Epworth嗜睡量表和微觉醒指数在重度OSAHS患者病情评估中的价值

陈曦; 章榕; 王洪洪; 李进让; 孙建军

doi:10.13201/j.issn.1001-1781.2017.03.001

Epworth嗜睡量表和微觉醒指数在重度OSAHS患者病情评估中的价值

- 海军总医院耳鼻咽喉头颈外科(北京, 100048)

详细信息

通讯作者: 陈曦,E-mail:xhcxyz@126.com

中图分类号: R563.8

收稿日期: 2016-11-08

The assessed value of Epworth sleep scale and arousal index in severe OSAHS patients

- Department of Otolaryngology Head and Neck Surgery, Navy General Hospital, Beijing, 100048, China

More Information

Corresponding author: CHEN Xi, E-mail: xhcxyz@126.com

Received Date: 08 November 2016

摘要

摘要: 目的:探讨Epworth嗜睡量表(ESS)和微觉醒指数在重度OSAHS患者病情评估中的价值。方法:经PSG确诊的1 193例重度OSAHS患者,按嗜睡程度分为3组,即轻度嗜睡组(ESS ≤ 12),中度嗜睡组(13 ≤ ESS ≤ 17),重度嗜睡组(ESS ≥ 18)。分别比较各组年龄、微觉醒指数(ArI)、AHI、AI、低通气指数(HI)、LSaO₂、BMI进行比较。对ESS、ArI与其他睡眠参数进行相关性分析。结果:3组ArI、AHI、AI、HI、LSaO₂差异均有统计学意义。ESS和ArI与AHI、AI呈弱正相关性(r=0.187~0.399, P<0.05),ESS和ArI与HI、LSaO₂呈弱负相关性(r=-0.14~-0.448, P<0.05)。结论:Epworth嗜睡量表和ArI在重度OSAHS患者病情评估中有重要价值。
- Epworth嗜睡量表 /
- 微觉醒指数 /
- 睡眠呼吸暂停低通气综合征 /
- 阻塞性
Abstract: Objective:The aim of this study was to study the assessed value of Epworth sleep scale(ESS) and arousal index in severe obstructive sleep apnea hypopnea syndrome(OSAHS)patients.Method: The 1193 severe OSAHS adults diagnosised by polysomnography recordings were divided into 3 groups according to ESS:the mild group(ESS ≤ 12), the moderate group(13 ≤ ESS ≤ 17) and the severe group(ESS ≥ 18). The apnea hypopnea index(AHI), apnea index (AI), hypopnea index(HI), the lowest oxygen saturation(LSaO₂), arousal index (ArI),and body mass index(BMI) were compared between each groups.Result:Significant differences were observed in ArI, AHI, AI, HI, LSaO₂ between each groups (P<0.05). ESS and ArI were positively correlated with AHI and AI(r=0.187-0.399, P<0.05).ESS and ArI showed a weak negative correlation with LSaO₂ and HI(r=-0.14——0.448, P<0.05).Conclusion:ArI and ESS are important indexes to evaluate the severity of severe OSAHS patients.
- Epworth sleep scale /
- arousal index /
- sleep apnea-hypopnea syndrome /
- obstructive

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参考文献(13)

[1]	中华耳鼻咽喉头颈外科杂志编辑委员会,中华医学会耳鼻咽喉头颈外科学分会咽喉学组.阻塞性睡眠呼吸暂停低通气综合征诊断和外科治疗指南[J].中华耳鼻咽喉头颈外科杂志,2009,44(2):95-96.
[2]	WICKWIRE E M,LETTIERI C J,CAIRNS A A,et al.Maximizing positive airway pressure adherence in adults:a common-sense approach[J].Chest,2013,144:680-693.
[3]	李进让,陈曦,孙建军.阻塞性睡眠呼吸暂停低通气综合征病情程度与高血压的关系[J].中华耳鼻咽喉头颈外科杂志,2012,47(2):97-100.
[4]	BERRY R B,GLEESON K.Respiratory arousal from sleep:mechanisms and significance[J].Sleep,1997,20:654-675.
[5]	JORDAN A S,ECKERT D J,WELLMAN A,et al.Termination of respiratory events with and without cortical arousal in obstructive sleep apnea[J].Am J Respir Crit Care Med,2011,184:1183-1191.
[6]	DYKEN M E,YAMADA T,GLENN C L,et al.Obstructive sleep apnea associated with cerebral hypoxemia and death[J].Neurology,2004,62:491-493.
[7]	RATNAVADIVEL R,CHAU N,STADLER D,et al.Marked reduction in obstructive sleep apnea severity in slow wave sleep[J].J Clin Sleep Med,2009,5:519-524.
[8]	CATCHESIDE P G,JORDAN A S.Reflex tachycardia with airway opening in obstructive sleep apnea[J].Sleep,2013,36:819-821.
[9]	NODA A,YASUMA F,OKADA T,et al.Influence of movement arousal on circadian rhythm of blood pressure in obstructive sleep apnea syndrome[J].J Hypertens,2000,18:539-544.
[10]	YUE H J,BARDWELL W,ANCOLI-ISRAEL S,et al.Arousal frequency is associated with increased fatigue in obstructive sleep apnea[J].Sleep Breath,2009,13:331-339.
[11]	ECKERT D J,YOUNES M K.Arousal from sleep:implications for obstructive sleep apnea pathogenesis and treatment[J].J Appl Physiol(1985),2014,116:302-313.
[12]	EDWARDS B A,ECKERT D J,MCSHARRY D G,et al.Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea[J].Am J Respir Crit Care Med,2014,190:1293-1300.
[13]	LOEWEN A,OSTROWSKI M,LAPRAIRIE J,et al.Determinants of ventilatory instability in obstructive sleep apnea:inherent or acquired[J]?Sleep,2009,32:1355-1365.