The research of prognosis and evaluation of vocal leukoplakia by narrow band image endoscope
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摘要: 目的 对比白光内镜，观察窄带成像对声带白斑病变性质的预判能力。方法 声带白斑患者46例，同时进行白光及窄带成像模式图像采集并予分型，通过与术后病理结果对比，产生不同检查方法应用受试者工作特征曲线及曲线下面积(AUC)，借以判断不同检查方法的诊断准确性。结果 白光模式AUC为0.642，其预测声带早期癌敏感度为41.67%，特异度为97.06%;NBI模式AUC为0.896，敏感度为58.33%，特异度为97.06%(P < 0.05)。结论 窄带成像模式较白光模式对声带白斑良恶性的识别能力强，对声带白斑恶性病变预测的敏感度更高。Abstract: Objective To explore the ability of narrowband imaging to predict the nature of leukoplakia of the vocal cords.Method In 46 patients with leukoplakia of the vocal cords, laryngoscopy was performed simultaneously with white light and narrow-band imaging modes. Type the images and compare with the postoperative pathological results. The receiver operating characteristic curve and the area under the curve are used to judge the diagnostic accuracy of different examination methods.Result The AUC in white light mode is 0.642, which predicts the sensitivity of early vocal cord cancer is 41.67%, and the specificity is 97.06%; For NBI mode, the AUC is 0.896(P < 0.05) and its sensitivity and specificity is 58.33% and 97.06%, respectively.Conclusion Compared with white light mode, NBI mode is more sensitive and accurate in identification of benign and malignant vocal cord lesions.
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Key words:
- vocal cord leukoplakia /
- narrow band image /
- prognosis
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表 1 白光及NBI模式下声带白斑病变的病理结果比较
例(%) 病理诊断 例数 鳞状上皮增生 轻度异型增生 中度异型增生 重度异型增生 原位癌/ 浸润癌 良性构成比/% 恶性构成比/% 白光 1型 34 23(67.65) 4(11.76) 0(0) 3(8.82) 4(11.76) 79.41 20.59 2型 6 5(83.33) 0(0) 1(16.67) 0(0) 0(0) 100.00 0 3型 6 1(16.67) 0(0) 0(0) 0(0) 5(83.33) 16.67 83.33 NBI Ⅰ型 22 19(86.36) 3(13.64) 0(0) 0(0) 0(0) 100.00 0 Ⅱ型 7 4(57.14) 1(14.29) 0(0) 1(14.29) 1(14.29) 71.43 28.57 Ⅲ型 9 4(44.44) 0(0) 2(22.22) 1(11.11) 2(22.22) 66.67 33.33 Ⅳ型 6 1(16.67) 0(0) 0(0) 3(50.00) 2(33.33) 16.67 83.33 Ⅴ型 2 0(0) 0(0) 0(0) 1(50.00) 1(50.00) 0 100.00 
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