-
Abstract: Summary Sarcomatoid carcinoma, a malignant tumor containing both epithelial-derived malignant cells and malignant mesenchymal cells. Microscopically, cancer cells and sarcoma cells migrate to each other, and CK and Vimentin are simultaneously expressed. A rare case of tonsillar sarcomatoid carcinoma is discussed in our department with dysphagia as the first symptom.
-
Key words:
- tonsillar neoplasms /
- sarcomatoid carcinoma
-
表 1 免疫组织化学分析
免疫组织化学类型 扁桃体肿瘤 肺肿瘤 CK 强阳性 弱阳性 Vimentin 强阳性 弱阳性 CD68(PGM1) 阴性 弱阳性 CD34 阴性 阴性 CK20 阴性 未做 CK5-6 阴性 阴性 CK7 阴性 未做 Desmin 阴性 阴性 HMB45 阴性 阴性 LCA 阴性 未做 Melan-A 阴性 阴性 p63 阴性 阴性 S100 阴性 阴性 SMA 阴性 阴性 CD1a 阴性 阴性 CD21 阴性 阴性 CD23 阴性 未做 Ki67 未做 60%+ p40 未做 阴性 TTF1 未做 阴性 -
[1] Ghanem TA. Transoral robotic-assisted microvascular reconstruction of the oropharynx[J]. Laryngoscope, 2015, 121: 580-582.
[2] Ryosuke H, Chihaya I, Takayuki T, et al. Reactive tonsillar enlargement with strong 18F-FDG uptake after chemotherapy for tonsillar diffuse large B-cell lymphoma[J]. J Pediatr Hematol Oncol, 2011, 33: 87-88.
[3] 杨柳, 刘世喜, 陈敏, 等. 扁桃体肿瘤临床病理分析[J]. 华西医学, 2016, 31(9): 1546-1550. https://www.cnki.com.cn/Article/CJFDTOTAL-HXYX201609018.htm
[4] 方铣华, 林雪平. 肉瘤样癌及癌肉瘤的新认识[J]. 肿瘤研究与临床, 2005, 17(2): 138-139. doi: 10.3760/cma.j.issn.1006-9801.2005.02.036
[5] Oktay M, Kokenek-Unal T D, Ocal B, et al. Spindle cell carcinoma of the tongue: a rare tumor in an unusual location[J]. Patholog Res Int, 2011, 2011: 572381. https://pubmed.ncbi.nlm.nih.gov/21403898/
[6] Mermod M, Hiou-Feige A, Bovay E, et al. Mouse model of postsurgical primary tumor recurrence and regional lymph node metastasis progression in HPV-related head and neck cancer[J]. Int J Cancer, 2018, 142: 2518-2528. doi: 10.1002/ijc.31240
[7] 张文静, 屠春林. 肺肉瘤样癌1例并文献复习[J]. 临床肺科杂志, 2017, 22(4): 761-762. doi: 10.3969/j.issn.1009-6663.2017.04.051
[8] Burgess B, Ananthanarayanan V, Charous S. Hyalinizing Clear Cell Carcinoma of the Tonsil: A Case Report[J]. Head Neck Pathol, 2017, 11: 1-4. doi: 10.1007/s12105-017-0785-2
[9] Pagano A, Dennis K. Cribriform adenocarcinoma of the minor salivary gland arising in the tonsil with metastasis to a cervical lymph node: A case report with description of fine needle aspiration cytology[J]. Diagn Cytopathol, 2017, 45: 468-471. doi: 10.1002/dc.23687
[10] 何海蕾, 刘忠龙, 马春跃, 等. 口腔颌面-头颈部癌肉瘤10例临床分析[J]. 上海口腔医学, 2017, 26(5): 569-572. https://www.cnki.com.cn/Article/CJFDTOTAL-SHKY201705029.htm
[11] 成伟, 陈健智. 原发性扁桃体恶性肿瘤误诊、诊断及鉴别诊断探讨[J]. 山东大学耳鼻喉眼学报, 2012, 26(3): 61-62, 67. https://www.cnki.com.cn/Article/CJFDTOTAL-SDYU201203020.htm
[12] Pardo J, Aisa G, De Alava E, et al. Primary mixed squamous carcinoma and osteosarcoma(carcinosarcomas)of the lung have a CGH mapping similar to primitive squamous carcinomas and osteosarcomas[J]. Diagn Mol Pathol, 2008, 17: 151-158. doi: 10.1097/PDM.0b013e31815d05b3
[13] 张悦, 郭雪君, 韩锋锋, 等. 肺肉瘤样癌2例并文献复习[J]. 临床肺科杂志, 2011, 16(6): 900-902. doi: 10.3969/j.issn.1009-6663.2011.06.040
[14] 姜元芹, 黄煦格, 张炳煌, 等. 5例下咽肉瘤样癌的临床分析[J]. 中国卫生标准管理, 2017, 8(26): 28-31. doi: 10.3969/j.issn.1674-9316.2017.26.015
[15] 于维冯, 薛森耀, 司志真, 等. 膀胱肉瘤样癌10例临床分析[J]. 临床医学研究与实践, 2018, 3(11): 40-42. https://www.cnki.com.cn/Article/CJFDTOTAL-YLYS201811019.htm