-
摘要: 目的:探讨健康青年人群气导短纯音诱发的眼肌前庭诱发肌源性电位(oVEMP)的特征性参数,并进行参数分析及正常值的计算。方法:55例健康青年人作为受试者,均采用500 Hz气导短纯音单侧给声对侧记录。记录55例(110耳)的P1-N1复合波引出阈值,P1和N1的潜伏期,P1-N1波间期及P1-N1复合波振幅,以获得临床正常值范围,同时分析性别对oVEMP各参数的影响。结果:55例(110耳)均引出典型的P1-N1复合波,引出率为100%。oVEMP的引出阈值(正常听力级nHL)为(82.23±2.92)dBHL;95 dBHL气导短纯音刺激下获得P1的潜伏期(11.53±0.80)ms;N1的潜伏期(16.61±0.87)ms,P1-N1波间期(5.18±1.04)ms,P1-N1复合波振幅(5.96±2.59)μV。31例男性受试者P1-N1复合波振幅为(6.49±2.67)μV,24例女性为(5.28±2.34)μV,二者比较差异有统计学意义(P<0.05)。结论:气导短纯音诱发的oVEMP是一种新兴的前庭功能检测方法,在oVEMP的P1-N1复合波振幅上存在性别差异,应按照性别分别建立oVEMP的正常值范围。
-
关键词:
- 眼肌前庭诱发肌源性电位 /
- 阈值 /
- 潜伏期
Abstract: Objective: To investigate the characteristics of air-conducted ocular vestibular-evoked myogenic potential (oVEMP) in healthy young people , so as to establish the normative data of young people. Method: Fifty-five healthy young subjects were recruited as study participants, 500 Hz air-conducted tone burst was used as stimulation.The threshold of oVEMP in each ear was examined. The latencies of P1 and N1,P1-N1 interval,peak-to-peak of P1-N1 amplitude and asymmetry ratio were measured.Effects of gender on oVEMPs were also examined. Result: The typical complex wave of N1 and P1 was observed in all subjects.The threshold of oVEMP examination was(82.23±2.92) dBHL,95 dBHL air-conducted get the latencies of P1and N1,P1-N1 interval,peak-to-peak P1-N1 amplitude in these healthy young people were(11.53±0.80)ms,(16.61±0.87)ms,(5.18±1.04)ms,(5.96±2.59)μv,respectively. The peak-to-peak P1-N1 amplitude of male was (6.49±2.67) μv,the female was (5.28±2.34) μv, there were significant differences between male and female subjects in the wave amplitude (P<0.05). Conclusion: Air-conduction induced oVEMP is a new method for vestibular function test. The amplitude of the oVEMP wave was different between male and female. Therefore it is necessary to establish the normal value according to genders.-
Key words:
- ocular vestibular evoked myogenic potential /
- threshold /
- latency
-
[1] ROSENGREN S M,WELGAMPOLA M S,COLEBATCH J G. Vestibular evoked myogenic potentials:past.present and future[J]. Clin Neurophysiol,2010,121:636-651.
[2] CURTHOYS I S. A critical review of the neurophysiological evidence underlying clinical vestibular testing using sound, vibration and galvanic stimuli[J].Clin Neurophysiol,2010,12:132-144.
[3] NGUYEN K D,WELGAMPOLA M S,CAREY J P. Test-retest reliability and age-related characteristics of the ocular and cervical evoked myogenic potential tests[J]. Otol Neurotol,2010,31:793-802.
[4] MUROFUSHI T,WAKAYAMA K,CHIHARA Y.oVEMP to air-conducted tones reflects functions of different vestibular populations from cVEMP[J]? Eur Arch Otorhinolaryngol,2010,267:995-996.
[5] HONG S M,YEO S G,BYUN J Y,et al.Subjective visual veical during eccentric rotation in patients with vestibular neuritis[J].Eur Arch Otorhinolaryngol,2010,267:357-361.
[6] VALKO Y,HEGEMANN S C,WEBER K P,et al.Relative diagnostic value of ocular vestibular evoked potentials and the subjective visual vertical during tilt and eccentric rotation[J].Clin Neurophysiol,2011,122:398-404.
[7] MURNANE O D, AKIN F W, KELLY K J, et al. Effects of stimulus and recording parameters on the air conduction ocular vestibular evoked myogenic potential[J].J Am Acad Audiol,2011,22:469-480.
[8] WANG S J, JAW F S, YOUNG Y H. Ocular vestibular-evoked myogenic potentials elicited from monaural versus binaural acoustic stimulations[J].Clin Neurophysiol,2009,120:420-423.
[9] ZHANG A S, GOVENDER S, COLEBATCH J G. Tuning of the ocular vestibular evoked myogenic potential to bone-conducted sound stimulation [J]. J Appl Physiol(1985),2012,112:1279-1290.
[10] HSU Y S,WANG S J,YOUNG Y H.Ocular vestibular-evoked myogenic potentials in children using air conducted sound stimulation[J]. Clin Neurophysiol,2009,120:1381-1385.
[11] 张青,宋辉,胡娟,等. 气导短纯音诱发的眼肌前庭诱发肌源性电位在健康青年人群中的波形特征[J]. 中华耳鼻咽喉头颈外科杂志,2012,47(1):15-18.
[12] SUNG P H, CHENG P W, YOUNG Y H. Effect of gender on ocular vestibular-evoked myogenic potentials via various stimulation modes[J]. Clin Neurophysiol,2011,122:183-187.
[13] 谢溯江,贾宏博,毕红哲,等. 健康飞行员与飞行学员气导声诱发的在眼外肌上记录的前庭诱发肌源性电位[J]. 中华耳科学杂志,2011,9(1):4-7.
计量
- 文章访问数: 57
- PDF下载数: 12
- 施引文献: 0