江苏省常州地区变应性鼻炎患者变应原分析

姚聆清; 邱建鹤; 巢长江; 毛建军; 钱俊勇; 薛建荣; 周慧娟

doi:10.13201/j.issn.1001-1781.2012.23.007

江苏省常州地区变应性鼻炎患者变应原分析

- 1 江苏省常州市第一人民医院(苏州大学第三附属医院)耳鼻咽喉头颈外科(江苏常州, 213001);
- 2 江苏省常州市第三人民医院耳鼻咽喉科

详细信息

通讯作者: 邱建鹤,E-mail:mingyidf@hotmail.com

中图分类号: R765.21

收稿日期: 2011-11-28

Analysis on the allergens in allergic rhinitis patients in Changzhou district of Jiangsu

- 1 Department of Otorhinolaryngology Head and Neck Surgery, the Third Affiliated Hospital of Suzhou University, Changzhou, 213001, China;
- 2 Department of Otorhinolaryngology, the Third People's Hospital of Changzhou

More Information

Corresponding author: QIU Jianhe, E-mail: mingyidf@hotmail.com

Received Date: 28 November 2011

摘要

摘要: 目的:通过江苏省常州地区变应性鼻炎(AR)患者16种标准化变应原皮肤点刺试验的结果,汇总分析出本地区AR患者的主要变应原,为AR的合理防治及流行病学提供依据。方法:对4 242例临床疑似AR的患者进行皮肤点刺试验并进行结果分析。结果:点刺试验阳性者2 638例,阳性率为 62.19%;粉尘螨及户螨吸入性变应原阳性率分别以85.86%、83.55%列第1、2位,其次为蟑螂(11.49%)和葎草(9.82%),食入性变应原海虾(5.76%)列第5位,真菌(2.92%)排位靠后;各年龄段的主要变应原分布有差异;尘螨阳性等级为+++及++++的构成比在儿童组显著高于成人组(P＜0.01)。结论:本地区防治AR的重点应针对主要变应原尘螨。儿童与成人变应原亦有差异。
- 鼻炎,变应性 /
- 变应原 /
- 皮肤点刺试验
Abstract: Objective: To investigate the distribution of positive allergens in patients with allergic rhinitis in Changzhou.Method: A total of 4 242 cases with allergic symptoms and signs underwent skin prick test with 16 kinds of standardized allergens. The common allergens were found out. The samples were stratified on seven age groups to analysis the distributive characteristics of allergens responsible for each group. The samples were also stratified on children group and adults group to analysis their response degree to Dust mite.Result: 2 638 cases(62.19%) had the positive reaction, including male 1 380(52.3%) cases, female 1 258(47.7%) cases. Dermatophagoides farinae and Dermatophagodies pteronyssinus had the highest positive ratio(85.86%,83.55%) in inhalation group,followed cockroach(11.49%) and Humulus L.(9.82%), fungus(2.92%) in the lower positivie ratio.Shrimp(5.76%) was the most common allergen in food group. The distribution of common allergens in different age groups was variable. There was significantly higher sensitivity to dust mite between children group compared to adults group(P<0.01).Conclusion: The study shows that Dust mite was the mostly responsible common allergen in Changzhou district. The distribution of common allergens in children group and adults group was variable.
- rhinitis,allergic /
- allergen /
- skin prick test

HTML全文

参考文献(11)

[1]	王成硕,张罗,韩德民,等.北京地区变应性鼻炎患者吸入变应原谱分析[J].临床耳鼻咽喉科杂志,2006,20(5):204-207.
[2]	时文杰,张金梅,林鹏,等.天津地区676例变应性鼻炎患者变应原谱分析[J].临床耳鼻咽喉头颈外科杂志,2011,25(5):220-223.
[3]	符征,蔡飞,孙亮,等.海南省变应性鼻炎患者中变应原分布情况[J].中国耳鼻咽喉头颈外科,2007,14(1):17-18.
[4]	陈伟,陈始明,许昱,等.576例变态反应性鼻炎患者变应原点刺试验结果分析[J].中国医师进修杂志,2009,32(10):36-38.
[5]	张勇,李泽卿,江满杰,等.南京地区变应性鼻炎患者致敏原皮肤点刺试验结果分析及其临床意义[J].实用医学杂志,2008,24(22):3876-3878.
[6]	张玉君,朱华明,张维天,等.上海地区阿罗格皮肤点刺试验临床分析[J].上海交通大学学报(医学版),2007,27(9):1075-1077.
[7]	GENDO K,LARSON E B.Evidence-based diagnosticstrategies for evaluating suspected allergic rhinitis[J].Ann Intern Med,2004,140:278-289.
[8]	朱丽,马芙蓉,王丽,等.变应性鼻炎标准化变应原皮肤点刺试验[J].中国耳鼻咽喉头颈外科,2007,14(1):14-16.
[9]	吕云霞,谢志海,赵素萍,等.长沙地区变应性鼻炎患者的变应原分布特点及结果分析[J].临床耳鼻咽喉头颈外科杂志,2011,25(11):491-494.
[10]	黄学勤,荣光生,程学仕,等.皮肤点刺试验对变应性鼻炎变应原诊断的价值分析[J].中国中西医结合耳鼻咽喉科杂志,2009,17(3):154-155.
[11]	王泽海,林文森,李书彦,等.变应性鼻炎患病率及相关因素调查[J].中华耳鼻咽喉头颈外科杂志,2011,46(3):225-231.