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摘要: 目的:探讨颈段食管癌的外科治疗方法及保留喉功能手术治疗的意义及可行性。方法:回顾性分析手术治疗颈段食管癌患者16例的临床资料,手术方式中,喉及喉咽全部切除食管内翻拔脱管状胃代食管术12例;喉及喉咽全部切除+颈段食管切除气管代食管术1例;部分下咽+颈段食管切除喉气管瓣代食管术1例;保留喉的食管内翻拔脱管状胃代食管术2例。均同期行双侧颈廓清术。结果:无手术死亡,手术切除率100%。术后并发肺部感染2例,吻合口瘘2例,吻合口狭窄2例,心功能衰竭1例,失访3例。喉功能保留率12.5%。3年生存率30.7%,5年生存率23.1%。结论:颈段食管癌可行非开胸食管内翻拔脱术切除肿瘤,以管状胃、喉气管瓣修复食管缺损,根据肿瘤所在部位及侵及范围,尽可能保留喉功能。Abstract: Objective: To investigate the method of surgical management for cervical esophageal carcinoma and the feasibility of the operation with preservation of laryngeal function.Method: Sixteen patients with cervical esophageal carcinoma who received surgical treatment were reviewed in our retrospective study. Removal of total hypopharynx and larynx and the inversion stripping esophagectomy were conducted in thirteen patients,of which one underwent the reconstraction with residual larynx and tracheal flap and the other twelve patients underwent the reconstraction with gastric-pharyngeal anastomosis. One patient received the cervical esophagectomy and partial hypopharyngectomy with laryngotracheal flap.The inversion stripping esophagectomy with laryngeal function preservation were conducted in two patients,who received the reconstraction with gastric-pharyngeal anastomosis and preserved total laryngx. All the patients were carried out the bilateral neck dissections.Result: The surgical resection rate was 100% and no operative death occured. The postoperative complications included pulmonary infection in two cases,anastomotic fistula in two cases,anastomotic stenosis in two cases and congestive heart failure in one case.The retained rate of the larygeal function is 12.5%. The 3-year survival rate is 30.7%, and the 5-year survival rate is 23.1%.Conclusion: The surgical treatment of cervical esophageal carcinoma is possible.The inversion stripping esophagectomy without thoracotomy is performed to resect the tumor.The esophageal defect could be reconstracted by laryngotracheal flap or gastric-pharyngeal anastomosis.The laryngeal function should be remained as far as possible according to the location and extension of the tumor.
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[1] KELLEY D J, WOLF R, SHAHA A R,et al. Impact of clinicopathologic parameters on patient survival in carcinoma of the cervical esophagus[J]. Am J Surg,1995,170:427-431.
[2] 李树玲.新编头颈肿瘤学[M].北京:科学技术文献出版社,2002:810-824.
[3] COOPER J S, GUO M D, HERSKOVIC A,et al. Chemoradiotherapy of locally advanced esophageal cancer:long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group[J].JAMA,1999,281:1623-1627.
[4] WANG S, LIAO Z, CHEN Y, et al. Esophageal cancer located at the neck and upper thorax treated with concurrent chemoradiation:a single-institution experience[J]. J Thorac Oncol,2006,1:252-259.
[5] 屠规益,唐平章,祁永发,等.头颈外科处理颈段食管癌的经验[J].中华肿瘤杂志,1995,17(2):118-121.
[6] TIMON C V, TONER M, CONLON B J. Paratracheal lymph node involvement in advanced cancer of the larynx, hypopharynx, and cervical esophagus[J]. Laryngoscope,2003,13:1595-1599.
[7] HARTLEY B E, BOTTRILL D, HOWARD D J. A third decade's experience with the gastric pull-up operation for hypopharyngeal carcinoma:changeing patterns of use[J]. Laryngol Otol,1999,113:241-243.
[8] TONG D K, LAW S, KWONG D L, et al. Current management of cervical esophageal cancer[J]. World J Surg,2011,35:600-607.
[9] 王朝晖,陈锦,朱江,等.胃管状成形术在晚期下咽及颈段食管癌手术中的应用[J].中华耳鼻咽喉头颈外科杂志,2010,45(3):246-248.
[10] PUTTAWIBUL P, PORNPATANARAK C, SANGTHONG B,et al. Results of gastric pull-up reconstruction for pharyngolaryngo-oesophagectomy in advanced head and neck cancer and cervical oesophageal squamous cell carcinoma[J]. Asian J Surg,2004,27:180-185.
[11] 李佳,王铭辉,张华,等.不开胸食管剥脱术在颈段食管癌中的治疗价值[J].岭南现代临床外科,2007,7(5):370-372.
[12] 曾多,蒋俭,李建业,等.颈段食管癌的外科治疗[J].中国耳鼻咽喉头颈外科,2009,16(9):476-478.
[13] 徐成钧,李忠实,李树春,等.胸大肌岛状皮瓣在下咽及颈段食管癌术后重建中的应用[J].实用肿瘤学杂志,2002,16(2):138-139.
[14] 刘穹,王嘉陵,刘良发,等.自体游离空肠重建喉咽及颈段食管[J].中国耳鼻咽喉头颈外科,2008,15(11):605-607.
[15] 李志华,吴晨元,陶泽璋,等.喉气管瓣修复下咽颈部食管癌术后缺损[J].中国肿瘤临床,1997,24(5):355-357.
[16] 林心强,王挥戈,张燕,等.颈段食管癌手术喉功能保留问题的探讨[J].临床耳鼻咽喉头颈外科杂志,2007,21(20):935-941.
[17] 屠规益.喉癌下咽癌现代理论与临床[M].山东:山东科学技术出版社,2002:434-442.
[18] 王耀建,朱肇峰,陈伟雄,等.下咽颈段食管癌手术切除后保留喉功能与发声重建[J].临床耳鼻咽喉科杂志,2003,17(3):135-137.
[19] 杜晓东,栾信庸,雷大鹏,等.保留喉功能的非开胸食管拔脱颈段食管癌切除术[J].中华肿瘤杂志,2004,26(3):181-183.
[20] 张彬,唐平章,徐震纲,等.下咽环周缺损重建方法的选择[J].中华耳鼻咽喉科杂志,2004,39(7):419-424.
[21] 谢晋,董频,李克勇,等.颈段食管重建术中喉返神经的保护[J].中国耳鼻咽喉颅底外科杂志,2006,12(5):343-345.
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