胞分布宽度在阻塞性睡眠呼吸暂停低通气综合征患者病情评估中的价值及其意义

- 1 新疆医科大学第二附属医院耳鼻咽喉科(乌鲁木齐, 830063);
- 2 新疆医科大学第五附属医院耳鼻咽喉科;
- 3 中南大学湘雅三医院耳鼻咽喉头颈外科
基金项目:
国家自然科学基金 (No:81460095)

详细信息

通讯作者: 郑艳,E-mail:zy91900@sina.com

中图分类号: R563.8

收稿日期: 2018-11-03

The value of red blood cell distribution width in the evaluation of patients with obstructive sleep apnea hypopnea syndrome

- 1 Department of Otorhinolaryngology, the Second Affiliated Hospital of Xinjiang Medical University, Urumqi, 830063, China;
- 2 Department of Otorhinolaryngology, the Fifth Affiliated Hospital of Xinjiang Medical University;
- 3 Department of Otorhinolaryngology Head and Neck Surgery, the Third Xiangya Hospital, Central South University

More Information

Corresponding author: ZHENG Yan, E-mail: zy91900@sina.com

Received Date: 03 November 2018

摘要

摘要: 目的:探讨红细胞分布宽度(RDW)与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者病情严重程度的相关性及其意义。方法:选取经PSG监测明确诊断的OSAHS住院患者112例为OSAHS组,以及年龄、性别、BMI相匹配的61名健康体检者为对照组。采集所有研究对象清晨空腹外周静脉血,并获得RDW、白细胞计数、红细胞计数、血红蛋白、红细胞平均体积、血小板计数等相关血液学指标。结果:OSAHS组RDW水平明显高于对照组,RDW值随着OSAHS的病情严重程度而逐渐升高,并与AHI呈正相关(r=0.259),与平均SaO₂(r=－0.279)、最低SaO₂(r=－0.328)、睡眠时间(r=－0.204)呈负相关,与BMI呈正相关(r=0.203)。结论:RDW值升高水平可能是OSAHS病情严重程度的指标。由于RDW通常包含在全血细胞计数中,因此可以提供一种经济实用的指标来初步评估OSAHS患者的病情,并优先考虑行睡眠呼吸监测。
- 睡眠呼吸暂停低通气综合征 /
- 阻塞性 /
- 红细胞分布宽度 /
- 病情评估
Abstract: Objective: To investigate the relationship between red blood cell distribution width (RDW) and severity of obstructive sleep apnea hypopnea syndrome (OSAHS). Method: A total of 112 patients with OSAHS who were diagnosed by PSG monitoring were selected as OSAHS group, and 61 healthy subjects with matched age, gender and BMI were selected as the control group. The peripheral venous blood of all subjects was collected in the morning, and relevant hematological indexes such as RDW, white blood cell count, red blood cell count, hemoglobin, mean red blood cell volume, and platelet count were obtained. Result: The RDW level in the OSAHS group was significantly higher than that in the control group. The RDW value increased gradually with the severity of OSAHS and was positively correlated with AHI(r=0.259), the mean SaO₂ (r=-0.279), the lowest SaO₂(r=-0.328), BMI(r=0.203) and negatively correlated with sleep time(r=-0.204). Conclusion: The elevated level of RDW may be an indicator of the severity of OSAHS. Since RDW is usually included in the complete blood count, it can provide an economical and practical indicator to initially assess the condition of OSAHS patients and prioritize polysomnography monitoring.
- sleep apnea hypopnea syndrome /
- obstructive /
- red blood cell distribution width /
- disease assessment

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