The relationship between adenoid and tonsil hypertrophy and asthma in children and analysis of changes in asthma after adenotonsillectomy
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Abstract: Adenoid and tonsil hypertrophy in children are closely related to asthma. Their pathogenesis and clinical symptoms are interacted on each other. The unified airway theory believes that the upper and lower respiratory tracts are connected through the release of systemic inflammatory factors. Studies have shown that adenoid and tonsillectomy surgery have a positive effect on the control and development of asthma. The symptoms of postoperative asthma, frequency of attacks, control medication and asthma severity related indicators in children were significantly reduced compared with those before surgery. It has been shown that asthma can increase the incidence of respiratory complications after adenoidectomy and tonsillectomy, so postoperative care after adenotonsillectomy is also important to control asthma. Understanding the relationship between diseases can help clinicians make a more comprehensive diagnosis and treatment.
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Key words:
- child /
- tonsillectomy /
- adenoidectomy /
- asthma
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[1] Kaditis AG, Alonso Alvarez ML, Boudewyns A, et al. Obstructive sleep disordered breathing in 2-to 18-year-old children: diagnosis and management[J]. Eur Respir J, 2016, 47(1): 69-94. doi: 10.1183/13993003.00385-2015
[2] Sedky K, Bennett DS, Carvalho KS. Attention deficit hyperactivity disorder and sleep disordered breathing in pediatric populations: a meta-analysis[J]. Sleep Med Rev, 2014, 18(4): 349-356. doi: 10.1016/j.smrv.2013.12.003
[3] Reddel HK, Bateman ED, Becker A, et al. A summary of the new GINA strategy: a roadmap to asthma control[J]. Eur Respir J, 2015, 46(3): 622-639. doi: 10.1183/13993003.00853-2015
[4] Gunnlaugsson S, Greco KF, Petty CR, et al. Sex differences in the relationship of sleep-disordered breathing and asthma control among children with severe asthma[J]. J Asthma, 2021: 1-9.
[5] Rogers VE, Bollinger ME, Tulapurkar ME, et al. Inflammation and asthma control in children with comorbid obstructive sleep apnea[J]. Pediatr Pulmonol, 2018, 53(9): 1200-1207. doi: 10.1002/ppul.24074
[6] Brockmann PE, Bertrand P, Castro-Rodriguez JA. Influence of asthma on sleep disordered breathing in children: a systematic review[J]. Sleep Med Rev, 2014, 18(5): 393-397. doi: 10.1016/j.smrv.2014.01.005
[7] Bhattacharjee R, Choi BH, Gozal D, et al. Association of adenotonsillectomy with asthma outcomes in children: a longitudinal database analysis[J]. PLoS Med, 2014, 11(11): e1001753. doi: 10.1371/journal.pmed.1001753
[8] Kohli N, DeCarlo D, Goldstein NA, et al. Asthma outcomes after adenotonsillectomy: A systematic review[J]. Int J Pediatr Otorhinolaryngol, 2016, 90: 107-112. doi: 10.1016/j.ijporl.2016.08.030
[9] Goldstein NA, Thomas MS, Yu Y, et al. The impact of adenotonsillectomy on pediatric asthma[J]. Pediatr Pulmonol, 2019, 54(1): 20-26. doi: 10.1002/ppul.24207
[10] Ullmann N, Mirra V, Di Marco A, et al. Asthma: Differential Diagnosis and Comorbidities[J]. Front Pediatr, 2018, 6: 276. doi: 10.3389/fped.2018.00276
[11] Julien JY, Martin JG, Ernst P, et al. Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma[J]. J Allergy Clin Immunol, 2009, 124(2): 371-376. doi: 10.1016/j.jaci.2009.05.016
[12] Goldstein NA, Aronin C, Kantrowitz B, et al. The prevalence of sleep-disordered breathing in children with asthma and its behavioral effects[J]. Pediatr Pulmonol, 2015, 50(11): 1128-1136. doi: 10.1002/ppul.23120
[13] Philpott CM, Erskine S, Hopkins C, et al. Prevalence of asthma, aspirin sensitivity and allergy in chronic rhinosinusitis: data from the UK National Chronic Rhinosinusitis Epidemiology Study[J]. Respir Res, 2018, 19(1): 129. doi: 10.1186/s12931-018-0823-y
[14] Prasad B, Nyenhuis SM, Imayama I, et al. Asthma and Obstructive Sleep Apnea Overlap: What Has the Evidence Taught Us?[J]. Am J Respir Crit Care Med, 2020, 201(11): 1345-1357. doi: 10.1164/rccm.201810-1838TR
[15] Ioachimescu OC, Janocko NJ, Ciavatta MM, et al. Obstructive Lung Disease and Obstructive Sleep Apnea(OLDOSA)cohort study: 10-year assessment[J]. J Clin Sleep Med, 2020, 16(2): 267-277. doi: 10.5664/jcsm.8180
[16] Huang YS, Chin WC, Guilleminault C, et al. Inflammatory Factors: Nonobese Pediatric Obstructive Sleep Apnea and Adenotonsillectomy[J]. J Clin Med, 2020, 9(4): 1028. doi: 10.3390/jcm9041028
[17] Trucco F, Carruthers E, Davies JC, et al. Inflammation in children with neuromuscular disorders and sleep disordered breathing[J]. Sleep Med, 2020, 72: 118-121. doi: 10.1016/j.sleep.2020.03.032
[18] Snidvongs K, Sangubol M, Poachanukoon O. Pediatric Versus Adult Chronic Rhinosinusitis[J]. Curr Allergy Asthma Rep, 2020, 20(8): 29. doi: 10.1007/s11882-020-00924-6
[19] Kaditis AG, Kalampouka E, Hatzinikolaou S, et al. Associations of tonsillar hypertrophy and snoring with history of wheezing in childhood[J]. Pediatr Pulmonol, 2010, 45(3): 275-280.
[20] Levin JC, Gagnon L, He X, et al. Improvement in asthma control and inflammation in children undergoing adenotonsillectomy[J]. Pediatr Res, 2014, 75(3): 403-408. doi: 10.1038/pr.2013.237
[21] Tiotiu A, Novakova P, Guillermo G, et al. Management of adult asthma and chronic rhinitis as one airway disease[J]. Expert Rev Respir Med, 2021: 1-13.
[22] Kicic A, de Jong E, Ling KM, et al. Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium[J]. J Allergy Clin Immunol, 2020, 145(6): 1562-1573. doi: 10.1016/j.jaci.2020.02.018
[23] Marino MJ, Riley CA, Wu EL, et al. The Unified Airway: Does Asthma Influence Paranasal Sinus Pneumatization?[J]. Ear Nose Throat J, 2020, 99(2): 89-93. doi: 10.1177/0145561319848992
[24] KleinJan A, Willart M, van Nimwegen M, et al. United airways: circulating Th2 effector cells in an allergic rhinitis model are responsible for promoting lower airways inflammation[J]. Clin Exp Allergy, 2010, 40(3): 494-504. doi: 10.1111/j.1365-2222.2009.03417.x
[25] Georgopoulos R, Krouse JH, Toskala E. Why otolaryngologists and asthma are a good match: the allergic rhinitis-asthma connection[J]. Otolaryngol Clin North Am, 2014, 47(1): 1-12. doi: 10.1016/j.otc.2013.08.016
[26] Morin A, McKennan CG, Pedersen CT, et al. Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age[J]. J Allergy Clin Immunol, 2020, 146(6): 1358-1366. doi: 10.1016/j.jaci.2020.07.005
[27] Saranz RJ, Lozano A, Lozano NA, et al. Subclinical lower airways correlates of chronic allergic and non-allergic rhinitis[J]. Clin Exp Allergy, 2017, 47(8): 988-997. doi: 10.1111/cea.12938
[28] Huang YS, Guilleminault C, Hwang FM, et al. Inflammatory cytokines in pediatric obstructive sleep apnea[J]. Medicine(Baltimore), 2016, 95(41): e4944.
[29] Zhou J, Wang C, Wu J, et al. Anti-Allergic and Anti-Inflammatory Effects and Molecular Mechanisms of Thioredoxin on Respiratory System Diseases[J]. Antioxid Redox Signal, 2020, 32(11): 785-801. doi: 10.1089/ars.2019.7807
[30] Gabryelska A, Kuna P, Antczak A, et al. IL-33 Mediated Inflammation in Chronic Respiratory Diseases-Understanding the Role of the Member of IL-1 Superfamily[J]. Front Immunol, 2019, 10: 692. doi: 10.3389/fimmu.2019.00692
[31] Samitas K, Carter A, Kariyawasam HH, et al. Upper and lower airway remodelling mechanisms in asthma, allergic rhinitis and chronic rhinosinusitis: The one airway concept revisited[J]. Allergy, 2018, 73(5): 993-1002. doi: 10.1111/all.13373
[32] Calais CJ, Robertson BD, Beakes DE. Association of allergy/immunology and obstructive sleep apnea[J]. Allergy Asthma Proc, 2016, 37(6): 443-449. doi: 10.2500/aap.2016.37.4001
[33] Sánchez T, Castro-Rodríguez JA, Brockmann PE. Sleep-disordered breathing in children with asthma: a systematic review on the impact of treatment[J]. J Asthma Allergy, 2016, 9: 83-91.
[34] Oka S, Goto T, Hirayama A, et al. Association of obstructive sleep apnea with severity of patients hospitalized for acute asthma[J]. Ann Allergy Asthma Immunol, 2020, 124(2): 165-170.e4. doi: 10.1016/j.anai.2019.11.002
[35] Paiva Ferreira L, Paiva Ferreira L, Monteiro TM, et al. Combined allergic rhinitis and asthma syndrome(CARAS)[J]. Int Immunopharmacol, 2019, 74: 105718. doi: 10.1016/j.intimp.2019.105718
[36] Shusterman D, Baroody FM, Craig T, et al. Role of the Allergist-Immunologist and Upper Airway Allergy in Sleep-Disordered Breathing[J]. J Allergy Clin Immunol Pract, 2017, 5(3): 628-639. doi: 10.1016/j.jaip.2016.10.007
[37] Licari A, Brambilla I, De Filippo M, et al. The role of upper airway pathology as a co-morbidity in severe asthma[J]. Expert Rev Respir Med, 2017, 11(11): 855-865. doi: 10.1080/17476348.2017.1381564
[38] Bro ek JL, Bousquet J, Agache I, et al. Allergic Rhinitis and its Impact on Asthma(ARIA)guidelines-2016 revision[J]. J Allergy Clin Immunol, 2017, 140(4): 950-958. doi: 10.1016/j.jaci.2017.03.050
[39] Lohia S, Schlosser RJ, Soler ZM. Impact of intranasal corticosteroids on asthma outcomes in allergic rhinitis: a meta-analysis[J]. Allergy, 2013, 68(5): 569-579. doi: 10.1111/all.12124
[40] Laidlaw TM, Mullol J, Woessner KM, et al. Chronic Rhinosinusitis with Nasal Polyps and Asthma[J]. J Allergy Clin Immunol Pract, 2021, 9(3): 1133-1141. doi: 10.1016/j.jaip.2020.09.063
[41] Kheirandish-Gozal L, Gileles-Hillel A, Alonso-Álvarez ML, et al. Effects of adenotonsillectomy on plasma inflammatory biomarkers in obese children with obstructive sleep apnea: A community-based study[J]. Int J Obes(Lond), 2015, 39(7): 1094-1100. doi: 10.1038/ijo.2015.37
[42] Deschildre A, Pin I, El Abd K, et al. Asthma control assessment in a pediatric population: comparison between GINA/NAEPP guidelines, Childhood Asthma Control Test(C-ACT), and physician's rating[J]. Allergy, 2014, 69(6): 784-790. doi: 10.1111/all.12402
[43] Montalbano L, Cilluffo G, Gentile M, et al. Development of a nomogram to estimate the quality of life in asthmatic children using the Childhood Asthma Control Test[J]. Pediatr Allergy Immunol, 2016, 27(5): 514-520. doi: 10.1111/pai.12571
[44] Sommanus S, Direkwattanachai C, Lawpoolsri S, et al. Accuracy of childhood asthma control test among Thai childhood asthma patients[J]. Asian Pac J Allergy Immunol, 2018, 36(3): 152-158.
[45] Voorend-van Bergen S, Vaessen-Verberne AA, de Jongste JC, et al. Asthma control questionnaires in the management of asthma in children: A review[J]. Pediatr Pulmonol, 2015, 50(2): 202-208. doi: 10.1002/ppul.23098
[46] Amaral R, Carneiro AC, Wandalsen G, et al. Control of Allergic Rhinitis and Asthma Test for Children(CARATKids): Validation in Brazil and cutoff values[J]. Ann Allergy Asthma Immunol, 2017, 118(5): 551-556.e2. doi: 10.1016/j.anai.2017.02.007
[47] Voorend-van Bergen S, Vaessen-Verberne AA, Landstra AM, et al. Monitoring childhood asthma: web-based diaries and the asthma control test[J]. J Allergy Clin Immunol, 2014, 133(6): 1599-605.e2. doi: 10.1016/j.jaci.2013.10.005
[48] Soyer OU, Oztürk F, Keskin O, et al. Perceptions of parents and physicians concerning the Childhood Asthma Control Test[J]. J Asthma, 2012, 49(8): 868-874. doi: 10.3109/02770903.2012.694947
[49] Busino RS, Quraishi HA, Aguila HA, et al. The impact of adenotonsillectomy on asthma in children[J]. Laryngoscope, 2010, 120 Suppl 4: S221.
[50] Kheirandish-Gozal L, Dayyat EA, Eid NS, et al. Obstructive sleep apnea in poorly controlled asthmatic children: effect of adenotonsillectomy[J]. Pediatr Pulmonol, 2011, 46(9): 913-918. doi: 10.1002/ppul.21451
[51] Mutlu LC, Tülübaş F, Alp R, et al. Serum YKL-40 level is correlated with apnea hypopnea index in patients with obstructive sleep apnea sindrome[J]. Eur Rev Med Pharmacol Sci, 2017, 21(18): 4161-4166.
[52] Lavin JM, Shah RK. Postoperative complications in obese children undergoing adenotonsillectomy[J]. Int J Pediatr Otorhinolaryngol, 2015, 79(10): 1732-1735. doi: 10.1016/j.ijporl.2015.07.038
[53] Krajewska Wojciechowska J, Krajewski W, Zatoński T. The Association Between ENT Diseases and Obesity in Pediatric Population: A Systemic Review of Current Knowledge[J]. Ear Nose Throat J, 2019, 98(5): E32-E43. doi: 10.1177/0145561319840819
[54] Lee-Sarwar KA, Bacharier LB, Litonjua AA. Strategies to alter the natural history of childhood asthma[J]. Curr Opin Allergy Clin Immunol, 2017, 17(2): 139-145. doi: 10.1097/ACI.0000000000000340
[55] Hu Y, Cheng J, Jiang F, et al. Season-stratified effects of meteorological factors on childhood asthma in Shanghai, China[J]. Environ Res, 2020, 191: 110115. doi: 10.1016/j.envres.2020.110115
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