The significance of prophylactic migraine therapy in controlling familial Meniere's disease, a preliminary study
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摘要: 目的：探讨控制偏头痛能否改善家族性梅尼埃病患者的眩晕发作。方法：将16例家族性梅尼埃病患者分为不伴偏头痛组与偏头痛组。对偏头痛组患者给予预防性控制偏头痛干预，与不伴偏头痛组对照观察眩晕控制情况。结果：不伴偏头痛组给予梅尼埃病治疗后，眩晕控制有效率明显高于偏头痛组。而偏头痛组患者在加用预防性偏头痛治疗后，眩晕发作明显控制，控制水平与不伴偏头痛组相当。结论：联合偏头痛治疗对伴偏头痛的梅尼埃病患者的眩晕发作有良好的控制效果。Abstract: Objective: To investigate the effect of prophylactic migraine therapy in controlling vertigo episode of Meniere's disease.Method: We prospectively collected 16 cases of familial Meniere' disease diagnosed in our vertigo outpatient. The patients were divide into without migraine group(WOM) and with migraine group(WM). Give WM group a prophylactic therapy for migraine and compare within groups about the follow-up results of vertigo episodes.Result: WOM group had better results in controlling vertigo, then the controlling effect equaled after we added a prophylactic therapy for migraine.Conclusion: Combined with prophylactic migraine therapy may have better effect in accompanying migraine patients when controlling familial Meniere's disease.
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Key words:
- Meniere disease /
- migraine disorders /
- vertigo
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[1] MORRISON A W,BAILEY M E,MORRISON GA.Familial Ménière's disease:clinical and genetic aspects[J].J Laryngol Otol,2009,123:29-37.
[2] 高云,单希征,王秋菊.梅尼埃病的病因及发病机制研究进展[J].听力学及言语疾病杂志,2014,22(4):18-23.
[3] 中华耳鼻咽喉头颈外科杂志编辑委员会,中华医学会耳鼻咽喉科学分会.梅尼埃病的诊断依据和疗效评估(2006年,贵阳)[J].中华耳鼻咽喉头颈外科杂志,2007,42(3):163-163.
[4] WIPPERMAN J.Dizziness and vertigo[J].Prim Care,2014,41:115-131.
[5] RADTKE A,LEMPERT T,GRESTY M A,et al.Migraine and Ménière's disease:is there a link[J]?Neurology,2002,59:1700-1704.
[6] PARKER W.Menière's disease.Etiologic considerations[J].Arch Otolaryngol Head Neck Surg,1995,121:377-382.
[7] RASSEKH C,HARKER L A.The prevalence of migraine in Meniere's disease[J].Laryngoscope,1992,102:135-138.
[8] REQUENA T,ESPINOSA-SANCHEZ J M,CA-BRERA S,et al.Familial clustering and genetic heterogeneity in Meniere's disease[J].Clin Genet,2014,85:245-252.
[9] 中华医学会疼痛学分会,头面痛学组.中国偏头痛诊断治疗指南(2011年)[J].中国疼痛医学杂志,2011,17(2):65-86.
[10] LOPEZ-ESCAMEZ J A,DLUGAICZYK J,JACOBSJ,et al.Accompanying Symptoms Overlap during Attacks in Menière's Disease and Vestibular Migraine[J].Front Neurol,2014,5:265-265.
[11] MORRISON A W,JOHNSON K J.Genetics(molecular biology)and Meniere's disease[J].Otolaryngol Clin North Am,2002,35:497-516.
[12] CHA Y H,KANE M J,BALOH R W.Familial clustering of migraine,episodic vertigo,and Ménière's disease[J].Otol Neurotol,2008,29:93-96.
[13] HIETIKKO E,KOTIMÄKI J,KENTALA E,et al.Finnish familial Meniere disease is not linked to chromosome 12p12.3,and anticipation and cosegregation with migraine are not common findings[J].Genet Med,2011,13:415-420.
[14] FRYKHOLM C,LARSEN H C,DAHL N,et al.Familial Ménière's disease in five generations[J].Otol Neurotol,2006,27:681-686.
[15] CHA Y H,BRODSKY J,ISHIYAMA G,et al.The relevance of migraine in patients with Meńière's disease[J].Acta Otolaryngol,2007,127:1241-1245.
[16] LEE J M,KIM M J,JUNG J,et al.Genetic aspects and clinical characteristics of familial Meniere's disease in a South Korean population[J].Laryngoscope,2015,125:2175-2180.
[17] LEE H,LOPEZ I,ISHIYAMA A,et al.Can migraine damage the inner ear[J]?Arch Neurol,2000,57:1631-1634.
[18] GHAVAMI Y,MAHBOUBI H,YAU A Y,et al.Migraine features in patients with Meniere's disease[J].Laryngoscope,2016,126:163-168.
[19] GATES P.Hypothesis:could Meniere's disease be a channelopathy[J]?Intern Med J,2005,35:488-489.
[20] CHA Y H,BALOH R W.Migraine associated vertigo[J].J Clin Neurol,2007,3:121-126.
[21] SEEMUNGAL B,KASKI D,LOPEZ-ESCAMEZ JA.Early Diagnosis and Management of Acute Vertigo from Vestibular Migraine and Ménière's Disease[J].Neurol Clin,2015,33:619-628.
[22] TEGGI R,GATTI O,SYKOPETRITES V,et al.Association of cinnarizine and betahistine in prophylactic therapy for Ménière's disease with and without migraine[J].Acta Otorhinolaryngol Ital,2014,34:349-353.
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