One case of recurrent giant cell tumor of the larynx and literature review
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摘要: 原发于喉部的巨细胞肿瘤极为罕见，本文介绍了1例术后复发的喉巨细胞肿瘤(giant cell tumor of the larynx，GCTL)患者。男，28岁，2022年6月因甲状腺肿块接受了甲状腺全切手术，术后病理诊断为软组织巨细胞肿瘤。2023年6月因颈部肿物复发再次入院，行部分喉部分下咽切除术，完整切除肿瘤。依据术后病理、免疫组织化学(H3.3 G34W+)和基因检测等辅助检查结果，颈部肿物最终诊断为GCTL。患者未进行放化疗，术后12个月复诊，未见肿瘤复发表现。Abstract: Giant cell tumors originating in the larynx are extremely rare. This article presents a case of a recurrent postoperative giant cell tumor of the larynx(GCTL). The patient, a 28-year-old male, underwent a total thyroidectomy in June 2022 due to a thyroid mass. The postoperative pathological diagnosis was giant cell tumor of soft tissues. The patient was readmitted in June 2023 due to the recurrence of the neck mass and underwent partial laryngectomy and partial hypopharyngectomy to completely remove the tumor. Based on postoperative pathology, immunohistochemistry(H3.3 G34W+), and genetic testing, the neck mass was ultimately diagnosed as GCTL. The patient did not receive radiotherapy or chemotherapy, and at the 12-month postoperative follow-up, there was no evidence of tumor recurrence.
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Key words:
- laryngeal carcinoma /
- giant cell tumor /
- recurrence
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