胃蛋白酶检测在咽喉反流疾病诊断中的应用

王秀; 陈伟; 王秋萍

doi:10.13201/j.issn.1001-1781.2017.09.023

胃蛋白酶检测在咽喉反流疾病诊断中的应用

- 南京总医院耳鼻咽喉-头颈外科(南京, 210000)

详细信息

通讯作者: 王秋萍,E-mail:qpwang1016@vip.sina.com

中图分类号: R276.1

收稿日期: 2017-02-19

The clinical significance of pepsin in the diagnosis of laryngopharyngeal reflux disease

More Information

Corresponding author: WANG Qiuping, E-mail: qpwang1016@vip.sina.com

Received Date: 19 February 2017

摘要

- 咽喉反流疾病 /
- 胃蛋白酶
Abstract: Laryngopharyngeal reflux diseases(LPRD)refers to a kind of clinical syndrome that is caused by the [H⁺] and pepsin in the stomach entering the pharynx,larynx,nose,the middle ear,trachea and bronchi through esophagus.This disease has been gradually recognized by otolaryngologist in recent years.Upper respiratory tract infections caused by LPRD are often misdiagnosed or underdiagnosed,because its clinical symptoms and signs are usually nonspecific.Correct diagnosis of LPRD is the key to giving patients proper treatment.With the deepening of LPRD research,otolaryngologists gradually recognize that pepsin plays an important role in the cure of laryngopharynx trauma caused by reflux.Detection of upper and lower airway secretion of pepsin may be a promising diagnostic method for LPRD with high sensitivity.
- laryngopharyngeal reflux diseases /
- pepsin

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