改良整体骨炎评分在慢性鼻-鼻窦炎中的临床应用

李云霞, 林枫, 成雷, 等. 改良整体骨炎评分在慢性鼻-鼻窦炎中的临床应用[J]. 临床耳鼻咽喉头颈外科杂志, 2017, 31(21): 1666-1670. doi: 10.13201/j.issn.1001-1781.2017.21.011
引用本文: 李云霞, 林枫, 成雷, 等. 改良整体骨炎评分在慢性鼻-鼻窦炎中的临床应用[J]. 临床耳鼻咽喉头颈外科杂志, 2017, 31(21): 1666-1670. doi: 10.13201/j.issn.1001-1781.2017.21.011
LI Yunxia, LIN Feng, CHENG Lei, et al. Clinical application of modified global osteitis score in chronic rhinosinusitis[J]. J Clin Otorhinolaryngol Head Neck Surg, 2017, 31(21): 1666-1670. doi: 10.13201/j.issn.1001-1781.2017.21.011
Citation: LI Yunxia, LIN Feng, CHENG Lei, et al. Clinical application of modified global osteitis score in chronic rhinosinusitis[J]. J Clin Otorhinolaryngol Head Neck Surg, 2017, 31(21): 1666-1670. doi: 10.13201/j.issn.1001-1781.2017.21.011

改良整体骨炎评分在慢性鼻-鼻窦炎中的临床应用

  • 基金项目:

    北京市医院管理局“登峰”人才培养计划 (No:DFL20150202)

    北京市教育委员会科技计划重点项目 (No:KZ201410025029)

    院内科研种子基金 (No:2016-YJJ-ZZL-017) 联合资助

详细信息
    通讯作者: 周兵, E-mail:entzhou@263.net
  • 中图分类号: R765.21

Clinical application of modified global osteitis score in chronic rhinosinusitis

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  • 目的: 探讨改良整体骨炎评分(GOSS)在慢性鼻-鼻窦炎中的临床应用价值。方法: 前瞻性研究,连续纳入药物治疗无效准备行鼻内镜手术的71例慢性鼻-鼻窦炎患者,通过OsiriX软件测量鼻窦CT,根据双侧额窦、筛窦、蝶窦、上颌窦骨炎的范围及厚度行GOSS评分及改良GOSS评分(同法,只测量双侧蝶窦及上颌窦),并于术前行视觉模拟量表(VAS)、鼻腔鼻窦结局测试-22(SNOT-22)、Lund-Kennedy(L-K)、Lund-Mackay(L-M)评分,术后1年进行疗效评判,再次行VAS、SNOT-22、L-K、L-M评分。应用SPSS 23.0软件分析改良GOSS评分的临床价值。结果: ①改良GOSS评分与GOSS之间存在显著线性正相关(r=0.913,P<0.001);②改良GOSS评分及GOSS评分与术前及术后L-K评分、L-M评分间存在相关性,改良GOSS评分与其相关性更高(r=0.316、0.357);与主观VAS评分、SNOT-22评分之间相关性差异无统计学意义(P>0.05);③检验不同评分者间GOSS评分与改良GOSS评分的差异,GOSS评分组内相关系数为0.933(95%CI 0.893~0.958),改良GOSS评分组内相关系数为0.947(95%CI 0.916~0.967),改良GOSS评分较GOSS评分其信度及一致性更好。结论: 改良GOSS评分能够更客观准确地反映慢性鼻-鼻窦炎患者骨炎程度,简化测量,信度及一致性良好,便于临床应用。
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收稿日期:  2017-06-15

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