外耳及中耳恶性肿瘤39例临床分析

辛颖; 严森; 宋为明; 潘滔; 谢华顺; 柯嘉; 李丽娟; 段清川; 宋昱; 马芙蓉

doi:10.13201/j.issn.1001-1781.2015.14.007

外耳及中耳恶性肿瘤39例临床分析

- 北京大学第三医院耳鼻咽喉科(北京, 100191)

详细信息

通讯作者: 马芙蓉,E-mail:furongma@126.com

中图分类号: R732.2

收稿日期: 2015-03-10

39 cases of malignant tumors originated from external and middle ear

- Department of Otolaryngology, Peking University Third Hospital, Beijing, 100191, China

More Information

Corresponding author: MA Furong, E-mail: furongma@126.com

Received Date: 10 March 2015

摘要

摘要: 目的:对1994-2011年间我科收治的39例外耳及中耳恶性肿瘤患者的临床表现、治疗方法及预后进行回顾分析。方法:39例耳部恶性肿瘤中,男23例,女16例;平均年龄59岁。
- ear neoplasms /
- diagnosis /
- treatment
Abstract: Objective: To describe our experience in the clinical manifestation and treatment of malignant tumors of the external and middle ear.Method: The study reviewed 39 patients between 1994-2011 in our hospital, including 15 pinna tumors, 18 external canal tumors and 6 middle ear tumors. 23 males and 16 females were enrolled in this study. The mean age of patients at the time of surgery was 59. Radiotherapy or radiotherapy and chemotherapy were the only possible treatment in 6 cases. Thirty-three patients were treated surgically, and 9 patients also received radiotherapy after surgery.Result: All of the patients had been followed up over 3 years, except for 1 case of external canal and 1 case of middle ear tumor. The 3-year survival of pinna, external canal and middle ear tumors were 86.7%, 82.4% and 60.0% respectively. At the last follow up, the pinna tumors showed that the survival rate was 100% in T₁, T₂ and Tx stage, and 0% in T₄ stage; the external canal tumors showed that the survival rate was 90% in T₁ stage, and 66.7% in T₂, T₃ stage; the middle ear tumors showed that the survival rate was 100% in T₁ and T₂ stage, 0% in T₃ stage.Conclusion: The T staging system is for an important prognostic factor, and it is important for an early diagnosis and radical surgery to achieve a better therapeutical result.
- ear neoplasms /
- diagnosis /
- treatment

HTML全文

参考文献(11)

[1]	RODRIGUEZ P A, GIL C R, ARENAS B O,et al.[Malignant tumours of the external auditory canal and of the middle ear] [J]. Acta Otorrinolaringol Esp,2004. 55:470-474.
[2]	AHMAD I, DAS G A R. Epidemiology of basal cell carcinoma and squamous cell carcinoma of the pinna[J].J Laryngol Otol,2001,115:85-86.
[3]	STELL P M, MCCORMICK M S. Carcinoma of the external auditory meatus and middle ear. Prognostic factors and a suggested staging system[J].J Laryngol Otol,1985,99:847-850.
[4]	NEMECHEK A J, AMEDEE R G. Tumors of the external ear[J].J La State Med Soc,1995,147:239-242.
[5]	CHANG C H, SHU M T, LEE J C,et al. Treatments and outcomes of malignant tumors of external auditory canal[J].Am J Otolaryngol,2009,30:44-48.
[6]	LIU S C, KANG B H, NIEH S,et al. Adenoid cystic carcinoma of the external auditory canal[J].J Chin Med Assoc,2012,75:296-300.
[7]	MORTON R P, STELL P M, DERRICK P P. Epidemiology of cancer of the middle ear cleft[J].Cancer,1984,53:1612-1617.
[8]	邱明月,王以仁. 中耳恶性肿瘤115例分析[J].浙江医学,1984,5(1):11-12.
[9]	田双莲. 55例外耳道及中耳癌的临床及疗效分析[J].肿瘤研究与临床,2003,4(4):272-273.
[10]	LEONG S C, YOUSSEF A, LESSER T H. Squamous cell carcinoma of the temporal bone:outcomes of radical surgery and postoperative radiotherapy[J].Laryngoscope,2013,123:2442-2448.
[11]	BACCIU A, CLEMENTE I A, PICCIRILLO E, et al. Guidelines for treating temporal bone carcinoma based on long-term outcomes[J].Otol Neurotol,2013,34:898-907.