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摘要: 目的:总结颈部坏死性筋膜炎的临床特点及处理,为该类疾病的诊治提供参考。方法:回顾性分析61例颈部坏死性筋膜炎患者的临床资料。61例患者均尽早行彻底手术清创,并积极予以广谱抗生素治疗。结果:14例出现并发症,2例死亡。59例最终治愈,随访至今(至少3个月)无复发或死亡,3例出现声嘶。结论:颈部坏死性筋膜炎发病后应尽早行彻底的手术清创并积极抗感染、控制合并疾病以及全身支持治疗。Abstract: Objective: To investigate the clinical characteristics and treatment of cervical necrotizing fasciitis. Method: Clinical data of 61 patients were analyzed retrospectively. All patients were underwent surgical debridement and treated with broad-spectrum antibiotics after diagnose. Result: Complications occurred in 14 patients. Fifty-nine patients were cured while 2 patients died. After 3 months or more follow-up, 3 patients accompanied with sequelae of vocal hoarseness, and no patient recurred or died. Conclusion: Early surgical debridement and the use of antibiotics should be taken as soon as possible after diagnosis of cervical necrotizing fasciitis, as well as control of comorbidities and systemic support treatment in order to prevent complications and deaths.
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Key words:
- necrotizing fasciitis /
- infection /
- debridement
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[1] GUNARATNE D A, TSEROS E A, HASAN Z, et al.Cervical necrotizing fasciitis:Systematic review and analysis of 1235 reported cases from the literature[J].Head Neck, 2018, 40:2094-2102.
[2] PAZ MAYA S, DUALDE BELTRÁN D, LEMERCIER P, et al.Necrotizing fasciitis:an urgent diagnosis[J].Skeletal Radiol, 2014, 43:577-589.
[3] SHAIKH N, UMMUNISSA F, HANSSEN Y, et al.Hospital epidemiology of emergent cervical necrotizing fasciitis[J].J Emerg Trauma Shock, 2010, 3:123-125.
[4] SANDNER A, MORITZ S, UNVERZAGT S, et al.Cervical necrotizing fasciitis-the value of the laboratory risk indicator for necrotizing fasciitis score as an indicative parameter[J].J Oral Maxillofac Surg, 2015, 73:2319-2333.
[5] LANISNIK B, CIZMAREVIC B.Necrotizing fasciitis of the head and neck:34 cases of a single institution experience[J].Eur Arch Otorhinolaryngol, 2010, 267:415-421.
[6] ELANDER J, NEKLUDOV M, LARSSON A, et al.Cervical necrotizing fasciitis:descriptive, retrospective analysis of 59 cases treated at a single center[J].Eur Arch Otorhinolaryngol, 2016, 273:4461-4467.
[7] GUIDERA A K, DAWES P J, FONG A, et al.Head and neck fascia and compartments:no space for spaces[J].Head Neck, 2014, 36:1058-1068.
[8] 赵雅铭, 易红良, 关建, 等.29例颈部坏死性筋膜炎临床分析[J].临床耳鼻咽喉头颈外科杂志, 2014, 28 (7):490-492.
[9] 洪艺云, 林功标, 林昶, 等.成人咽旁 (咽后) 间隙脓肿临床危险因素分析[J].临床耳鼻咽喉头颈外科杂志, 2018, 32 (17):1304-1308.
[10] SKITARELIC N, MLADINA R, MOROVIC M, et al.Cervical Necrotizing Fasciitis:Sources and outcomes[J].Infection, 2003, 31:39-44.
[11] HAKKARAINEN T W, KOPARI N M, PHAM T N, et al.Necrotizing soft tissue infections:review and current concepts in treatment, systems of care, and outcomes[J].Curr Probl Surg, 2014, 51:344-362.
[12] FIHMAN V, RASKINE L, PETITPAS F, et al.Cervical necrotizing fasciitis:8-years'experience of microbiology[J].Eur J Clin Microbiol Infect Dis, 2008, 27:691-695.
[13] KRENK L, NIELSEN H U, CHRISTENSEN M E.Necrotizing fasciitis in the head and neck region:an analysis of standard treatment effectiveness[J].Eur Arch Otorhinolaryngol, 2007, 264:917-922.
[14] DJUPESLAND P G.Necrotizing fascitis of the head and neck——report of three cases and review of the literature[J].Acta Otolaryngol Suppl, 2000, 543:186-189.
[15] MAO J C, CARRON M A, FOUNTAIN K R, et al.Craniocervical necrotizing fasciitis with and without thoracic extension:management strategies and outcome[J].Am J Otolaryngol, 2009, 30:17-23.
[16] WONG C H, WANG Y S.The diagnosis of necrotizing fasciitis[J].Curr Opin Infect Dis, 2005, 18:101-106.
[17] CAMINO JUNIOR R, NACLERIO-HOMEM M G, CABRAL L M, et al.Cervical necrotizing fasciitis of odontogenic origin in a diabetic patient complicated by substance abuse[J].Braz Dent, 2014, 25:69-72.
[18] 葛鑫颖, 刘良发, 路承, 等.食管异物穿孔致颈深间隙感染及纵隔脓肿的诊治[J].临床耳鼻咽喉头颈外科杂志, 2018, 32 (4):292-294.
[19] 丛铁川, 刘玉和, 高为华, 等.肺炎克雷伯杆菌颈部坏死性筋膜炎3例及文献复习[J].临床耳鼻咽喉头颈外科杂志, 2013, 27 (19):1080-1083.
[20] PANDA N K, SIMHADRI S, SRIDHARA S R.Cervicofacial necrotizing fasciitis:can we expect a favourable outcome[J]?J Laryngol Otol, 2004, 118:771-777.
[21] LUPPENS D, PIETTE C, RADERMECKER R P, et al.Depression and type 2 diabetes:etiopathogenic analysis of a frequent comorbidity[J].Rev Med Lieqe, 2014, 69:611-617.
[22] JALLALI N, WITHEY S, BUTLER P E.Hyperbaric oxygen as adjuvant therapy in the management of necrotizing fasciitis[J].Am J Surg, 2005, 189:462-466.
[23] FAUN∅ T J, PIKELIS A, OVESEN T.Hyperbaric oxygen may only be optional in head and neck necrotizing fasciitis:a retrospective analysis of 43 cases and review of the literature[J].Infect Dis (Lond), 2017, 49:792-798.
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