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摘要: 目的: 探讨改良整体骨炎评分(GOSS)在慢性鼻-鼻窦炎中的临床应用价值。方法: 前瞻性研究,连续纳入药物治疗无效准备行鼻内镜手术的71例慢性鼻-鼻窦炎患者,通过OsiriX软件测量鼻窦CT,根据双侧额窦、筛窦、蝶窦、上颌窦骨炎的范围及厚度行GOSS评分及改良GOSS评分(同法,只测量双侧蝶窦及上颌窦),并于术前行视觉模拟量表(VAS)、鼻腔鼻窦结局测试-22(SNOT-22)、Lund-Kennedy(L-K)、Lund-Mackay(L-M)评分,术后1年进行疗效评判,再次行VAS、SNOT-22、L-K、L-M评分。应用SPSS 23.0软件分析改良GOSS评分的临床价值。结果: ①改良GOSS评分与GOSS之间存在显著线性正相关(r=0.913,P<0.001);②改良GOSS评分及GOSS评分与术前及术后L-K评分、L-M评分间存在相关性,改良GOSS评分与其相关性更高(r=0.316、0.357);与主观VAS评分、SNOT-22评分之间相关性差异无统计学意义(P>0.05);③检验不同评分者间GOSS评分与改良GOSS评分的差异,GOSS评分组内相关系数为0.933(95%CI 0.893~0.958),改良GOSS评分组内相关系数为0.947(95%CI 0.916~0.967),改良GOSS评分较GOSS评分其信度及一致性更好。结论: 改良GOSS评分能够更客观准确地反映慢性鼻-鼻窦炎患者骨炎程度,简化测量,信度及一致性良好,便于临床应用。Abstract: Objective: To compare GOSS and a newly proposed modified scoring system for assessment of CRS with osteitis.Method: Seventy-one CRS patients were enrolled prospectively. Their preoperative computed tomography (CT) were assessed for severity and extent of osteitis by two otolaryngologists using OsiriX DICOM Viewer software. The method of measurement was similar with GOSS, which retained scoring maxillary and sphenoid, producing a modified global osteitis score(rang:0-20). Collected the history and completed VAS, SNOT-22, Lund-Kennedy, Lund-Mackay in preoperative. Postoperative follow-up mounted up to 12 months and evaluating CRS patients' outcome. Compared for test-retest and inter-rater reliability between the modified system and GOSS.Result: There is a significant linear positive correlation between Modified GOSS score and GOSS (r=0.913, P<0.001). And Modified GOSS had more association with pre and postoperative L-M and L-K scores than GOSS (r=0.316, 0.357). The modified GOSS showed the highest inter-rater and test-retest, interclass correlation coefficient (pre-ICC=0.947; post-ICC=0.943).Conclusion: Modified GOSS may be a more suitable and convenient scoring system for clinical practice to grading osteitis.
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Key words:
- chronic rhinosinusitis /
- osteitis /
- modified global osteitis score /
- outcomes
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[1] BACHERT C, PAWANKAR R, ZHANG L, et al.ICON:chronic rhinosinusitis[J].World Allergy Organ J, 2014, 7:25-31.
[2] BHANDARKAR N D, SAUTTER N B, KENNEDY D W, et al.Osteitis in chronic rhinosinusitis:a review of the literature[J].Int Forum Allergy Rhinol, 2013, 3:355-363.
[3] BOLGER W E, LEONARD D, DICK E J Jr, et al.Gram negative sinusitis:a bacteriologic and histologic study in rabbits[J].Am J Rhinol, 1997, 11:15-25.
[4] PERLOFF J R, GANNON F H, BOLGER W E, et al.Bone involvement in sinusitis:an apparent pathway for the spread of disease[J].Laryngoscope, 2000, 110:2095-2099.
[5] KHALID A N, HUNT J, PERLOFF J R, et al.The role of bone in chronic rhinosinusitis[J].Laryngoscope, 2002, 112:1951-1957.
[6] SNIDVONGS K, EARLS P, DALGORF D, et al.Osteitis is a misnomer:a histopathology study in primary chronic rhinosinusitis[J].Int Forum Allergy Rhinol, 2014, 4:390-396.
[7] 韩德民, 周兵, 刘华超, 等.鼻内窥镜鼻窦手术几项与疗效有关因素的探讨[J].中华耳鼻咽喉头颈外科杂志, 1996, 31 (1):12-15.
[8] KENNEDY D W, SENIOR B A, GANNON F H, et al.Histology and histomorphometry of ethmoid bone in chronic rhinosinusitis[J].Laryngoscope, 1998, 108:502-507.
[9] BIEDLINGMAIER J F, WHELAN P, ZOARSKI G, et al.Histopathology and CT analysis of partially resected middle turbinates[J].Laryngoscope, 1996, 106:102-104.
[10] WESTRIN K M, NORLANDER T, STIERNA P, et al.Experimental maxillary sinusitis induced by Bacteroides fragilis:a bacteriological and histological study in rabbits[J].Acta Otolaryngol, 1992, 112:107-114.
[11] GEORGALAS C, VIDELER W, FRELING N, et al.Global Osteitis Scoring Scale and chronic rhinosinusitis:a marker of revision surgery[J].Clin Otolaryngol, 2010, 35:455-461.
[12] SNIDVONGS K, MCLACHLAN R, SACKS R, et al.Correlation of the Kennedy Osteitis Score to clinico-histologic features of chronic rhinosinusitis[J].Int Forum Allergy Rhinol, 2013, 3:369-375.
[13] 董怿, 周兵, 牛延涛, 等.兔鼻窦炎模型骨质重塑CT评估[J].中华耳鼻咽喉头颈外科杂志, 2010, 46 (10):848-853.
[14] 董怿, 周兵, 牛延涛, 等.兔鼻窦炎模型骨质重塑组织学观察及CT评估[J].中国耳鼻咽喉头颈外科, 2011, 18 (10):548-553.
[15] 成雷, 黄振校, 周兵, 等.整体骨炎评分系统在慢性鼻-鼻窦炎中的临床应用及骨炎评估的意义[J].中华耳鼻咽喉头颈外科杂志, 2013, 48 (2):119-122.
[16] 成雷, 黄振校, 周兵, 等.影响慢性鼻-鼻窦炎骨炎的相关因素临床分析[J].中华耳鼻咽喉头颈外科杂志, 2014, 49 (3):205-209.
[17] 林枫, 周兵, 成雷, 等.整体骨炎评分与慢性鼻-鼻窦炎预后的相关性分析[J].中国耳鼻咽喉颅底外科杂志, 2015, 21 (1):8-13.
[18] KIM H Y, DHONG H J, LEE H J, et al.Hyperostosis may affect prognosis after primary endoscopic sinus surgery for chronic rhinosinusitis[J].Otolaryngol Head Neck Surg, 2006, 135:94-113.
[19] BHANDARKAR N D, MACE J C, SMITH T L.The impact of osteitis on disease severity measures and quality of life outcomes in chronic rhinosinusitis[J].Int Forum Allergy Rhinol, 2011, 1:372-380.
[20] TELMESANI L M, AL-SHAWARBY M.Osteitis in chronic rhinosinusitis with nasal polyps:a comparative study between primary and recurrent cases[J].Eur Arch Otorhinolaryngol, 2010, 267:721-724.
[21] FOKKENS W J, LUND V J, MULLOL J, et al.European Position Paper on Rhinosinusitis and Nasal Polyps 2012[J].Rhinol Suppl, 2012, 3:1-298.
[22] 中华医学会耳鼻咽喉头颈外科学分会, 中华耳鼻咽喉科杂志编辑委员会.慢性鼻-鼻窦炎诊断和治疗指南 (2012年, 昆明)[J].中华耳鼻咽喉头颈外科杂志, 2013, 48 (2):92-94.
[23] VIDELER W J, GEORGALAS C, MENGER D J, et al.Osteitic bone in recalcitrant chronic rhinosinusitis[J].Rhinology, 2011, 49:139-147.
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