腮腺肿瘤术后发生Frey综合征的影响因素分析

韩宇; 温立婷; 田克勇; 陈俊; 陈阳; 石力; 邓志宏; 查定军; 邱建华

doi:10.13201/j.issn.1001-1781.2019.09.014

腮腺肿瘤术后发生Frey综合征的影响因素分析

- 空军军医大学西京医院耳鼻咽喉头颈外科(西安, 710032)
基金项目:
国家自然科学基金面上项目(No:81870719)

陕西省自然科学基金项目(No:2018SF-240)

详细信息

通讯作者: 查定军,E-mail:zhadjun@fmmu.edu.cn

中图分类号: R782.05

收稿日期: 2019-02-27

Analysis of predictors for Frey syndrome after parotidectomy

- Department of Otolaryngology Head and Neck Surgery, Xijing Hospital, Air Force Medical University, Xi'an, 710032, China

More Information

Corresponding author: CHA Dingjun, E-mail: zhadjun@fmmu.edu.cn

Received Date: 27 February 2019

摘要

摘要: 目的:分析腮腺肿瘤术后发生Frey综合征的影响因素,明确软组织修补片SIS用于预防腮腺肿瘤切除术后Frey综合征的疗效。方法:对95例腮腺肿瘤患者资料进行回顾性分析,明确患者年龄、性别、肿瘤位置与大小、病理类型、手术方式、术中SIS使用与术后Frey综合征发生的相关性。结果:95例腮腺肿瘤切除术后患者Frey综合征的发生率为25.3%。术后Frey综合征的发生与患者年龄、性别、肿瘤位置与大小、病理类型、手术方式等均无显著相关性(P>0.05);术中SIS的使用可减少术后Frey综合征的发生(P<0.01)。结论:Frey综合征是腮腺肿瘤切除术后常见并发症,术中软组织修补片SIS的应用可有效降低腮腺肿瘤术后Frey综合征的发生率。
- 腮腺肿瘤 /
- Frey综合征 /
- 影响因素 /
- 软组织修补片
Abstract: Objective: To analysis the data of the patients with parotid tumors, clarify the contributing factors of Frey syndrome, and to evaluate the role of soft tissues membrane SIS in prevention of Frey syndrome after parotidectomy. Method: The data of 95 patients who suffered from parotid tumors and underwent parotidectomy were included in this study. The relationship between the patients' age, sex, tumor location,tumor size, disease pathology, type of resection, SIS application and the incidence of Frey syndrome were statistically analyzed. Result: The incidence of Frey syndrome after parotidectomy for 95 patients was 25.3%. Age, sex, tumor location and size, disease pathology, type of resection did not appear to be associated with development of Frey syndrome(P>0.05). SIS application was the only statistically significant factor(P<0.01), and SIS could prevent Frey syndrome after parotidectomy. Conclusion: Frey syndrome is one of the common complicationsafter parotidectomy. Implantation of SIS is an effective method for prevention of Frey syndrome after parotidectomy.
- parotid neoplasms /
- Frey syndrome /
- predictors /
- soft tissues membrane

HTML全文

参考文献(21)

[1]	MOTZ K M,KIM Y J.Auriculotemporal Syndrome(Frey Syndrome)[J].Otolaryngol Clin North Am,2016,49:501-509.
[2]	DRUMMOND P D.Mechanism of gustatory flushing in Frey's syndrome[J].Clin Auton Res,2002,12:144-146.
[3]	CIUMAN R R,OELS W,JAUSSI R,et al.Outcome,general,and symptom-specific quality of life after various types of parotid resection[J].Laryngoscope,2012,122:1254-1261.
[4]	GUNTINAS-LICHIUS O,GABRIEL B,KLUSSMANN J P.Risk of facial palsy and severe Frey's syndrome after conservative parotidectomy for benign disease:analysis of 610 operations[J].Acta Otolaryngol,2006,126:1104-1109.
[5]	TUNCEL A,KARAMAN M,SHEIDAEI S,et al.A comparison of incidence of Frey's syndrome diagnosed based on clinical signs and Minor's test after parotis surgery[J].Kulak Burun Bogaz Ihtis Derg,2012,22:200-206.
[6]	LEE C C,CHAN R C,CHAN J Y.Predictors for Frey Syndrome Development After Parotidectomy[J].Ann Plast Surg,2017,79:39-41.
[7]	LIN H J,HSIAO J R,CHANG J S,et al.Resected specimen size:A reliable predictor of severe Frey syndrome after parotidectomy[J].Head Neck,2019,[Epub ahead of print]
[8]	ALBERGOTTI W G,NGUYEN S A,ZENK J,et al.Extracapsular dissection for benign parotid tumors:a meta-analysis[J].Laryngoscope,2012,122:1954-1960.
[9]	ZHENG C Y,CAO R,GAO M H,et al.Comparison of surgical techniques for benign parotid tumours:a multicentre retrospective study[J].Int J Oral Maxillofac Surg,2019,48:187-192.
[10]	李烁,张小萌,高春生,等.保留浅叶的腮腺深叶良性肿瘤切除术临床分析[J].临床耳鼻咽喉头颈外科杂志,2015,29(15):1360-1362.
[11]	MANOLA M,MOSCILLO L,SIMEON V,et al.The Effectiveness of Sternocleidomastoid Flap Versus Superficial Musculoaponeurotic System Flap for the Prevention of Frey Syndrome and Facial Depressed Deformity in Parotid Surgery for Pleomorphic Adenoma[J].Ann Plast Surg,2018,80:125-129.
[12]	张萌,曹蜀炜,刘建敏.运用胸锁乳突肌瓣防止腮腺术后味觉出汗综合征和面部畸形的研究[J].临床耳鼻咽喉头颈外科杂志,2016,30(6):482-484.
[13]	HOJJAT H,SVIDER P F,RAZA S N,et al.Economic Analysis of Using Free Fat Graft or Acellular Dermis to Prevent Post-parotidectomy Frey Syndrome[J].Facial Plast Surg,2018,34:423-428.
[14]	GHASSEMI A,MODABBER A,BRZOSKA P O,et al.Vascularised fatty tissue:its role in prevention of the symptoms of Frey syndrome after parotidectomy[J].Br J Oral Maxillofac Surg,2018,56:877-880.
[15]	IRVINE L E,LARIAN B,AZIZZADEH B.Locoregional parotid reconstruction[J].Otolaryngol Clin North Am,2016,49:435-446.
[16]	LI C,YANG X,PAN J,et al.Graft for prevention of Frey syndrome after parotidectomy:a systematic review and meta-analysis of randomized controlled trials[J].J Oral Maxillofac Surg,2013,71:419-427.
[17]	AIZAWA T,KUWABARA M,KUBO S,et al.Polyglycolic Acid Felt for Prevention of Frey Syndrome After Parotidectomy[J].Ann Plast Surg,2018,81:438-440.
[18]	毛涌,常永军,张晓林,等.功能性腮腺外科在腮腺良性肿瘤切除中的运用[J].临床耳鼻咽喉头颈外科杂志,2018,32(23):1810-1812.
[19]	WANG C,WU D,MAO C,et al.The preventive effect of decellularized pericardial patch against Frey's syndrome following the superficial parotidectomy[J].J Craniomaxillofac Surg,2019,47:832-836.
[20]	AMBRO B T,ZIMMERMAN J,ROSENTHAL M,et al.Nasal septal perforation repair with porcine small intestinal submucosa[J].Arch Facial Plast Surg,2003,5:528-529.
[21]	D'EREDITÀ R.Porcine small intestinal submucosa(SIS)myringoplasty in children:A randomized controlled study[J].Int J Pediatr Otorhinolaryngol,2015,79:1085-1089.