耳鼻喉科静脉血栓栓塞的流行病学及病因与预防的研究现状

贺璐; 龚树生

doi:10.13201/j.issn.2096-7993.2023.01.015

耳鼻喉科静脉血栓栓塞的流行病学及病因与预防的研究现状

贺璐¹,
龚树生^1, ,

- 首都医科大学附属北京友谊医院耳鼻咽喉头颈外科(北京，100050)

详细信息

通讯作者: 龚树生，E-mail：gongss1962@163.com

中图分类号: R364.1

收稿日期: 2022-04-07

刊出日期: 2023-01-03

The research status of epidemiology, etiology, and prevention measures of venous thromboembolism in ENT

HE Lu¹,
GONG Shusheng^1, ,

- Department of Otorhinolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China

More Information

Corresponding author: GONG Shusheng, E-mail: gongss1962@163.com

Received Date: 07 April 2022

Publish Date: 03 January 2023

摘要

摘要: 静脉血栓栓塞(VTE)是临床上最常见的可预防的围手术期患者死亡原因之一。VTE在耳鼻喉科发生风险较低，然而近年来随着耳鼻喉科的治疗范围不断拓展，复杂手术的开展逐渐增多，VTE的发生风险也随之增高。重新认识VTE在耳鼻喉科中的发生率、识别VTE的高危因素并进行早期预防对于降低VTE的发生率和围手术期患者死亡率具有重要意义。本文对耳鼻喉科VTE的流行病学、病因以及预防的研究现状作一综述，以期为耳鼻喉科VTE的临床诊治提供参考。
- 静脉血栓栓塞 /
- 流行病学 /
- 病因 /
- 预防
Abstract: Venous thromboembolism (VTE) is one of the most common preventable causes of death in perioperative patients. VTE has used to consider as low risk in ENT field. However, in recent years, the risk of VTE increases with expanding of the scope of ENT as well as the performing of complex surgeries. Re-understanding the incidence of VTE, identification of risk factors, and early prevention are important to reduce the morbidity and mortality of VTE in perioperative patients. This article reviewed the research status of epidemiology, etiology and prevention of VTE, with the aim of providing a reference for the clinical management of VTE in ENT department.
- venous thromboembolism /
- epidemiology /
- etiology /
- prevention

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参考文献(33)

[1]	Torbicki A, Perrier A, Konstantinides S, et al. Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology(ESC)[J]. Eur Heart J, 2008, 29(18): 2276-315. doi: 10.1093/eurheartj/ehn310
[2]	Zhan C, Miller MR. Excess length of stay, charges, and mortality attributable to medical injuries during hospitalization[J]. JAMA, 2003, 290(14): 1868-1874. doi: 10.1001/jama.290.14.1868
[3]	Zhai Z, Kan Q, Li W, et al. VTE Risk Profiles and Prophylaxis in Medical and Surgical Inpatients: The Identification of Chinese Hospitalized Patients' Risk Profile for Venous Thromboembolism(DissolVE-2)-A Cross-sectional Study[J]. Chest, 2019, 155(1): 114-122. doi: 10.1016/j.chest.2018.09.020
[4]	Gould MK, Garcia DA, Wren SM, et al. Prevention of VTE in nonorthopedic surgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines[J]. Chest, 2012, 141(2 Suppl): e227S-e277S.
[5]	Shuman AG, Hu HM, Pannucci CJ, et al. Stratifying the risk of venous thromboembolism in otolaryngology[J]. Otolaryngol Head Neck Surg, 2012, 146(5): 719-724. doi: 10.1177/0194599811434383
[6]	Moubayed SP, Eskander A, Mourad MW, et al. Systematic review and meta-analysis of venous thromboembolism in otolaryngology-head and neck surgery[J]. Head Neck, 2017, 39(6): 1249-1258. doi: 10.1002/hed.24758
[7]	Beswick DM, Vaezeafshar R, Ma Y, et al. Risk Stratification for Postoperative Venous Thromboembolism after Endoscopic Sinus Surgery[J]. Otolaryngol Head Neck Surg, 2018, 158(4): 767-773. doi: 10.1177/0194599818755340
[8]	Ahmad FI, Clayburgh DR. Venous thromboembolism in head and neck cancer surgery[J]. Cancers Head Neck, 2016, 1: 13. doi: 10.1186/s41199-016-0014-9
[9]	Mowery A, Light T, Clayburgh D. Venous thromboembolism incidence in head and neck surgery patients: Analysis of the Veterans Affairs Surgical Quality Improvement Program(VASQIP)database[J]. Oral Oncol, 2018, 77: 22-28. doi: 10.1016/j.oraloncology.2017.12.002
[10]	Cramer JD, Dilger AE, Schneider A, et al. Risk of Venous Thromboembolism Among Otolaryngology Patients vs General Surgery and Plastic Surgery Patients[J]. JAMA Otolaryngol Head Neck Surg, 2018, 144(1): 9-17.
[11]	Song Y, Alyono JC, Ali NE, et al. Postoperative Venous Thromboembolism after Extracranial Otologic Surgery[J]. Otolaryngol Head Neck Surg, 2019, 161(1): 144-149. doi: 10.1177/0194599819835743
[12]	Ali NE, Alyono JC, Song Y, et al. Postoperative Venous Thromboembolism after Neurotologic Surgery[J]. J Neurol Surg B Skull Base, 2021, 82(3): 378-382. doi: 10.1055/s-0039-3400223
[13]	Chopard R, Albertsen IE, Piazza G. Diagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review[J]. JAMA, 2020, 324(17): 1765-1776. doi: 10.1001/jama.2020.17272
[14]	Thai L, McCarn K, Stott W, et al. Venous thromboembolism in patients with head and neck cancer after surgery[J]. Head Neck, 2013, 35(1): 4-9. doi: 10.1002/hed.22920
[15]	Behranwala KA, Williamson RC. Cancer-associated venous thrombosis in the surgical setting[J]. Ann Surg, 2009, 249(3): 366-375. doi: 10.1097/SLA.0b013e318195c50c
[16]	Haen P, Mege D, Crescence L, et al. Thrombosis Risk Associated with Head and Neck Cancer: A Review[J]. Int J Mol Sci, 2019, 20(11): 2838. doi: 10.3390/ijms20112838
[17]	Fernandes CJ, Morinaga L, Alves JL Jr, et al. Cancer-associated thrombosis: the when, how and why[J]. Eur Respir Rev, 2019, 28(151): 180119. doi: 10.1183/16000617.0119-2018
[18]	Kahn SR, Ducruet T, Lamping DL, et al. Prospective evaluation of health-related quality of life in patients with deep venous thrombosis[J]. Arch Intern Med, 2005, 165(10): 1173-1178. doi: 10.1001/archinte.165.10.1173
[19]	Ah-See KW, Kerr J, Sim DW. Prophylaxis for venous thromboembolism in head and neck surgery: the practice of otolaryngologists[J]. J Laryngol Otol, 1997, 111(9): 845-849. doi: 10.1017/S0022215100138770
[20]	Garritano FG, Andrews GA. Current practices in venous thromboembolism prophylaxis in otolaryngology-head and neck surgery[J]. Head Neck, 2016, 38 Suppl 1: E341-345.
[21]	Rogers SO Jr, Kilaru RK, Hosokawa P, et al. Multivariable predictors of postoperative venous thromboembolic events after general and vascular surgery: results from the patient safety in surgery study[J]. J Am Coll Surg, 2007, 204(6): 1211-1221. doi: 10.1016/j.jamcollsurg.2007.02.072
[22]	Caprini JA, Arcelus JI, Reyna JJ. Effective risk stratification of surgical and nonsurgical patients for venous thromboembolic disease[J]. Semin Hematol, 2001, 38(2 Suppl 5): 12-19.
[23]	Bahl V, Hu HM, Henke PK, et al. A validation study of a retrospective venous thromboembolism risk scoring method[J]. Ann Surg, 2010, 251(2): 344-350. doi: 10.1097/SLA.0b013e3181b7fca6
[24]	Clayburgh DR, Stott W, Cordiero T, et al. Prospective study of venous thromboembolism in patients with head and neck cancer after surgery[J]. JAMA Otolaryngol Head Neck Surg, 2013, 139(11): 1143-1150. doi: 10.1001/jamaoto.2013.4911
[25]	Yarlagadda BB, Brook CD, Stein DJ, et al. Venous thromboembolism in otolaryngology surgical inpatients receiving chemoprophylaxis[J]. Head Neck, 2014, 36(8): 1087-1093. doi: 10.1002/hed.23411
[26]	Cramer JD, Shuman AG, Brenner MJ. Antithrombotic Therapy for Venous Thromboembolism and Prevention of Thrombosis in Otolaryngology-Head and Neck Surgery: State of the Art Review[J]. Otolaryngol Head Neck Surg, 2018, 158(4): 627-636. doi: 10.1177/0194599818756599
[27]	Robson A, Sturman J, Williamson P, et al. Pre-treatment clinical assessment in head and neck cancer: United Kingdom National Multidisciplinary Guidelines[J]. J Laryngol Otol, 2016, 130(S2): S13-S22. doi: 10.1017/S0022215116000372
[28]	Bahl V, Shuman AG, Hu HM, et al. Chemoprophylaxis for venous thromboembolism in otolaryngology[J]. JAMA Otolaryngol Head Neck Surg, 2014, 140(11): 999-1005. doi: 10.1001/jamaoto.2014.2254
[29]	Casazza GC, Bowers CA, MacDonald JD, et al. What Is the Safety and Efficacy of Chemical Venous Thromboembolism Prophylaxis Following Vestibular Schwannoma Surgery?[J]. Otol Neurotol, 2018, 39(2): e131-e136. doi: 10.1097/MAO.0000000000001633
[30]	Venkatesh KP, Ambani SW, Arakelians A, et al. Head and Neck Microsurgeon Practice Patterns and Perceptions Regarding Venous Thromboembolism Prophylaxis[J]. J Reconstr Microsurg, 2020, 36(8): 549-555. doi: 10.1055/s-0040-1710553
[31]	Gavriel H, Thompson E, Kleid S, et al. Safety of thromboprophylaxis after oncologic head and neck surgery. Study of 1018 patients[J]. Head Neck, 2013, 35(10): 1410-1414.
[32]	Lyman GH, Khorana AA, Falanga A, et al. American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer[J]. J Clin Oncol, 2007, 25(34): 5490-5505. doi: 10.1200/JCO.2007.14.1283
[33]	Tipirneni KE, Bauter L, Arnold MA, et al. Association of Prolonged-Duration Chemoprophylaxis With Venous Thromboembolism in High-risk Patients With Head and Neck Cancer[J]. JAMA Otolaryngol Head Neck Surg, 2021, 147(4): 320-328. doi: 10.1001/jamaoto.2020.5151