Cervial vestibular-evoked myogenic potential induced by galvanic vestibular stimulation in normal people
-
摘要: 目的 通过对正常人群中乳突直流电刺激颈肌前庭诱发肌源性电位测试, 建立正常人的数值范围, 寻求新的前庭功能的检测方法。方法 选取20例正常耳进行乳突直流电刺激颈肌前庭诱发肌源性电位检测。SPSS 18.0分析p13潜伏期、n23潜伏期、振幅、p13-n23波间期和各参数的耳间不对称率及左右耳间各参数的比较。结果 20耳乳突直流电刺激颈肌前庭诱发肌源性电位均稳定引出, 重复性好。p13潜伏期为(11.52±3.05) ms, n23潜伏期为(15.31±3.38) ms, 振幅为(40.55±27.93)μV, p13-n23波间期为(3.53±1.38) ms。p13潜伏期、n23潜伏期、振幅、p13-n23波间期的耳间不对称率分别为(6.96±6.79)%、(6.47±5.93)%、(28.08±26.42)%、(16.61±11.11)%。所有受检者左右耳比较p13潜伏期、n23潜伏期、振幅、p13-n23波间期等参数差异无统计学意义。结论 建立实验室乳突直流电刺激颈肌前庭诱发肌源性电位在正常人中的数值范围, 可为听神经病、前庭神经病的临床诊疗和机制研究提供新的思路和方法。
-
关键词:
- 乳突直流电刺激 /
- 颈肌前庭诱发肌源性电位
Abstract: Objective To establish a new method for detecting vestibular function by testing cervical vestibular-evoked myogenic potential induced by galvanic vestibular stimulation in normal population.Method Twenty normal ears were tested for cervical vestibular evoked myogenic potential induced by galvanic vestibular stimulation. SPSS 18.0 software was used to analyze the obtained data.Result In all healthy subjects mastoid-forehead galvanic vestibular stimulation produced a positive-negative biphasic EMG responses on SCM ipsilateral to the cathodal electrode. The latency of p13 was(11.52±3.05) ms. The latency of n23 was(15.31±3.38) ms. The amplitude of p13-n23 was(40.55±27.93) μV. The interval of p13-n23 was(3.53±1.38) ms. The interaural asymmetry ratio(AR, %) of p13, n23 latency, the amplitude and interval were respectively(6.96±6.79)%, (6.47±5.93)%, (28.08±26.42)% and (16.61±11.11)%. There was no significant difference in all parameters between the right and left ears of all subjects.Conclusion The value of cervical vestibular-evoked myogenic potential induced by galvanic vestibular stimulation in normal subjects can be established to explore methods for diagnosis, treatment and researching mechanism of auditory neuropathy and vestibular neuropathy. -
-
表 1 20耳GVS-cVEMP各参数的具体数值
p13潜伏期/ms n23潜伏期/ms 振幅/ μV p13-n23波间期/ms 均数 11.52 15.31 40.55 3.53 标准误 3.05 3.38 27.93 1.38 最小值 7.00 10.95 2.38 0.90 最大值 17.75 21.05 107.90 6.75 
下载: 导出CSV
表 2 10例受检者的GVS-cVEMP各参数的耳间不对称率
% p13潜伏期 n23潜伏期 振幅 p13-n23波间期 均数 6.96 6.47 28.08 16.61 标准误 6.79 5.93 26.42 11.11
下载: 导出CSV
-
[1] 毕潇, 周慧芳, 苏娟, 等. 不同年龄段前庭诱发肌源性电位参数的正常值[J]. 临床耳鼻咽喉头颈外科杂志, 2016, 30(13): 1016-1020. https://www.cnki.com.cn/Article/CJFDTOTAL-LCEH201613003.htm
[2] Welgampola MS, Colebatch JG. Characteristics and clinical applications of vestibular-evoked myogenic potentials[J]. Neurology, 2005, 64(10): 1682-1688. doi: 10.1212/01.WNL.0000161876.20552.AA
[3] Ying C, Yusuke K, Kimitaka K. A study on vestibular-evoked myogenic potentials via galvanic vestibular stimulation in normal people[J]. J Otol, 2018, 13(1): 16-19. doi: 10.1016/j.joto.2017.09.001
[4] Caporali JF, Utsch Gonçalves D, Labanca L, et al. Vestibular Evoked Myogenic Potential(VEMP)Triggered by Galvanic Vestibular Stimulation(GVS): A Promising Tool to Assess Spinal Cord Function in Schistosomal Myeloradiculopathy[J]. PLoS One, 2016, 10(4): e4672.
[5] Curthoys IS. A critical review of the neurophysiological evidence underlying clinical vestibular testing using sound, vibration and galvanic stimuli[J]. Clin Neurophysiol, 2010, 121(2): 132-144. doi: 10.1016/j.clinph.2009.09.027
[6] Murofushi T, Takegoshi H, Ohki M, et al. Galvanic-evoked myogenic responses in patients with an absence of click-evoked vestibulo-collic reflexes[J]. Clin Neurophysiol, 2002, 113(2): 305-309. doi: 10.1016/S1388-2457(01)00738-6
[7] Murofushi T, Monobe H, Ochiai A, et al. The site of lesion in "vestibular neuritis": study by galvanic VEMP[J]. Neurology, 2003, 61(3): 417-418. doi: 10.1212/01.WNL.0000076480.11463.17
[8] Welgampola MS, Ramsay E, Gleeson MJ, et al. Asymmetry of balance responses to monaural galvanic vestibular stimulation in subjects with vestibular schwannoma[J]. Clin Neurophysiol, 2013, 124(9): 1835-1839. doi: 10.1016/j.clinph.2013.03.015
[9] Labanca L, De Morais CJ, Da SCS, et al. Vestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human T-cell lymphotropic virus type 1-associated myelopathy[J]. PLoS One, 2018, 13(7): e200536.
-
图(1)
表(2)
计量
- 文章访问数: 656
- PDF下载数: 99
- 施引文献: 0