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摘要: 目的: 探讨累及蝶窦的多发性骨髓瘤(MM)的临床特征、诊断及治疗,提高其临床诊治水平。方法: 回顾性分析2例累及蝶窦的MM患者的临床资料并复习文献。结果: 复视、头痛为累及蝶窦的MM患者的共同症状,同时还伴有全身其他器官受累的表现,患者有多次求医的经历。通过鼻内镜下蝶窦活检,经病理检查明确诊断为MM,患者行化疗后症状明显好转或得到控制。年龄较小的患者病情进展迅速,并发症多,预后差。结论: MM临床表现复杂,对于有蝶窦内病变、伴全身症状且病情进展较快者,应尽快行蝶窦活检,作出鉴别诊断,为患者赢得治疗时机。Abstract: Objective: To study the clinical characteristics, diagnosis and management of multiple myeloma involving sphenoid sinus.Method: The clinical data of 2 patients with multiple myeloma involving sphenoid sinus were reported and the relevant literatures were also reviewed.Result: Diplopia and headache were the common symptoms of the patients, and there were also some symptoms related to other organs. Patients often had repeated medical treatments and were finally diagnosed by the biopsy of sphenoid sinus. The disease progressed rapidly in the young patient.Conclusion: Characteristics of multiple myeloma are complicated. Biopsy of the sphenoid sinus is meaningful for patients with both sphenoid sinus tumor and systematic symptoms, especially those with rapid progress.
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Key words:
- multiple myeloma /
- plasmacytoma /
- sphenoid sinus
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[1] 陆再英,谢毅,钟南山,等.内科学[M].7版.北京:人民卫生出版社,2008:627-631.
[2] DORES G M,LANDGREN O,MCGLYNN K A,et al.Plasmacytoma of bone,extramedullary plasmacytoma,and multiple myeloma:incidence and survival in the U-nited States[J].Br J Haematol,2009,144:86-94.
[3] SHREIF J A,GOUMAS P D,MASTRONIKOLIS N,etal.Extramedullary plasmacytoma of the nasal cavity[J].Otolaryngol Head Neck Surg,2001,124:119-120.
[4] 黄宏明,吴佩娜,陈少华.头颈部髓外浆细胞瘤6例临床体会[J].实用医学杂志,2006,22(14):1653-1654.
[5] 谭志强,杨中纯,贺湘波,等.头颈部髓外浆细胞瘤14例报告并文献复习[J].中国耳鼻咽喉颅底外科杂志,2009,15(6):432-435.
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