双调蛋白及其在气道炎性疾病中作用的研究进展

高玲; 许昱

doi:10.13201/j.issn.1001-1781.2018.01.016

双调蛋白及其在气道炎性疾病中作用的研究进展

高玲,
许昱^,

- 武汉大学人民医院耳鼻咽喉头颈外科(武汉, 430060)
基金项目:
国家自然科学基金面上项目（No：81770986，No：81371070）；湖北省自然科学基金项目（No：2015CKB756）

详细信息

通讯作者: 许昱,E-mail:xy37138@163.com

中图分类号: R764

收稿日期: 2017-11-10

Research progress of amphiregulin and its role in airway inflammatory disease

GAO Ling,
XU Yu^,

More Information

Corresponding author: XU Yu, E-mail: xy37138@163.com

Received Date: 10 November 2017

摘要

- 双调蛋白 /
- 气道炎性疾病
Abstract: Amphiregulin is a member of epidermal growth factor family, and is also one of the ligand of epidermal growth factor receptor, it participates in many physiological and pathological process by combining with EGFR. Researches have proved that AREG participates in asthma and airway inflammatory diseases caused by smoking and PM 2.5, and AREG plays an important role in the process of airway remodeling and inflammation. This paper mainly reviews the expression and function of AREG, and focus on it's research status in airway inflammatory disease.
- amphiregulin /
- epidermal growth factor receptor

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参考文献(37)

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