复发性喉癌的外科挽救治疗

徐夏; 李湘平; 刘雄; 田文栋

doi:10.13201/j.issn.1001-1781.2014.07.013

复发性喉癌的外科挽救治疗

- 广州市南方医院耳鼻咽喉头颈外科(广州, 510515)

详细信息

通讯作者: 李湘平

中图分类号: R739.65

收稿日期: 2013-09-14

Salvage surgery for recurrent laryngocarcinoma

- Department of Otolaryngology Head and Neck Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China

More Information

Corresponding author: LI Xiangping

Received Date: 14 September 2013

摘要

摘要: 目的:探讨喉癌复发患者采用手术治疗的疗效及预后。方法:采用挽救性手术治疗43例复发喉癌患者。采用Kaplan-Meier法计算生存率,Log-rank检验单因素分析临床因素对预后的影响。结果:挽救术后并发症为23.3%(10/43),其中感染及咽瘘发生率18.6%(8/43)。挽救手术后随访满3年有32例患者,3年生存率为56.3%,满5年有25例患者,5年生存率为32.0%,首诊分期与3年生存率相关(P<0.05)。喉内复发组及喉功能保留组预后较好,但差异无统计学意义。结论:挽救性手术是复发性喉癌较好的治疗方法,其预后与首诊分期相关,对局部复发的喉癌患者选择性保留喉功能可获得较好的疗效及预后。
- 喉肿瘤 /
- 复发 /
- 挽救疗法 /
- 预后
Abstract: Objective:To study the curative effect and prognosis of salvage surgery performed for recurrent laryngocarcinoma.Method:The clinical data of 43 patients with salvage surgery for recurrent laryngocarcinoma hospitalized in Nanfang Hospital between 2003 and 2011 were analyzed retrospectively. Survival analysis was performed by using Kaplan-Meier method and prognosis factors were analyzed by Log-rank test.Result:After salvage surgery, 10 (23.3%) patients developed postoperative complications. Pharyngocutaneous fistula and infection occurred in 8 (18.6%) patients. Kaplan-Meier analysis showed that patients survived for 3-year (n=32) and 5-year (n=25) after salvage surgery were 56.3% and 32.0% respectively. Univariate analysis indicated that clinical stage in the first diagnosis was significantly correlated with 3 year overall survival (P<0.05). Local recurrence of laryngeal cavity group and preservation of laryngeal function group had a good prognosis respectively, but no significant difference between them. Conclusion:Salvage surgery is a good choice for recurrent laryngeal carcinoma. Outcomes of these patients were correlated with clinical stages. Laryngeal function preserving surgery for local recurrent laryngeal carcinoma can achieve a expected curative effect and prognosis.
- laryngeai neoplasms /
- recurrence /
- salvage surgery /
- prognosis

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参考文献(10)

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