锻炼咽腔与颏舌肌治疗阻塞性睡眠呼吸暂停低通气综合征

唐世雄, 王耀文, 卿菁, 等. 锻炼咽腔与颏舌肌治疗阻塞性睡眠呼吸暂停低通气综合征[J]. 临床耳鼻咽喉头颈外科杂志, 2013, 27(15): 822-826. doi: 10.13201/j.issn.1001-1781.2013.15.012
引用本文: 唐世雄, 王耀文, 卿菁, 等. 锻炼咽腔与颏舌肌治疗阻塞性睡眠呼吸暂停低通气综合征[J]. 临床耳鼻咽喉头颈外科杂志, 2013, 27(15): 822-826. doi: 10.13201/j.issn.1001-1781.2013.15.012
TANG Shixiong, WANG Yaowen, QING Jing, et al. Exercise pharynx and genioglossus to treat obstructive sleep apnea and hypopnea syndrome[J]. J Clin Otorhinolaryngol Head Neck Surg, 2013, 27(15): 822-826. doi: 10.13201/j.issn.1001-1781.2013.15.012
Citation: TANG Shixiong, WANG Yaowen, QING Jing, et al. Exercise pharynx and genioglossus to treat obstructive sleep apnea and hypopnea syndrome[J]. J Clin Otorhinolaryngol Head Neck Surg, 2013, 27(15): 822-826. doi: 10.13201/j.issn.1001-1781.2013.15.012

锻炼咽腔与颏舌肌治疗阻塞性睡眠呼吸暂停低通气综合征

  • 基金项目:

    宁波市科技计划社会发展项目(No:2010C50031)

详细信息
    通讯作者: 唐世雄,E-mail:nbtsx@yahoo.com.cn
  • 中图分类号: R766

Exercise pharynx and genioglossus to treat obstructive sleep apnea and hypopnea syndrome

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  • 目的:探讨锻炼咽腔与颏舌肌治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的方法及主客观疗效。方法:54例OSAHS患者(锻炼组)自选咽腔与颏舌肌锻炼法治疗,治疗前行Epworth嗜睡评分、PSG监测和320排CT检查上气道,记录其AHI、LSaO2、BMI,腭后区和舌后区的最小矢径和最小横径,计算各壁的顺应性。治疗6个月及12个月后再次行Epworth嗜睡评分、PSG监测与320排CT检查;并与同期悬雍垂腭咽成形术30例(对照1组)、21例因故未做任何治疗者(对照2组)进行比较。采用单因素方差分析比较三者主客观疗效及上气道顺应性变化。结果:锻炼6个月和12个月后复查PSG和320排CT,按2009年OSAHS指南有效率分别为31.48%和44.44%,其中轻中度者6个月有效率为44.74%,12个月有效率为63.16%;Epworth嗜睡评分由平均7.67分降至3.54分和3.25分,AHI由锻炼前平均22.84次/h下降至15.45次/h和13.60次/h(P<0.05),LSaO2由平均74.05%改善至81.18%和81.93%(P<0.01),锻炼前后主客观疗效显著(P<0.05)。对照1组6个月有效率为66.67%,明显高于锻炼组(P<0.05),但12个月有效率为36.67%,与锻炼组比较差异无统计学意义(P>0.05);锻炼组与对照2组比较差异有统计学意义(P<0.01)。320排CT测量各平面咽壁顺应性提示:锻炼12个月后腭后区前后壁顺应性较锻炼前下降(P<0.01),其余各壁顺应性无明显变化。锻炼前后BMI无明显变化(P>0.05)。结论:锻炼咽腔与颏舌肌治疗部分OSAHS患者能改善其症状,无创,无需治疗成本,尤其适用于老年患者和不适宜手术或不愿手术也不愿进行正压通气治疗的轻中度患者,也可作为其他针对OSAHS治疗的补充方法。
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收稿日期:  2012-11-29

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