阻塞性睡眠呼吸暂停与动脉粥样硬化关系的研究进展

孙海丽; 秦彦文; 魏永祥

doi:10.13201/j.issn.2096-7993.2020.10.023

阻塞性睡眠呼吸暂停与动脉粥样硬化关系的研究进展

- 1.
  首都医科大学附属北京安贞医院耳鼻咽喉科(北京，100029)
- 2.
  北京市心肺血管研究所上气道功能障碍相关心血管病重点实验室
基金项目:
国家自然科学基金(No：81870355)

详细信息

通讯作者: 魏永祥，E-mail：weiyongxiang@vip.sina.com

中图分类号: R766

收稿日期: 2019-08-20

刊出日期: 2020-10-05

Progress in obstructive sleep apnea and atherosclerosis

More Information

Corresponding author: WEI Yongxiang, E-mail: weiyongxiang@vip.sina.com

Received Date: 20 August 2019

Publish Date: 05 October 2020

摘要

- 睡眠呼吸暂停，阻塞性 /
- 动脉粥样硬化 /
- 间歇低氧 /
- 内皮功能
Abstract: Obstructive sleep apnea(OSA) is a common sleep-disordered disease which is characterized by repetitive narrowing or occlusion of the pharynx causing intermittent hypoxia, repetitive arousals, sleep deprivation, and excessive daytime sleepiness. OSA can contribute to atherosclerosis through direct and indirect mechanisms. Animal and clinical studies have shown a close relationship between OSA and atherosclerosis and its risk factors. However, current studies showed inconsistent results. In the future, further research both basic and clinical studies need to be fulfilled. Future studies are needed to investigate underlying mechanisms between OSA and atherosclerosis.
- sleep apnea, obstructive /
- atherosclerosis /
- intermittent hypoxia /
- endothelial function

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