Abstract: Objective: To study the relative factors of endoscopic surgical effect in chronic rhinosinusitis.Method: The study included 179 chronic rhinosinusitis patients in our hospital who had a nasal endoscopic surgery from January 2013 to June 2014, and evaluate the treatment effect one year after the surgery,the patients were divided into two groups:recurrent and non-recurrent. Collecting clinical data and using uni-variate and multivariate analysis to find out the risk factors of recurrence, then the regression equation was established.Result: There are 29 cases of recurrence and 150 cases of non-recurrent in the total 179 chronic rhinosinusitis patients with a nasal endoscopic surgery.Uni-variate analysis showed that smoking,nasal polyps, allergic rhinitis,bronchial asthma,deviation of nasal septum, gastro-esophageal reflux disease,scores of VAS,maxillary sinus integral,anterior ethmoid sinus integral,posterior ethmoid sinus integral,sphenoid sinus integral,frontal sinus integral,ostiomeatal complex integral,total sinus integral were statistically significant between chronic rhinosinusitis recurrent group and non-recurrent group(P<0.05). Multivariate analysis showed that smoking,nasal polyps, allergic rhinitis, bronchial asthma, deviation of nasal septum,scores of VAS,anterior ethmoid sinus integral,sphenoid sinus integral, ostiomeatal complex integral, total sinus integral were statistically significant between chronic rhinosinusitis recurrent group and non-recurrent group(P<0.05). Among those factors, smoking,nasal polyps, allergic rhinitis,scores of VAS,anterior ethmoid sinus integral,sphenoid sinus integral are the strongest in difference.Conclusion: The effect of chronic rhinosinusitis endoscopic surgery is not only related to clinical typing,but also closely related to smoking,nasal polyps, allergic rhinitis and their severity.