Clinical and pathologic analysis of 2 684 cases of papillary thyroid carcinoma in 8 years
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摘要: 目的:探讨甲状腺乳头状癌(PTC)患者的临床病理特征及年度特征。方法:回顾2010-2017年初次就诊于西安交通大学第一附属医院并行手术治疗的PTC患者的临床病理资料,描述分析其临床病理特征的年间变化。结果:8年间收集PTC患者共计2 684例,发病高峰年龄31~60岁,最高峰年龄41~55岁;男41~45岁,女46~50岁。8年间PTC患者的平均患病年龄差异无统计学意义(P>0.05)。总的男女比例在1.00:2.91波动(P>0.05)。男、女患者数量均呈上升趋势(P<0.05),增长近似平行。多灶性PTC及单灶性癌的比例近似平行(P>0.05)。PTC伴桥本甲状腺炎的比例呈现逐年上升趋势(P<0.05)。甲状腺微小乳头状癌中央区淋巴结转移率为15.81%,且其百分率8年间呈现逐年上升趋势(P<0.05)。结论:2010-2017年间PTC患者总数不断上升,平均患病年龄、性别比例差异无统计学意义,男、女患者数量增长近似平行。多灶性PTC及单灶性癌的比例近似平行。PTC伴桥本甲状腺炎的百分率呈逐年上升趋势,甲状腺微小乳头状癌的百分率呈现逐年上升趋势。Abstract: Objective: To study the clinicopathological and annual features of PTC patients in the past 8 years. Method: Review the clinicopathological data of PTC patients treated by surgery for the first time in the First Affiliated Hospital of Xi'an Jiaotong University from 2010 to 2017. Result: The total number of PTC patients was 2 684, which was increasing from 2010 to 2017. The peak age of onset of PTC was 31-60 years old, and the highest peak age was 41-55 years old, including 41-45 years for men and 46-50 years for women. There was no significant difference in the average age of PTC patients during the 8 years(P>0.05). The total male/female ratio oscillated between 1.00:2.91 and there was no significant difference(P>0.05). The increase in the number of male and female patients was approximately parallel. Both had an upward trend(P<0.05). The proportions of multifocal and single-tumor cancers were nearly parallel in the 8 years, and there was no significant difference(P>0.05). The percentage of PTC combined with HT increased year by year(P<0.05). The percentage of PTMC showed an increasing trend year by year(P<0.05). The rate of lymph node metastasis in the central area of PTMC was 15.81%.Conclusion: During the past 8 years, the growing number of PTC patients with different genders was approximately parallel. There was no significant difference in the average age and total male/female ratio of PTC patients. The proportions of multifocal and single-tumor cancers were nearly parallel. The percentage of PTC combined with HT has been increasing year by year. The percentage of PTMC showed an increasing trend.
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Key words:
- papillary thyroid carcinoma /
- clinical pathology
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