Analysis of allergens characteristic in 1172 patients with allergic rhinitis in Changzhou area
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摘要: 目的:分析收集的常州地区2008-2015年的变应性鼻炎(AR)患者的变应原谱分布情况。方法:已诊断为AR的1 172例患者用德国敏筛变应原检测系统检测血清中变应原特异性IgE抗体(sIgE),分析各种变应原的阳性率,以及在患者年龄、性别、季节等方面的差异。结果:常州地区变应原阳性率最高的前几位变应原是户尘螨、混合真菌、屋尘、牛奶、狗毛皮屑、矮豚草、栎榆梧桐等混合花粉、猫毛皮屑。变应原在不同年龄AR患者中的分布差异有统计学意义(P<0.05),尘螨、真菌、屋尘、牛奶、狗毛皮屑、猫毛皮屑、鸡蛋白在未成年组中的阳性率高于成年组(P<0.05);矮豚草、栎榆梧桐等混合花粉、腰果、蟑螂、蟹则在成年组中的阳性率高于未成年组(P<0.05)。变应原在同年龄段内男女性之间的分布差异无统计学意义(P>0.05)。不同季节变应原阳性率之间比较差异有统计学意义(P<0.05)。结论:常州地区AR患者最常见的变应原是户尘螨、真菌和屋尘,不同年龄和季节的变应原分布有变化,可为临床诊断提供参考。Abstract: Objective:To determine the distribution of allergens in patients with allergic rhinitis during from 2008 to 2015 in Changzhou area.Method:Allergy Screen method was used to detect the specifical-allergen IgE levels of 1 172 patients with allergic rhinitis.Among the patients, the distribution of all allergens was analyzed.The positive rate was compared with age, gender, season and so on.Result:The most common allergens in allergic rhinitis patients in Changzhou were dust mite, fungus, house dust, milk, dander of dog, weed mixture, farina and dander of cat. The more higher positive rates of dust mite, fungus, house dust, milk, dander of dog, dander of cat, eggs were found in teenager group than adult group (P<0.05). There were more higer positive rates of weed mixture, farina, cashew, cockroaches and crab in teenager group than adult group(P<0.05). There was no significant difference of positive rate between female group and male group. There was significant difference of variation with seasons. Conclusion:Dust mite, fungus and house dust were the most common allergens among patiens with allergic rhinitis in Changzhou area. The positive rates of allergens varied with ages and seasons.
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Key words:
- rhinitis /
- allergic /
- specific IgE
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