不同镇痛方式在悬雍垂腭咽成形术后镇痛的疗效比较

张立坤; 邵东风; 谷彬; 梁振; 李海春; 王东海

doi:10.13201/j.issn.1001-1781.2015.11.009

不同镇痛方式在悬雍垂腭咽成形术后镇痛的疗效比较

- 1. 唐山市协和医院耳鼻咽喉头颈外科(河北唐山, 063000);
- 2. 开滦总医院重症医学科

详细信息

通讯作者: 王东海,E-mail:WDHai988@sina.com

中图分类号: R767.91

收稿日期: 2015-03-10

Comparison of the effects of different analgesic methods after UPPP

- 1. Department of Otolaryngology Head and Neck Surgery, Union Hospital of Tangshan, Tangshan, 063000, China;
- 2. Kailuan General Hospital, Intensive Care Unit

More Information

Corresponding author: WANG Donghai, E-mail: WDHai988@sina.com

Received Date: 10 March 2015

摘要

摘要: 目的:探讨不同镇痛方式在悬雍垂腭咽成形术后镇痛疗效的比较。方法:90例悬雍垂腭咽成形术患者,随机分为空白对照组、帕瑞昔布钠组、曲马多组,每组30例。空白对照组对患者不应用任何镇痛措施;帕瑞昔布钠组是在术后给予患者肌内注射帕瑞昔布钠40 mg,术后12、24、36 h再分别肌内注射40 mg;曲马多组在患者术后12、24、36 h分别肌内注射100 mg曲马多。3组患者于术后12、24、36、48、72、96 h进行VAS评分,观察其嗜睡、恶心、呕吐、头晕、皮疹等不良反应。结果:采取镇痛措施的帕瑞昔布钠组和曲马多组较空白对照组疼痛均有减轻;帕瑞昔布钠组较曲马多组疼痛评分明显下降,差异有统计学意义(P<0.05)。结论:帕瑞昔布钠应用于悬雍垂腭咽成形术后镇痛效果明显,较曲马多效果好,副作用少,值得临床推广。
- 帕瑞昔布钠 /
- 悬雍垂腭咽成形术 /
- 镇痛 /
- 曲马多
Abstract: Objective:To explore the effects of different analgesia methods after UPPP.Method:Ninety cases of patients uvulopalatopharyngoplasty were divided into 3 groups randomly, and 30 cases in each group. The group A was the blank control group without any analgesia measures. The cases in group B were treated with intramuscular injection of parecoxib sodium 40 mg after surgery immediately, and continued injecting 40 mg after 12 hours, 24 hours and 36 hours respectively.100 mg tramadol replaced 40 mg parecoxib sodium in group C. The VAS scoring was performed after surgery 12, 24, 36, 48, 72, 96 hours in 3 groups, and we observed adverse reaction such as lethargy, nausea, vomiting, dizziness, skin rash and so on.Result:The group B and C reduced the pain significantly compared with blank control group. The pain scores in group B were significantly decreased than that in group C (P<0.05).Conclusion:The analgesic effect of parecoxib sodium after UPPP is significant and better than tramadol. It is worthy to use widely in clinical due to its better effect and less side effect.
- parecoxib sodium /
- uvulopalatopharyngoplasty analgesia /
- tramadol /

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