变应性鼻炎患病率及危险因素Meta分析

胡思洁; 魏萍; 寇巍; 武小芳; 刘萌雅; 陈成; 姚红兵

doi:10.13201/j.issn.1001-1781.2017.19.006

变应性鼻炎患病率及危险因素Meta分析

- 重庆医科大学附属儿童医院耳鼻咽喉头颈外科(重庆, 400014)
基金项目:
重庆市社会事业与民生保障科技创新专项 (No:cstc2015shmszx120022)

国家自然科学基金青年基金项目 (No:81600781)

重庆医科大学科研培育基金项目 (No:201405)

重庆市渝中区科技计划项目 (No:20150118)

详细信息

通讯作者: 姚红兵, E-mail:yaohongbing@163.net

中图分类号: R765.21

收稿日期: 2017-07-16

Prevalence and risk factors of allergic rhinitis:a Meta-analysis

- Department of Otorhinolaryngology Head and Neck Surgery, Children's Hospital of Chongqing Medical University, Chongqing, 400014, China

More Information

Corresponding author: YAO Hongbing, E-mail: yaohongbing@163.net

Received Date: 16 July 2017

摘要

摘要: 目的: 通过Meta分析,了解中国变应性鼻炎(AR)的患病率及探讨国内人群AR的主要危险因素,为AR的防治提供科学依据。方法: 系统检索Pubmed、Embase、Web of science、Cochrane图书馆、中国期刊全文数据库、中文科技期刊全文数据库、万方数字化期刊全文数据库、中国生物医学文献数据库等数据库查找关于中国AR患病率及危险因素相关文献,同时追索纳入文献的参考文献。采用R3.2.3软件对各研究结果进行Meta分析。结果: 共纳入31篇文献,国内儿童AR患病率为15.79%(95%CI 15.13~16.45),华中地区患病率最高(17.20%),华东最低(13.94%)。成人AR患病率为13.26%(95%CI 12.05~14.47),华南地区患病率最高(15.45%),西南最低(10.93%)。各危险因素合并比值比(OR)分别为家族史(5.40)、粉尘接触史(2.04)、药物过敏史(2.83)、哮喘病史(4.45)、环境烟草烟雾(2.00)、水泛滥(1.50)、装修(1.41)、花粉过敏(17.18)、真菌(1.31)、饲养宠物(1.29)、蟑螂(1.69)。结论: 中国AR的流行趋势研究发现,国内儿童AR患病率高于成人,不同地区患病率有差异,上述11种危险因素在AR的发病中起重要作用,在AR的防治过程中应针对这些危险因素进行早期干预。
- 鼻炎 /
- 变应性 /
- 患病率 /
- 危险因素 /
- Meta分析
Abstract: Objective: To clarify the morbidity and risk factors of allergic rhinitis (AR) in China so as to provide scientific basis for prevention of AR in the relevant populations.Method: Pubmed, Embase, Web of science, Cochrane Library, CNKI, VIP, Wanfang Data, CBM databases were searched for associated studies. The prevalence and risk factors of AR in China were retrieved from individual studies and the pooled estimates generated by R3.2.3 software.Result: Thirty-one cross-sectional studies were included in the Meta-analysis. The results indicated that the incidences of AR in Chinese children were 15.79% (95%CI 15.13-16.45). The highest prevalence is 17.20% in central China, the lowest is 13.94% in eastern China. The incidences of AR in Chinese adult were 13.26% (95%CI 12.05-14.47). The highest prevalence is 15.45% in southern China, the lowest is 10.93% in southwestern China. The pooled odds ratio (OR) values of family history (5.40), dust exposure history (2.04), drug allergy history (2.83), history of asthma (4.45), environmental tobacco smoking (ETS) (2.00), water damage (1.50), upholstering (1.41), pollen allergy (17.18), molds (1.31), keeping pets (1.29), cockroach (1.69).Conclusion: A study on the epidemic tendency of AR in China showed the morbidity of AR in Chinese children is higher than adult. Moreover, prevalence vary from region to region. Eleven kinds of risk factors mentioned above play imperative roles in the pathogenesis of AR. The early interventions which are associated with risk factors should be implemented in AR.
- rhinitis /
- allergic /
- prevalence /
- risk factors /
- Meta-analysis

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