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Abstract: The patient, a 70-year-old woman, presented with a mass in the right nasal cavity accompanied by recurrent nosebleeds for 3 months. Physical examination revealed a mass in the right nasal vestibule, with a diameter of about 1.5 cm. The surface of the mass was not smooth and nasal CT showed a mass in the right nasal vestibule, which could be surgically removed. Immunohistochemical results of the tumor showed CKpan(3+), CK5/6(3+), p40(3+), p53(+), CD10(-), AR(-), Bcl-2(-), ki-67(+20%). Pathological diagnosis was acantholytic dyskeratotic acanthoma. This disease is rare and easy to be misdiagnosed, so it is necessary to pay attention to identification.
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Key words:
- nasal vestibule /
- acanthoma /
- immunohistochemistry
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[1] 丁瑜洁, 陈晓栋, 顾黎雄. 角化棘皮瘤和皮肤鳞状细胞癌凋亡相关蛋白表达的研究[J]. 中华皮肤科杂志, 2012, 45(2): 91-94. https://d.wanfangdata.com.cn/periodical/ChlQZXJpb2RpY2FsQ0hJTmV3UzIwMjExMTMwEg16aHBmMjAxMjAyMDA2Ggg3M2U1ZDh4aA%253D%253D
[2] 万川, 胡国红. 棘层松解角化不良性棘皮瘤[J]. 临床皮肤科杂志, 2012, 41(7): 413-415. doi: 10.3969/j.issn.1000-4963.2012.07.011
[3] Brownstein MH. Acantholytic acanthoma[J]. J Am Acad Dermatol, 1988, 19(5 Pt 1): 783-786.
[4] 兰雪梅, 谭欢, 杨希川, 等. 棘层松解性棘皮瘤1例[J]. 临床皮肤科杂志, 2014, 43(1): 35-36. https://www.cnki.com.cn/Article/CJFDTOTAL-LCPF201401021.htm
[5] Kaddu S, Dong H, Mayer G, et al. Warty dyskeratoma-"folliculardyskeratoma": analysis of clinicopathologic features of a distinctive follicular adnexal neoplasm[J]. J Am Acad Dermatol, 2002, 47(3): 423-428. doi: 10.1067/mjd.2002.122756
[6] 翟志芳, 阎衡, 杨希川, 等. 表皮松解性棘皮瘤[J]. 临床皮肤科杂志, 2010, 39(5): 299-300. doi: 10.3969/j.issn.1000-4963.2010.05.012
[7] 王白鹤, 宋昊, 陈浩, 等. 透明细胞棘皮瘤10例分析[J]. 中华皮肤科杂志, 2016, 49(10): 722-723. doi: 10.3760/cma.j.issn.0412-4030.2016.10.010
[8] 陈淑君, 骆肖群, 方栩. 面部角化棘皮瘤恶变为鳞癌1例[J]. 中国皮肤性病学杂志, 2004, 18(3): 174-175. doi: 10.3969/j.issn.1001-7089.2004.03.028
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