Hypofibrinogenemia caused by hemocoagulase after endoscopic sinus surgery:a case report
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Abstract: A 61year-old male patient,plasma fibrinogen level was 2.98g/L,endoscopic sinus surgery was performed under general anesthesia for polypoid of uncinate process with mycotic maxillary sinusitis.Hemocoagulase were given in pre-and post-operative for treatment.The patient was found postoperative drain blood continuously since 3days after surgery,when the dose of hemocoagulase reach 26 KU,and fibrinogen determined in Plasma was 0.48g/L.Coagulation returned to normal and nasal bleeding stopped after discontinuation of the hemocoagulase and supplement with fibrinogen.
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Key words:
- hemocoagulase /
- fibrinogen /
- haemorrhage
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[1] 袁琳,邹小蓉,陈艳梅.注射用白眉蛇毒血凝酶的临床应用调查分析[J].药物流行病学杂志,2015,24(2):122-124.
[2] 吴广通,张夏华,石玉岚.注射用白眉蛇毒血凝酶止血机制初步研究[J].中国药物导报,2011,8(1):47-49.
[3] 黄俊何.白眉蝮蛇毒血凝酶的药理作用和临床应用[J].蛇志,2010,22(1):39-41.
[4] 许航宇,舒海荣.白眉蛇毒血凝酶在内镜鼻窦手术中的止血效果[J].中国生化药物杂志,2011,32(1):54-56.
[5] 蔡晓菁,严喆,张家雄.白眉蛇毒血凝酶在鼻内镜手术中的作用[J].同济大学学报(医学版),2014,35(1):118-119,123-123.
[6] 王兆,李建琴,曹丽娟.长期使用蛇毒血凝酶致低纤维蛋白原血症三例报告及文献复习[J].中华血液学杂志,2014,35(1):50-52.
[7] 孟景晔,骆子文,朱惠敏.蛇毒血凝酶引起低纤维蛋白血症6例[J].中国输血杂志,2014,27(4):446-447.
[8] KOLLMAN J M,PANDI L,SAWAYA M R,et al.Crystal structure of human fibrinogen[J].Biochemistry,2009,48:3877-3886.
[9] 王永先,包斌,宋瑞瑞,等.纤维蛋白原的空间结构特征[J].生物科学进展,2012,43(5):397-401.
[10] PING L,HUANG L,CARDINALI B,et al.Substitution of the humanαC region with the analogous chicken domain generates a fibrinogen with severely impaired lateral aggregation:fibrin monomers assemble into protofibrils but protofibrils do not assemble into fibers[J].Biochemistry,2011,50:9066-9075.
[11] 蒋品,肖春洁.凝血项中纤维蛋白原与凝血酶时间检测结果相关性分析[J].实用医技杂志,2008,15(2):189-190.
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