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摘要: 目的:探讨外鼻皮肤肿瘤的病理类型、分布情况以及发病特点等,以提高对该类疾病的诊治水平,为外鼻皮肤肿瘤的临床诊治提供参考。方法:对遂宁市中心医院和四川省人民医院2008-01-2017-12期间收治的187例外鼻皮肤肿瘤患者的性别、发病年龄、病变部位、病变大小、病理类型、病程、相关危险因素等进行回顾性分析。结果:外鼻皮肤良性肿瘤患者的男女比例为1.10:1.00,外鼻皮肤恶性肿瘤患者的男女比例为0.97:1.00;不同性别患者良恶性肿瘤构成之间差异无统计学意义(χ2=0.169,P=0.681)。外鼻皮肤肿瘤的发病高峰年龄为60岁以上老年人群,占71.1%。不同年龄段患者良恶性肿瘤构成比之间差异有统计学意义(χ2=31.378,P<0.001),恶性肿瘤的构成比例随着年龄的增加而升高,差异有统计学意义(χ2趋势=28.741,P<0.001)。良性外鼻皮肤肿瘤以鼻翼(28例,22.2%)、鼻根(25例,19.8%)、鼻背(23例,18.3%)、鼻尖(22例,17.5%)和鼻旁(18例,14.3%)最为常见,恶性外鼻皮肤肿瘤以鼻翼(18例,28.5%)、鼻背(15例,24.6%)、鼻尖(11例,18.0%)为主。恶性肿瘤中,以表皮细胞来源的基底细胞癌最多(44例,72.1%),鳞状细胞癌次之(11例,18.0%)。结论:外鼻皮肤恶性肿瘤具有老年人群是其发病高峰年龄的发病特点,以皮肤基底细胞癌最为多见,针对发病构成最多的基底细胞癌,应做到早发现、早诊断、早治疗。Abstract: Objective: To explore the pathological types, distribution and characteristics of external nose skin tumors, in order to improve the diagnosis and treatment of such diseases, and provide reference for the clinical diagnosis and treatment of external nose skin tumors. Method: The gender, age of onset, lesion location, lesion size, pathological type, course of disease and related risk factors of all 187 cases with external nose skin tumors in our hospital from January 2008 to December 2017 were analyzed retrospectively. Result: The sex ratio of patients with external nasal skin benign tumors was 1.10:1.00, and that of patients with external nasal skin malignant tumors was 0.97:1.00. There was no significant difference in the composition of benign and malignant patients(χ2=0.169, P=0.681). The peak age of skin tumors of the external nose is over 60 years old, accounting for 71.1%(133/187). There was a significant difference in the ratio of benign to malignant tumors among different age groups(χ2= 31.378, P<0.001). The ratio of malignant tumors increased with age(χ2trend=28.741, P<0.001). The most common benign external nasal skin tumors were alar nasi(28 cases, 22.2%), nasal root(25 cases, 19.8%), dorsal nasal(23 cases, 18.3%), tip nasi(22 cases, 17.5%) and paranasal(18 cases, 14.3%). Malignant external nasal skin tumors were alar nasi(18 cases, 28.5%), dorsal nasal(15 cases, 24.6%) and tip nasi(11 cases, 18.0%). Epidermal cell-derived basal cell carcinoma was the most common malignant tumor(44 cases, 72.1%), followed by squamous cell carcinoma(11 cases, 18.0%).Conclusion: External nasal skin malignancies have the characteristics of the elderly at the peak age of onset, skin basal cell carcinoma is the most common, for the incidence of basal cell carcinoma constitutes the largest, so that early detection, early diagnosis, early treatment.
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Key words:
- external nose /
- skin tumor /
- clinical analysis
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