眼肌前庭诱发肌源性电位在良性阵发性位置性眩晕病变定位诊断中的应用

鲁保才; 余文发; 吴志燕; 连荣; 卢振民; 杨建斌

doi:10.13201/j.issn.1001-1781.2015.14.006

眼肌前庭诱发肌源性电位在良性阵发性位置性眩晕病变定位诊断中的应用

- 1 新乡医学院第一附属医院耳鼻咽喉科(河南卫辉, 453100);
- 2 新乡医学院第一附属医院口腔科
基金项目:
河南省高等学校青年骨干教师资助计划(No:2010GGJS-120)

河南省卫生科技创新人才工程(No:2010141)

详细信息

通讯作者: 杨建斌,E-mail:yangjb7683@163.com

中图分类号: R441.2

收稿日期: 2015-05-01

The diagnosis applying effects of ocular vestibular evoked myogenic potentials in BBPV disease

- 1 Department of Otolaryngology, the First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, China;
- 2 Department of Seamatology the First Affiliated Hospital of Xinxiang Medical University

More Information

Corresponding author: YANG Jianbin, E-mail: yangjb7683@163.com

Received Date: 01 May 2015

摘要

摘要: 目的:探讨眼肌前庭诱发肌源性电位(oVEMP)在良性阵发性位置性眩晕(BPPV)病变定位诊断中的应用效果。方法:选择2012-09-2015-01期间在我院体检中心的健康体检者80例作为对照组,同期选择原发性BPPV患者80例作为观察组,2组都进行全功能听觉诱发电位分析,测定oVEMP与颈肌前庭诱发肌源性电位(cVEMP)的异常情况、波幅、阈值、P1潜伏期、N1潜伏期等。结果:观察组中的cVEMP异常率为28.8%,oVEMP异常率为38.8%,而对照组的cVEMP与oVEMP异常率分别为1.3%和2.5%,组间对比差异有统计学意义(P<0.05)。观察组的oVEMP测试振幅为(5.98±2.15)μv,N1潜伏期为(10.03±0.76)ms,而对照组分别为(4.09±2.11)μv、(11.67±0.78)ms,对比差异有统计学意义(P<0.05)。观察组的cVEMP测试振幅(154.8±43.92)μv,而对照组为(180.49±45.34)μv,对比差异有统计学意义(P<0.05)。结论:BPPV患者的oVEMP异常,其对椭圆囊功能损害程度超过球囊,可对受试者的耳石器功能进行客观的评判,有利于疾病判定。
Abstract: Objective: To investigate the diagnosis applying effects of ocular vestibular evoked myogenic potentials(oVEMP) in peripheral BPPV disease.Method: During September 2012 to January 2015, we selected 80 healthy people in our hospital medical center as the control group, choose the same period of primary benign paroxysmal positional vertigo as the observation group of 80 patients. Two groups were carried out fully functional auditory evoked potential analysis, determination of oVEMP and cervical vestibular evoked myogenic potentials (cVEMP) anomaly amplitude threshold, P1 latencies, N1 incubation period.Result: The cVEMP abnormal rate in the observation group was 28.8%, the oVEMP abnormal rate was 38.8%, while cVEMP and oVEMP abnormal rates in the control group was 1.3% and 2.5% respectively that compared to significant differences between the two groups(P<0.05). The oVEMP test amplitude in the observation group was (5.98±2.15)μv, the N1 incubation period was (10.03±0.76)ms, while the control group were (4.09±2.11)μv and (11.67±0.78) ms that compared difference were statistically significant (P<0.05). The cVEMP test amplitude in the observation group was (154.8±43.9)2 μv, while the control group was (180.49±45.34)μv, compared the difference was statistically significant (P<0.05). Conclusion: Paroxysmal positional vertigo patients ocular vestibular evoked myogenic potentials abnormal rate is relatively high, the utricle dysfunction for more severe than the balloon can be the subject of an objective function of the ear stone judgment, judgment in favor of the disease.

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